PhD in immunology or a related field with 5+ years of postdoctoral and/or industry experience
Proven track record in cellular immunology within a translational setting
Technical expertise in immune assays and primary cell cultures
Experience in immune-oncology and large data analytics is a plus
Strong verbal and written communication skills
Responsibilities
Design and conduct in vitro studies emphasizing immunological testing of human and animal samples using advanced techniques
Perform immune-monitoring experiments with mouse and clinical samples
Provide scientific input to optimize project progression
Maintain detailed experimental records and prepare analytical presentations
Deliver clear presentations at project meetings for organizational alignment
Support the creation of internal and regulatory documents
Collaborate with Immunobiology, Biotherapeutics, and Translational Science teams to share scientific knowledge
Benefits
High-impact opportunity to advance novel biologic therapies targeting solid tumors
Mentorship and guidance for professional growth in translational immunology and drug development
Exposure to integrated drug discovery processes
A mission-driven environment where contributions lead to real-world impact
Full Job Description
We\'re hiring a Principal Scientist to join our collaborative Translational Sciences team focused on designing and advancing first-in-class immune-engaging biologics. This is a hands-on, lab-based role where your contributions directly shape the next generation of immunotherapy.
What You\'ll Work on
In this role you will execute translational immunology research to support IND enabling activities and phase I clinical studies in oncology. Experience in immune-assay development and expertise in human immunology and T cell immunobiology are required. The role involves experimental design (CRO and internal) and execution (bench work) as well as interpretation and presentation of results. This is an exciting opportunity for a highly collaborative and creative scientist who is eager to position novel immunotherapies in the cancer immunology treatment landscape. Close collaboration and matrix working with members of the Immunobiology, Biotherapeutics and Translational Sciences teams are expected. Evidence for a track record of scientific and/or project achievements is preferred.
Design and conduct in vitro studies with an emphasis on immunological testing of human and animal samples using state-of-the-art techniques including immune cell functional assays, multi-parameter FACS including BD and Cytek instruments, cell separation, multiplex assays, cell toxicity, proliferation
Perform immune-monitoring related experiments of mouse and clinical samples (tumor, whole blood, PBMC, sera, etc.)
Provide scientific input to optimize project progression
Maintain records of experiments in electronic notebooks, analyze data and prepare presentations
Deliver clear, concise presentations at portfolio and project meetings to enable organizational alignment
Support the authoring of essential internal and regulatory documents
Partner with Immunobiology, Biotherapeutics and Translational Science teams to ensure proactive sharing of scientific know-how across the organization
Ensure compliance with all health and safety protocols
What You Bring
PhD in immunology or a related fields with 5+ years of postdoctoral and/or industry experience
Patient focused - dedication to enabling translation of preclinical research into impactful human therapies
Proven track record in cellular immunology in translational setting demonstrating technical expertise in immune assays and primary cell cultures
Experience in the field of immune-oncology and large data analytics is a plus
Capable of clarifying problems and working in collaboration with team members to identify solutions
Strong verbal and written communication skills
What You\'ll Gain
A high-impact opportunity to help advance novel biologic therapies targeting solid tumors
Mentorship and guidance to support your professional growth in translational immunology and drug development
Exposure to integrated drug discovery across immunobiology, protein engineering, in vivo models, and translational research
A mission-driven environment where your contributions matter and discovery meets real-world impact
Additional Info
This is a full-time, onsite position based in Branford, CT
We offer competitive salary, benefits, equity, and paid time off
Learn more about our science and our team at www.evolveimmune.com
