We are seeking a professional-level organic chemist to join our drug discovery team. You'll contribute to hit-to-lead development, lead optimization, and synthetic route development. The ideal candidate will have hands-on synthetic chemistry experience, strong lab skills, and excel in collaborative problem-solving.
RESPONSIBILITIES:- Utilize cutting-edge synthetic methodologies and techniques to design and execute efficient syntheses of target compounds for existing chemical series and novel series;
- Independently conduct multi-step synthesis and optimization through effective reaction planning, troubleshooting, and systematic analysis;
- Purify and characterize compounds using a variety of techniques including column chromatography, crystallization, trituration, LCMS, NMR, HPLC;
- Work under the supervision of the Director of Chemistry or the Project Manager in order to achieve the objectives of the project in line with those of the client;
- Research current literature to formulate synthetic and medicinal chemistry strategies. Evaluate and implement new reactions, techniques and technologies to advance the projects;
- Maintain lab notebook, instrument and inventory records in accord with department guidance;
- Maintain all appropriate standards for lab safety and hazardous material management.
REQUIREMENTS:- MSc (10 years of experience) or PhD (5 years of experience) in Organic or Medicinal Chemistry;
- Project management experience;
- Strong knowledge of and experience in current synthetic methods;
- Expertise in isolation and purification techniques such as silica gel chromatography and HPLC as well as modern analytical techniques such as NMR and LCMS;
- Knowledge of good laboratory and safety practices.
- Excellent written, organizational and documentation skills;
- Proactive with strong interpersonal skills; able to thrive in a team-based environment;
- Demonstrated ability to troubleshoot and creatively problem solve;
- Proficiency in Microsoft Office (Word, Excel and PowerPoint);
- Ability to communicate progress effectively with colleagues and managers;
