This position is part of a broader Large Molecule CMC Analytical and Formulation team. This is an opportunity to collaborate on formulation, process and analytical development activities across a broad range of large molecules, that cross the blood-brain barrier, for treating challenging diseases. Key Accountabilities/Core Job Responsibilities: - Assist in the development of chromatography, electrophoresis, spectroscopy and mass spectrometry-based analytical methods to be used for product release, stability, and characterization testing. - Contribute to the design and execution of experiments for demonstrating method robustness and performance. - Prioritize and perform timely testing that enables bioprocess and formulation development teams to meet project timelines. - Critically evaluate analytical data to support method development decisions and product quality comparisons. - Maintain accurate and timely experiment records in electronic laboratory notebook (ELN). - Summarize and present data in a clear and meaningful way. - Author and review analytical test methods and development reports. Qualifications/Skills: - B.S. or M.S. in Analytical Chemistry, Biochemistry, Chemical Engineering, Pharmaceutical Sciences or related scientific discipline with 2+ years of CMC analytical development experience in biotech/pharma. - Hands-on experience with various analytical methods for measuring the purity of biologics and residual process impurities (i.e. chromatography, capillary electrophoresis, spectroscopy, LC-MS, etc.). - Experience with chromatography and mass spectrometry acquisition and data analysis software. - Excellent laboratory, critical thinking, scientific problem-solving, and organizational skills. - Familiarity with good documentation requirements and industry guidance. - Knowledge of statistical approaches for data interpretation and analytical method development. - Motivated, detail-oriented, naturally curious individual with a creative approach to scientific problem solving. - Excellent spoken and written communication skills. Salary Range: $106,000.00 to $138,000.00 . Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.