Full Job Description
Associate Director/Director, Data Management
We are seeking a highly motivated Associate Director/Director, Data Management. Reporting to the Vice President, Head of Biometrics, this is a newly created role that will build Climb Bio's Phase 1 through 3 data management capability from the ground up, serving as the operational owner who ensures databases, vendors, and timelines deliver clean, submission-ready data at every milestone.
Key Responsibilities:
• Design and build the clinical database architecture for clinical studies, establishing edit checks, structures, and specifications that meet the program's analysis and regulatory requirements
• Own user acceptance testing (UAT) for clinical database builds end-to-end, from test plan development through final sign-off prior to DB going live
• Manage data management timelines and deliverables across clinical studies, holding vendors accountable to milestones from first patient in through database lock
• Direct the selection and ongoing performance oversight of data management CROs and vendors, serving as the primary escalation point for data quality and timeline issues
• Partner with Biostatistics, Clinical Operations, and Regulatory to align data management plans, CRF design, and database specifications with study protocols
• Establish data management standards, SOPs, and quality control processes that scale as Climb Bio's clinical portfolio grows
• Lead data cleaning, query resolution, and reconciliation activities to ensure inspection-ready, submission-quality data at database lock
• Represent Data Management in cross-functional program governance, reporting on database timelines, risks, and trade-offs
Qualifications:
• Bachelor's degree in life sciences or a related field
• 10+ years of clinical data management experience (12+ years for Director-level candidates), including experience taking a database through Phase 3 database lock
• Demonstrated experience designing clinical databases and leading user acceptance testing (UAT) execution
• Experience managing CRO and data management vendor relationships, including performance oversight
• Working knowledge of GCP and applicable regulatory requirements for clinical data management
Preferred Qualifications:
• Experience in a small, fast-paced biotech environment
• Proficiency with industry-standard clinical database and EDC platforms
This is a hybrid position, based out of our Wellesley, MA office.
Base salary offered may vary depending on the individual's skills, experience, and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, Life & Disability, 401k company match, generous paid time off, and equity.
