THE OPPORTUNITYVir Biotechnology is seeking a detail-oriented, highly motivated Bioanalytical Scientist to join our Translational Development team.
In this role, you will develop and implement bioanalytical methods to support large-molecule programs at both preclinical and clinical stages. Responsibilities include designing and executing immunochemistry assays (e.g., ELISA, MSD, anti-drug antibody assays) and preparing samples for LC-MS/MS analysis. You will contribute to immunoassay development across multiple programs and analyze preclinical samples for drug concentrations and anti-drug antibodies.
This description outlines the primary responsibilities and requirements but is not exhaustive; additional related duties may be assigned as needed.
This position is based at our San Francisco headquarters, with an expectation of at least 4 days per week on site.
WHAT YOU'LL DO- Develop and optimize bioanalytical methods to support large-molecule preclinical and clinical candidates, providing bioanalytical input across research and development stages.
- Plan and coordinate method development and sample analysis activities in alignment with program and development timelines.
- Troubleshoot and evaluate complex bioanalytical methods to identify and implement robust solutions.
- Prepare and characterize assay reagents using standard biochemical techniques (e.g., protein conjugation, concentration determination, UV/Vis spectrophotometry).
- Maintain thorough and timely documentation in electronic lab notebooks; compile, analyze, and interpret data.
- Present experimental plans and results in group and cross-functional settings to communicate assay development progress.
- Perform routine instrument maintenance, calibrations, and performance checks as needed.
- Collaborate closely with other assay development team members to achieve project and departmental goals.
WHO YOU ARE AND WHAT YOU BRING- PhD with 1+ years, MS with 6+ years, or BS with 8+ years of relevant industry experience.
- Experience that combines hands-on laboratory work with project oversight; prior experience managing CROs for clinical and nonclinical assay development/validation is a plus.
- Demonstrated understanding of GLP/GCP principles as they pertain to sample handling and storage, bioanalytical assay development, sample analysis, and laboratory operations.
- Strong technical expertise with platforms used to characterize large-molecule therapeutics, including assays with complex handling and preparation (e.g., enzymatic, ligand-binding, cell-based assays, and LC-MS/MS assays) across a range of biological matrices (e.g., serum, plasma).
- Familiarity with PK/PD concepts and their application to assay design, selection, and range determination.
- Prior work in GCP/GLP/GMP environments is advantageous but not required.
- Prior work utilizing LC/MS/MS is advantageous but not required
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WHO WE ARE AND WHAT WE OFFERThe expected Salary range for this position is $116,000 to $146,000 per year. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.
Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person's experience and qualifications.
