Job Title: Senior Director, Clinical Development
Location: San Diego or Remote U.S.
Job Type: Full-Time
Position SummaryReporting to the Vice President, Clinical Development, the Senior Director, Clinical Development will be responsible for providing critical input into the strategy, development, management, and implementation of clinical studies by closely working across the clinical organization; leading multi-disciplinary teams charged with guiding clinical development and subsequent regulatory submissions.
Essential Job Functions and Responsibilities- Lead the development, review and approval of clinical and regulatory documents, including protocols, investigator brochures, clinical study reports participate in the writing and review of, study reports and other clinical and
- Provide medical and scientific oversight for assigned oncology programs, operational staff, CROs, and clinical trial sites in all areas related to the therapeutic programs
- Serve as a clinical subject matter expert for internal teams, investigators, and external stakeholders supporting the assigned solid tumor program
- Establish and approve scientific methods for design and implementation of applicable clinical protocols, data collection systems and final reports
- Provide medical and safety oversight for clinical studies, including SAE review, safety signal evaluation, and participation in safety governance activities
- Lead the analysis, interpretation, and communication of clinical data to support development, regulatory, and portfolio decision-making
- Build and maintain relationships with principal investigators and key opinion leaders to support the successful execution of clinical development programs
- Contribute clinical expertise to regulatory strategy and health authority engagements, supporting major regulatory submissions and development milestones across the product lifecycle
- Provide scientific leadership, guidance, and mentorship to cross-functional clinical teams on medical, scientific, and therapeutic area topics
- Lead the preparation and review of clinical study reports and other regulatory documents to support global submissions
- Partner cross-functional and collaboratively across clinical operations, safety, biometrics, regulatory, medical writing, medical affairs to advance programs and support key business objectives
- Serve as a therapeutic area subject matter expert, presenting clinical and scientific data to internal and external stakeholders
- Support publication strategy and the development and review of publications
Preferred Qualifications- MD required, advanced medical or life sciences or a related area degree preferred with 10+ years of experience in the life sciences industry or an equivalent combination of academic and industry experience
- Oncology solid tumor clinical development experience is required
- 8+ years of experience in clinical development
- Proven track record of leading clinical development programs from early-phase trials through regulatory submissions
- Strategic leadership skills with the ability to inspire, mentor and manage cross-functional teams
- Demonstrated ability to excel in a fast-paced, entrepreneurial environment and effectively adjust priorities in response to changing business needs
- Excellent communication and interpersonal skills, with the ability to collaborate effectively with internal and external stakeholders
- Strong analytical and problem-solving abilities, with a strategic mindset
- This position requires periodic/regular travel, including up to 15 percentage of work time, which may include overnight travel
Physical Demands and Work EnvironmentPhysical Demands:
- Constant or continuous use of a computer keyboard, monitor, and mouse to perform a variety of tasks
- Constant or frequent sitting, standing, or walking
- May lift and/or move objects of various weights
Work Environment:
- Remote: Home office; expected to travel to and work from the Company's headquarters in San Diego from time to time
- San Diego-based: On-site requirement (Monday through Thursday)
- Noise level in the work environment is usually moderate
- Fast-paced, time sensitive environment with frequently changing priorities
- Handle multiple projects simultaneously
Reasonable accommodations may be provided to enable qualified individuals with disabilities to perform the essential functions of the position.
Salary RangeThe salary range for this position is $332,000 to $360,000 per year. The final pay offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and years of experience within the job and the industry, education, and skills and certifications.
BenefitsProvided they meet all eligibility requirements under the applicable plan documents, employees (and their eligible dependents) will be eligible to enroll in group healthcare plans that offer medical, dental, vision, and basic life and AD&D insurance. Additional benefit programs include short-term and long-term disability insurance, flexible spending accounts, health savings accounts, and voluntary insurance programs, including voluntary life, AD&D accident, and critical illness. Employees will also be able to enroll in the Company's 401(k) plan. In addition, employees will accrue 10 hours of paid vacation time every month and accrue 1 hour of paid sick leave for every 30 hours worked. Employees also enjoy 17 paid holidays each calendar year, including a winter closure, subject to applicable Company policies. All benefits are subject to the terms and conditions of the applicable plan documents and Company policies, which may be amended from time to time.
Other CompensationThe hired candidate will be eligible to receive an annual discretionary bonus and an equity award, subject to the terms of the applicable employment agreement, plan documents, and Company policies.
The information above is intended to provide a general description of benefits and other compensation and is not a substitute for applicable plan documents or company policies.
Applications for this position are anticipated to close on November 30, 2026. For more information about this posting, please contact careers@avenzotx.com.
