Flagship Pioneering

(Senior) Scientist, Computational Neuroscience

Flagship Pioneering$132K — $259K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • MSc or PhD in relevant field (Computational Neuroscience, Physics, Applied Mathematics, Computer Science, AI/ML)
  • 2+ years of industry or postdoctoral experience (5+ years for MSc)
  • Strong experience with computational modeling of neural systems
  • Hands-on experience with machine learning/statistical methods for time-series data
  • Proficiency in Python and scientific computing libraries (NumPy, SciPy, Pandas)
  • Familiarity with ML frameworks (PyTorch, TensorFlow)
  • Comfortable in ambiguous R&D settings and building methods from first principles

Responsibilities

  • Develop end-to-end computational pipelines for biophysical neuron modeling
  • Implement machine learning and statistical methods to analyze neural recordings
  • Shape technical roadmap by proposing and evaluating modeling approaches
  • Collaborate closely with team on modeling and inference strategies
  • Analyze large-scale neural datasets to derive insights

Benefits

  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Broad range of other benefits
Full Job Description
The Role:

FL119 is seeking a (Senior) Scientist, Computational Neuroscience to join our team. Leveling is flexible based on experience. This role will focus on building scalable computational pipelines for biophysical modeling and applying machine learning techniques to large-scale neural datasets.

The role is based in Cambridge, Massachusetts, with a preference for on-site engagement. International candidates are welcome to apply.

How You Will Contribute:
  • Own the development of end-to-end computational pipelines for biophysical modeling of neurons and neural populations.
  • Implement machine learning and statistical inference methods to construct and analyze bio-realistic networks from neural recordings.
  • Actively shape the technical roadmap by proposing, prototyping, and evaluating modeling and inference approaches in close collaboration with the broader team.

The Ideal Candidate Will Have:
  • MSc or PhD in Computational Neuroscience, Physics, Applied Mathematics, Computer Science, AI/ML, or a related field.
  • 2+ years of full-time industry or postdoctoral experience (5+ years for MSc).
  • Strong experience with computational modeling of neural systems.
  • Hands-on experience applying machine learning or statistical methods to complex time-series data.
  • Proficiency in Python and scientific computing libraries (e.g., NumPy, SciPy, Pandas), and familiarity with ML frameworks such as PyTorch or TensorFlow.
  • Comfort working in high-ambiguity R&D environments and building novel methods from first principles.
  • Passion for working at the intersection of AI and experimental biology.

The salary range for this role is $132,000 - $259,000. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. FL119 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL119's good faith estimate as of the date of publication and may be modified in the future.

About Flagship Pioneering

Flagship Pioneering is a life sciences innovation enterprise that conceives, creates, resources, and develops first-in-category life sciences companies. The firm operates through its Flagship Labs unit, which is a dedicated innovation foundry that invents and launches transformative companies. Flagship Pioneering has created over 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. The firm's portfolio includes companies in the fields of therapeutics, health technologies, and sustainability. Flagship Pioneering was founded in 2000 and is headquartered in Cambridge, Massachusetts.
Learn more about Flagship Pioneering
Size
500 employees
Industry

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