Who we are looking for:
ASCO is seeking a Senior Guideline Specialist to help lead the development and modernization of our evidence-based clinical guidance products.

In this role, the Senior Guideline Specialist will work alongside multidisciplinary teams of global oncology experts, leading rigorous systematic literature reviews and supporting the full lifecycle of clinical practice guidelines, living guidelines, as well as other guidance products.

Discover a career where your expertise in evidence-based medicine, systematic reviews, and emerging technology can help advance clinical guidance and make a meaningful impact on oncology care.

Remote candidates welcome or at primary location in Alexandria, VA.

Responsibilities

• Lead the end-to-end design and execution of clinical practice guidelines and other guidance products. Oversee rigorous evidence-based systematic literature review development-including protocol development, literature search and screening, data extraction, quality appraisal, and report writing-in strict alignment with the ASCO Guidelines Methodology Manual.
• Provide advanced methodological expertise to guide and support Guidelines Advisory Groups, expert panels, and internal working teams throughout the guideline development cycle.
• Champion and integrate advanced guideline development platforms and AI-augmented tools to optimize workflows, including literature search and screening, citation management, data extraction, quality appraisal, and evidence synthesis.
• Spearhead the creation of guideline-derived clinical tools, pathways, informatics, and resources to support dissemination, implementation, and evaluation initiatives.
• Drive continuous quality improvement and standardization initiatives to streamline systematic reviews and accelerate guideline development timelines.
• Deliver expert briefings and reports on guideline content, methodology, and informatics to the Board of Directors, Evidence Based Medicine Committee, and other key governance stakeholders

Required Education and Experience

• Master's degree in related field (e.g., Epidemiology, Public Health, Health Research Methodology, Healthcare Research, or a related scientific discipline).
• 5+ years of progressive experience in clinical practice guideline development, systematic literature reviews, or evidence-based medicine synthesis.
• Demonstrated track record of managing technical clinical documents through complex multi-stakeholder review cycles and successfully publishing in peer-reviewed medical journals.
• Proven experience utilizing and implementing digital guideline authoring platforms, systematic review software, and AI-assisted research tools.
• Command of MS Word, Excel, Adobe Acrobat, and similar office software systems
• Strong expertise in content management systems (CMS) and managing large, complex digital libraries of technical and scientific documents.

Preferred Education and Experience

• Ph.D. in Health Research Methodology, Epidemiology, Public Health
• Previous experience with medical specialty societies or volunteer groups is desirable

Competencies

• Advanced capability to leverage modern guideline authoring platforms and AI-augmented productivity tools to accelerate data extraction and evidence synthesis, without sacrificing methodological integrity, clinical accuracy, or compliance standards.
• Proven emotional intelligence, professional maturity, and diplomatic tact required to consult, engage, and build consensus among world-class oncology experts and multi-disciplinary panels.
• Exceptional communication skills, including written and presentation skills, with a demonstrated ability to synthesize complex scientific data into clear, actionable insights for diverse stakeholder audiences.
• Elite organizational, prioritization, and time-management skills, with a track record of managing competing priorities, meeting stringent deadlines, and maintaining meticulous attention to detail across complex, multi-phase projects.
• Superior problem-solving and analytical capabilities to evaluate conflicting clinical data, navigate methodological ambiguity, and drive sound, evidence-based conclusions.

ADA/Physical Requirements

Extended periods seated or standing at a desk.

High use of computer and other office technology equipment.

Travel

1-10 days/yr

Compensation

This is an exempt position. The hiring salary range for this position is $107,600-$130,000 annualized.

The range displayed reflects the minimum and maximum annualized salary ASCO expects to provide for a new hire for the position across the U.S. We thoughtfully determine and design offers based on the selected candidate's relevant experience and qualifications.

Generous Benefits Package:

• Hybrid Work Environment
• Open Leave Policy
• Paid Family Leave
• 13 Paid Holidays per Calendar Year
• Staff Appreciation Days
• 401(k): 7.5% Employer Contribution
• Medical/Dental/Vision
• Employee Assistance Program
• Fertility and Family Forming
• Healthcare Concierge
• Flexible Spending Account(s)
• Healthcare Savings Account
• Disability and Life Insurance

Applications are accepted and reviewed on a rolling basis. The job posting will remain active throughout the candidate application evaluation process.