Research Scientist I, Biochemistry and Microbiology Division

Qualifications

• Ph.D. in a scientific discipline with 1-2 years of academic or industry experience.
• Working knowledge of protein structure-function relationships and mechanistic enzymology.
• Experience with directed evolution or protein engineering.
• Experience developing or miniaturizing plate-based assays; familiarity with liquid-handling automation is required.
• Strong ability to multitask and perform effectively under pressure while maintaining high attention to detail.
• Excellent organizational and communication skills, including rigorous lab notebook practices.
• Proven 'good hands' at the bench and the ability to perform careful and consistent experiments.

Responsibilities

• Design enzyme engineering strategies based on knowledge of enzyme chemistry and structure.
• Translate assays for various enzyme families into high-throughput formats for testing.
• Establish high-throughput kinetic workflows and manage data generation and analysis.
• Advise on clone design and protein purification strategies with the Cloning and Protein Purification Core.
• Validate successful hits from screening and biochemically characterize promising candidates.
• Collaborate with the Bioinformatics Core to interpret results and inform future engineering cycles.

Benefits

• Annual discretionary profit-sharing bonus
• Participation in Employee Stock Ownership Plan (ESOP) after two years of service
• Exceptional benefits package at a nominal cost, including a 10% 401k match