S2P Process Design & Standards Senior Manager

Vertex Pharmaceuticals Incorporated

$139K — $208K *
Business Services
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • 7+ years in Procurement, S2P, or Supply Chain process design roles.
  • Expertise in process standardization and controls.
  • Proven ability to influence in cross-functional teams.
  • Strong verbal and written communication skills for stakeholder engagement.
  • Experience in developing technical and process documentation.

Responsibilities

  • Lead design and maintenance of S2P, SRM, and Category Strategy frameworks.
  • Drive consistency and scalability across various categories and regions.
  • Define guidance on decision-making and control points across processes.
  • Conduct benchmarking assessments to identify improvement needs.
  • Lead continuous improvement initiatives using Lean methodologies.
  • Align process standards with digital and analytics requirements.
  • Partner with various teams to ensure adherence to enterprise process standards.

Benefits

  • Inclusive market-leading medical, dental, and vision benefits.
  • Generous paid time off, including a summer and winter company shutdown.
  • Educational assistance programs, including student loan repayment.
  • 401(k) plan with matching contributions.
  • Commuting subsidy and charitable donation matching.
Full Job Description

Job Description

General Summary:

The Lead, Process Design & Standards is responsible for leading and advancing enterprise Source to Pay (S2P) process design and standards. This role serves as a senior process architect and steward for S2P, helping ensure clarity, consistency, scalability, and alignment with enterprise governance and strategy.
Operating within the S2P Center of Excellence, this role focuses on how S2P should work across the organization and partners closely with Category and Sourcing teams, User Orchestration, and Execution Systems & Analytics COE teams to help ensure that process intent is translated into user experiences, systems, and insights—without owning execution, configuration, or operational reporting.

Key Duties and Responsibilities:

  • Set the Foundation: Process Architecture & Standards
    •    Lead the design, documentation, and maintenance of end to end S2P, SRM and Category Strategy process frameworks, standards, policies, controls, and decision models.
    •    Serve as a senior steward of S2P, SRM and Category Strtategy process integrity, helping drive consistency and scalability across categories, regions, and business units.
    •    Define clear process decision guidance, handoffs, and control points across sourcing, contracting, buying channels, invoicing, and payment.
    •    Advance process standards that align with enterprise governance, audit, and compliance expectations in partnership with Finance, Legal, Risk, and Compliance.
  • Process Excellence & Optimization
    •    Apply a market and benchmarking lens to assess S2P, SRM and Category Strategy process maturity and identify improvement opportunities.
    •    Lead the design, documentation, and maintenance of end to end S2P, SRM, and Category Strategy process frameworks, standards, policies, controls, and decision models.
    •    Serve as a senior steward of S2P, SRM, and Category Strategy process integrity, helping drive consistency and scalability across categories, regions, and business units.
    •    Define and maintain process performance measures covering efficiency, effectiveness, compliance, and user experience.
    •    Lead continuous improvement efforts, leveraging Lean and process excellence methodologies.
    •    Use performance insights to inform prioritization of process enhancements and future state design decisions.
  • Digital & Analytics Alignment
    •    Advance process standards that are digitally enabled by design and aligned with current and future S2P, SRM and Category Strategy technology roadmaps.
    •    Partner with the Execution Systems & Analytics COE to translate process standards into system design principles, configuration guardrails, and analytics requirements, without owning system configuration or reporting execution.
    •    Provide clarity on process intent to support effective solution design, adoption sequencing, and insight generation.
  • Cross COE & Enterprise Partnership
    •    Partner with the User Orchestration COE to ensure process standards are reflected in intake design, buying channel guidance, and decision flows.
    •    Partner with Category and Sourcing teams to embed enterprise process standards into category strategies and sourcing ways of working.
    •    Support S2P governance forums with insight into process health, maturity, risks, and improvement priorities.

Knowledge and Skills:

  • 7+ years of experience in Procurement, S2P, or Supply Chain process design, optimization, or governance roles.
  • Deep expertise in process standardization, controls, and performance management within complex organizations.
  • Strong ability to influence outcomes in matrixed, cross functional environments.
  • Strong verbal and written communication skills, with the ability to influence and build alignment across cross functional stakeholders.
  • Experience developing and maintaining technical and process documentation, including standards, procedures, and decision frameworks.

Education and Experience:

  • Bachelor's degree

#LI-Hybrid

#LI-AA1


At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$139,100 - $208,700

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.  

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

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