The Senior Scientist position will be part of the Scale-up Lab based in Devens, MA and reports to the Director of Pilot Plant Network and External Manufacturing (PPNE). The candidate will be responsible for scale-up and execution of upstream and downstream processes for all assets within the Biologics Development portfolio. The candidate will work closely with the process, analytical and manufacturing teams to improve internal process tech transfer procedures and collaborate on new technology initiatives. In addition, the individual will provide support (on as-needed basis) to external GMP-related activities (investigations, deviations, CAPA, change control) within BD's external portfolio. Prior experience with Pilot, Manufacturing or Biologics Process development is a plus.
Key Responsibilities- Lead/support daily operations in the Scale-up Lab, including bioreactor fill/harvest, inoculation, sampling, feeding, operating chromatographic and filtration skids, buffer preparation, run monitoring/troubleshooting
- Prepare/review technical documents including campaign summary reports and batch records
- Participate in cross-functional teams to support process investigations, process development, scale-up, and tech transfer to clinical and commercial manufacturing
- Introduce, evaluate, and implement innovative new process technologies and capabilities
- Identify and implement process transfer improvement initiatives with internal stakeholders
- Support GMP-related activities for BD External Manufacturing programs (as needed)
- Maintain a safe work environment in the Scale-up lab
- Works with an operational excellence mindset
Qualifications- Ph.D. with 2-4 years experience, M.S. with 4-6 years experience or B.S. with 7-9 years experience in Chemical/Biochemical Engineering, Biochemistry, or related field with relevant industrial and/or academic experience.•
- Strong knowledge of either Upstream Processing (Mammalian Cell Culture) or Downstream Processing (Harvest, Chromatography and Filtration)•
- Working knowledge of cGMP •
- Excellent oral and written communication skills •
- Works well in a team and as an individual •
- Prior experience in single-use manufacturing and automation.
- Working knowledge of cGMP is a plus•
- Knowledge of statistics, design of experiment, and data analysis is desired.
We hire for skills and capabilities, not just credentials - if this role excites you, but doesn't perfectly match your resume, we encourage you to apply anyway.
Compensation Overview:Devens - MA - US: $123,120 - $149,196
The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully - carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.
Benefits:Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans - including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).
U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.
Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.
Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.
U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits
How We WorkWhere you work matters - because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.
