Exciting opportunity at MSK:
The Olayan Center for Cancer Vaccines, a key pillar in MSK's immuno-oncology transformation, is seeking a
Senior Researcher, Molecular Biology to join our RNA Therapeutics Lab and support manufacture, characterization and innovation of mRNA-based personalized cancer vaccines. This role will focus on innovating up from conventional DNA/RNA production, as well as driving design and process development improvements to the platform
You will have a unique opportunity to help build the lab from the ground up, shape workflows and pioneer new approaches. You won't just be joining a lab - you'll be helping to design it, define it, and set the stage for years of discovery!
Role Overview:- Production of mRNA vaccines using in vitro transcription for mRNA vaccines.
- Development of in-house DNA assembly platforms for rapid DNA template production and analytical release.
- Drive investigation and innovation of novel mRNA-based and DNA technologies, such as ribozymes, ligation, and mRNA display for clinical and research applications.
- Collaborate with formulation, analytical, research and GMP arms to pursue optimal mRNA designs and processes.
- Analyzing data and creating graphs using appropriate software (e.g., SoftMax Pro, Excel, Prism) and data visualization tools; writing reports of results and methods used and presenting data at regular lab meetings.
- Perform routine maintenance, operation and inventory for a variety of laboratory instruments and reagents, which may include, but are not limited to: microplate readers, IVT reagents, electrophoretic instrumentation, Tapestation, centrifuges.
- Following proper safety recommendations and handling procedures for different biological and chemical materials and ensuring others in the laboratory adhere to proper safety procedures.
- Training other laboratory personnel as needed.
- Performing all other duties as assigned.
Key Qualifications:- B.S. in molecular biology/biochemistry or related field with 7 years of relevant experience, or M.S. with 4 years of experience.
- Ph.D is preferred.
- Strong molecular biology skills well beyond conventional cloning techniques
Core Skills:- Exceptional attention to detail and strong analytical skills.
- Ability to thrive in a fast-paced research environment, managing multiple projects while maintaining precision.
- Critical thinking and problem-solving skills to troubleshoot experimental challenges.
- Outstanding interpersonal and communication skills and the ability to interact across all levels in a confident, concise, professional manner.
- Enthusiasm and dedication to MSK's vision, mission and values.
Additional Information:
- Location: NYC
- Schedule: Onsite
- Reporting to the Associate Director
Helpful Links:
- Compensation Philosophy
- Benefits
Pay Range: $77,100.00 - $119,400.00
FSLA Status: Exempt
