Element Biosciences

Staff Scientist, Surface Chemistry

Element Biosciences$158K — $197K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • PhD in relevant scientific field such as chemistry or bioengineering
  • 5+ years of industry experience in surface chemistry or biomolecular interfaces
  • Demonstrated track record of publications and patents in the field
  • In-depth understanding of cell biology and extracellular matrix interactions
  • Prior experience with functional coatings for biological assays
  • Familiarity with next-generation sequencing and multiomics applications
  • Strong independent planning and problem-solving skills

Responsibilities

  • Design and develop innovative surface chemistry techniques for sequencing applications
  • Conduct experiments to analyze cell-material interactions
  • Lead product development from experimental design to data analysis
  • Troubleshoot and resolve issues related to surface performance
  • Collaborate on transferring research solutions to manufacturing
  • Maintain active participation in laboratory experimentation and troubleshooting
  • Contribute to patent applications and technical reports

Benefits

  • Stock options
  • Discretionary annual bonus
  • No-cost health insurance plans
  • 401k with company match
  • Flexible paid time off
Full Job Description
We are seeking a highly motivated Staff Scientist to join our surface chemistry team and provide scientific leadership in the development of innovative new products in the field of next-generation sequencing and multiomics applications. In this role, you will lead execution across multiple projects, drive innovation through original ideas and thought leadership, and serve as a key scientific collaborator across functions to translate research concepts into robust, manufacturable products. This role will report to the Director, Surface Chemistry and will be a San Diego based role.

If you possess the following and want to make a meaningful impact, we invite you to explore this role.

Essential Functions and Responsibilities:
  • Design, develop, and evaluate novel surface chemistry approaches to enable next-generation sequencing/multiomics applications
  • Design and evaluate novel surface chemistry solutions on microfluidic and lab-on-chip devices, with a strong understanding of how device geometry and flow conditions influence surface performance and assay outcomes
  • Define and lead product development efforts, including experimental design, prototyping, functional testing, and data analysis
  • Troubleshoot performance issues related to surface fouling, non-specific binding, or cell compatibility
  • Identify and resolve experimental challenges related to assay design, protocol execution, reagent selection, and surface performance
  • Support the transfer of surface chemistry solutions from research into product development and manufacturing, in collaboration with process development and operations teams
  • Maintain hands-on scientific leadership, setting the direction for laboratory experimentation and troubleshooting while mentoring junior scientists and guiding their technical development
  • Contribute innovative ideas and technical insight to early-stage concept development and feasibility assessments
  • Contribute technical expertise to invention disclosures and patent applications in collaboration with the IP legal team and senior technical leadership
  • Collaborate effectively with colleagues in product management, assay development, engineering, and manufacturing to ensure alignment and successful execution
  • Prepare and deliver high-quality technical reports and presentations that summarize findings, support decision-making, and document development progress

Education and Experience:
  • PhD in chemistry, materials science, biochemistry, bioengineering, physics, or a related field
  • 6+ years of relevant industry experience in surface chemistry, materials science, or biomolecular interfaces in life sciences or diagnostics
  • Strong publication and presentation record, with contributions to patents or novel methods
  • Deep expertise in surface chemistry, polymer chemistry and biomolecule-surface interactions is required
  • Background in NGS, genomics, proteomics or multiomics platforms is required
  • Familiarity with microfluidic device design principles and an understanding of how channel geometry, surface-to-volume ratios, and flow dynamics influence surface chemistry performance and assay outcomes; experience with device fabrication (e.g., soft lithography, PDMS) or working with commercial lab-on-chip platforms is preferred
  • Familiarity with surface analytical techniques such as AFM, ellipsometry, FTIR, SEM, TOF-SIMS, and XPS are preferred
  • Familiarity with manufacturing constraints, process transfer or scale-up
  • Operate with a high degree of independence in experimental planning, execution, and data interpretation, requiring minimal day-to-day supervision
  • Apply strong scientific judgment to extrapolate from existing expertise and address novel or ambiguous technical challenges
  • Proactively identify risks, knowledge gaps, and opportunities, and propose data-driven paths forward that shape project scope and organizational priorities
  • Communicate with clarity and purpose across disciplines, enabling alignment, informed decisions, and efficient collaboration

Physical Requirements:
  • Ability to lift up to 20 pounds
  • The position requires physical activity and the handling of chemicals. Candidates are required to follow the safety protocols and be familiar with personal protective equipment (PPE) while working in the laboratory environment

Location:
  • San Diego (on-site)

Travel:
  • Up to 5%

Job Type:
  • Full-time, Exempt

Base Compensation Pay Range:
  • $158,000 - $197,000


In addition to base compensation noted above, you will be eligible for stock options, discretionary annual bonus, no cost health insurance plans, 401k with company match, and flexible paid time off.

Please note: Base compensation will depend on multiple factors, including geographic location, qualifications, and experience.

About Element Biosciences

Element Biosciences is a biotechnology company that develops innovative genetic analysis tools. The company was founded in 2017 by a team of experienced scientists and engineers. Element Biosciences' technology platform enables researchers to analyze genetic information with higher accuracy and speed than traditional methods. The company's products are used in various applications, including drug discovery, disease diagnosis, and agricultural research. Element Biosciences is headquartered in Mountain View, California.
Learn more about Element Biosciences
Size
100 employees
Industry
Founded
2017

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