Bachelor's or Master's Degree in a relevant scientific discipline
Experience with cell passaging and bioreactor operations (50L, 250L, 500L)
Authorization to work in the U.S. without restrictions
Preferred: Certified Biomanufacturing Professional (CBP)
Preferred: Lean Six Sigma certification
Preferred: GMP or Bioprocess Manufacturing Training Certification
Familiarity with GMP and GLP standards
Responsibilities
Design and optimize upstream bioprocesses for biologics and vaccines
Plan and execute studies to enhance cell growth and product quality
Analyze data to identify critical process parameters
Collaborate with cross-functional teams to support manufacturing
Author and review technical documentation and SOPs
Troubleshoot process deviations and implement improvements
Foster a collaborative team environment
Benefits
Comprehensive medical coverage
Dental and vision options
Life and disability insurance
401(k) with company match
Paid vacation and holidays
Full Job Description
Job Description
The Upstream Process Development Scientist is responsible for the development, optimization, characterization, and scale-up of upstream bioprocesses supporting the production of biologics, vaccines, cell therapies, or other biotechnology products. This role applies scientific expertise in cell culture, media development, process monitoring, and bioreactor operations, utilizing 50L, 250L, and 500L single-use bioreactor systems to improve process performance, product quality, and manufacturing efficiency. The scientist collaborates closely with cross-functional teams, including Process Development, Manufacturing, Analytical Sciences, and Quality, to support technology transfer, process validation, and commercial manufacturing activities. This role may also contribute to continuous improvement initiatives, troubleshooting efforts, and the implementation of innovative bioprocess technologies to enable successful large-scale biopharmaceutical manufacturing.
Design, develop, optimize, and scale upstream bioprocesses, including mammalian cell culture, and bioreactor operations, to support research, clinical, and commercial manufacturing objectives.
Plan and execute process development studies to improve cell growth, productivity, product quality, and overall process robustness using sound scientific and engineering principles.
Analyze experimental data, and identify critical process parameters to support process understanding, scale-up, and technology transfer activities.
Collaborate with cross-functional teams, including Manufacturing, Analytical Sciences, Quality, and Process Engineering, to advance development programs and support manufacturing operations.
Author and review study protocols, technical reports, process descriptions, regulatory documentation, and standard operating procedures (SOPs) in compliance with applicable quality standards.
Troubleshoot process deviations and technical challenges, implement corrective actions, and support continuous improvement initiatives to enhance process performance and operational efficiency.
Foster a collaborative, engaged, and team-oriented work environment.
May also perform smaller studies from the 10L down to Shake Flask range.
Qualifications
Bachelor's or Master's Degree in Chemical Engineering, Biochemical Engineering, Biotechnology, Biology, Biochemistry, Microbiology, Pharmaceutical Sciences, or related scientific discipline.
Familiar with cell passaging including vial thaw, inoculation and harvest processes for 50L, 250L, and 500L single-use bioreactors.
Authorization to work in the United States indefinitely without restrictions or sponsorship
Preferred Experience:
Certified Biomanufacturing Professional (CBP)
Lean Six Sigma Green Belt or Black Belt
GMP or Bioprocess Manufacturing Training Certification
Proficient with recording data via eLNs, following SOPs and validation reports.
Familiar with GMP and GLP standards.
Additional Information
This position is Full-Time, Monday - Friday, 8:00 a.m. - 5:00 p.m. Candidates currently living within a commutable distance of Spring House, PA are encouraged to apply.
Excellent full-time benefits including comprehensive medical coverage, dental, and vision options
Life and disability insurance
401(k) with company match
Paid vacation and holidays
About Eurofins Lancaster Laboratories
Eurofins Lancaster Laboratories is a leading contract research organization (CRO) providing analytical, research and testing services to clients in the pharmaceutical, biopharmaceutical, biotechnology, crop protection, chemical, food, environmental and consumer products industries. The company was founded in 1961 and has grown to become one of the largest CROs in the world, with over 50 locations in 20 countries. Eurofins Lancaster Laboratories is part of the Eurofins Scientific Group, a global leader in bioanalytical testing and laboratory services. The company's services include method development and validation, stability testing, quality control testing, and regulatory compliance support.
