Cedars-Sinai

Project Scientist - Inner Ear Research & Cochlear Gene Therapy - Otolaryngology

Cedars-Sinai$88K — $105K *
Healthcare
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD, MD, MD/PhD, VMD, AuD or equivalent doctoral degree required.
  • Postdoctoral experience in inner ear research highly preferred.
  • Experience performing auditory function tests such as ABR and DPOAE in mice preferred.
  • Hands-on experience with cochlear injection techniques preferred.
  • Familiarity with IACUC-approved protocols for mouse models preferred.
  • Experience with acquired hearing loss mouse models is a definite plus.

Responsibilities

  • Assist in preparing grant proposals and research publications.
  • Participate in research publications and presentations as author or co-author.
  • Develop and implement new research techniques and protocols.
  • Conduct hands-on laboratory experiments.
  • Analyze and interpret research data, providing summaries and compilations.
  • Lead and train Staff Research Associates and Research Fellows as needed.
  • Manage daily laboratory operations under supervision.

Benefits

  • Mentorship from an experienced investigator with industry and academic background.
  • Opportunities to pursue independent funding, including NIH grants.
  • Exposure to a variety of disciplines in gene therapy and synthetic biology.
  • Collaborative environment working on cutting-edge gene delivery technology.
Full Job Description
Job Description

Principal Investigator Dr. Volkan Ergin is seeking a Project Scientist to join the Ergin Lab in the Department of Otolaryngology at Cedars-Sinai Medical Center.

Effective gene therapies require both efficient delivery vehicles and well-designed therapeutic cargos. The Ergin Lab addresses these challenges by engineering next-generation AAV vectors for targeted gene delivery to cochlear cell populations and developing innovative genetic cargo designs for inherited and acquired forms of hearing loss.

A substantial portion of this role involves hands-on animal research, including mouse models of acquired hearing loss, cochlear microsurgery, therapeutic delivery, and auditory functional testing. The position offers a unique opportunity to gain expertise across multiple disciplines, spanning gene therapy, synthetic biology, high-throughput screenings, and translational therapeutic development.

Dr. Ergin brings experience from both academia and industry, providing valuable mentorship for trainees interested in academic careers, industry positions, or entrepreneurial ventures. Postdoctoral fellows will be encouraged to pursue independent funding opportunities, including NIH K99/R00 awards and other career development mechanisms.

What will you be doing in this role?

The Project Scientist works independently and in cooperation with the Principal Investigator to make significant and creative contributions to a research or creative project in any academic discipline. The Project Scientist may be an ongoing member of a research team or may be employed for a limited period of time to contribute high-level skills to a specific research or creative program. Project Scientists are not required to carry out independent research or to develop an independent research reputation and do not have teaching responsibilities. Ordinarily, the Project Scientist title will carry out research or creative programs as well as administration of day-to-day lab operations with supervision by a member of the Professorial Series.

Primary Duties & Responsibilities
  • May assist in preparation of grant proposals, submissions, publications and presentations but is not responsible for generating grant funds.
  • May serve as PI for certain grants as approved by supervising member of the Professorial Series.
  • May participate in publications and presentations as author or co-author.
  • May develop, adapt and implement new research techniques and protocols.
  • Assists in lab experiments.
  • Analyzes, interprets, summarizes and compiles data.
  • May lead or train Staff Research Associates and Research Fellows.
  • Will assist in day-to-day laboratory activities.
  • Experience with mouse breeding, colony management, husbandry, and experimental planning
  • Appointees on an academic trajectory will be expected to commit a portion of their time to developing an independent range of research.


Qualifications

Education, Experience & Skills Requirements:
  • PhD, MD, MD/PhD, VMD, AuD or equivalent doctoral degree.
  • Postdoctoral experience in inner ear research, preferred.
  • Experience performing auditory function tests, including ABR and DPOAE in mice, preferred.
  • Hands-on experience with cochlear injection techniques, preferred.
  • Experience working with mouse models under IACUC-approved protocols, preferred.
  • Experience with acquired hearing loss mouse models is a plus.

About Cedars-Sinai

Cedars-Sinai is a non-profit academic medical center located in Los Angeles, California. It is one of the largest hospitals in the United States, with over 1,000 beds and 2,000 physicians. Cedars-Sinai is known for its high-quality patient care, cutting-edge research, and innovative medical education programs. The hospital has been ranked as one of the best in the country by U.S. News & World Report, and has received numerous awards and accolades for its clinical excellence and research achievements. Cedars-Sinai is affiliated with the David Geffen School of Medicine at UCLA and is a member of the Cedars-Sinai Health System.
Learn more about Cedars-Sinai
Size
13,000 employees
Industry
Founded
1902

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