Job Description

Research Associates, Representatives

Job Description: The candidate will be responsible for process chemistry and development activities that delivers milligram to gram quantities of active pharmaceutical ingredients (API) for oligonucleotide therapeutics. This includes assisting in developing synthetic routes, methods, and techniques in preparing, separating, purifying, analyzing, quantifying, and resolving oligonucleotide process components and objectives.

Essential duties and responsibilities include but are not limited to:

• Studying and implementing oligonucleotide project objectives and targets related to engineering and chemical requirements to better understand requirements. Additionally, they will be encouraged to study emerging trends in oligonucleotide analytical methods and synthesis development, review professional and technical publications, establish personal networks, and benchmark state-of-the-art practices.
• Execute process development experiments and activities. Documents analyses by completing experiment notebooks and records; implementing process chemistry applications and analyzing results of new oligonucleotide synthesis and purification methods and processes. This includes preparing process descriptions and writing technical reports to support internal technology transfer into manufacturing and preparation of client CMC submissions.
• Applies laboratory experience in chemistry and separations to issues of process optimization, scale-up and laboratory process transfer to mid and kilo scale GMP manufacturing while adhering to standard operating procedures (SOP's) and current good manufacturing practices to maintain compliance integrity (cGMP).
• Executes Design of Experiments (DOE) and Proven Acceptable Range (PAR) experiments to support design space understanding and process validation as they relate to oligonucleotide synthesis, process chromatography, and other purification and isolation techniques.

Qualifications

Internal and External Qualifications:

The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

• Bachelors, Masters, or University Degree in chemistry, chemical engineering, or science. Equivalent or a combination of education and (a minimum of 2 years) experience in a pharmaceutical environment.
• Ability to work both independently and in a team setting on a variety of projects and use individual discretion to meet required time-sensitive objectives for assigned projects.
• Excellent math, documentation, communication and operational troubleshooting skills. General proficiency with tools, systems, and procedures required to accomplish the job.
• Proven knowledge of oligonucleotide synthesis, purification, ultrafiltration, conjugation, and lyophilization is advantageous.
• Knowledge of and skill in using computer software and hardware applications, including Microsoft products and the Internet.

Additional Details

This job has a full time weekly schedule. Applications for this job will be accepted until at least September 25, 2026 or until the job is no longer posted.

The full-time equivalent pay range for this position is $76,080.00 - $118,875.00/yr plus eligibility for bonus, stock and benefits. Our pay ranges are determined by role, level, and location. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. During the hiring process, a recruiter can share more about the specific pay range for a preferred location. Pay and benefit information by country are available at: https://careers.agilent.com/locations

Travel Required:
No

Shift:
Day

Duration:
No End Date

Job Function:
R&D