Regeneron Pharmaceuticals, Inc

Manager, Applied AI, Advanced Informatics

Regeneron Pharmaceuticals, Inc$150K — $245K *
Healthcare
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in Computer Science, Machine Learning, Data Science, Biomedical Informatics, Statistics, or related field required; Master's or Ph.D. preferred.
  • 4-6 years of applied AI/ML experience with a strong ability to develop and evaluate models independently.
  • In-depth knowledge of ML theories including supervised and unsupervised learning, deep neural networks, and modern frameworks like PyTorch or TensorFlow.
  • Proficiency in Python and the scientific ML stack, including scikit-learn and NumPy.
  • Experience with NLP or multimodal models, focusing on fine-tuning and prompt engineering with large language models.

Responsibilities

  • Design and develop AI/ML solutions for health informatics use cases, from data exploration to model evaluation.
  • Translate clinical informatics challenges into AI/ML problem statements with clear success criteria.
  • Build and maintain ML pipelines, collaborating closely with production engineering.
  • Conduct experiments and benchmarking studies to validate model performance.
  • Integrate models into informatics workflows by partnering with clinical informaticists and data engineers.
  • Stay updated on advancements in foundation models and their applications in health data.
  • Communicate model limitations and performance clearly to diverse stakeholders.

Benefits

  • Remote work flexibility and on-site options in various NY locations.
  • Opportunity to contribute to research documentation and external publications.
  • Collaborative environment interacting with clinical and engineering teams.
  • Chance to work with cutting-edge advancements in AI/ML and healthcare.
Full Job Description
Manager, Applied AI is a research-facing technical role within the Advanced Informatics team responsible for designing and developing applied AI solutions across health data systems and analytical pipelines. This role works closely with senior applied AI leaders to formulate ML problems against complex health data, validate methods against clinical ground truth, and build reusable analytical capabilities that the broader informatics team depends on.

The ideal candidate brings solid grounding in AI/ML theory, hands-on experience applying it to real-world data problems, and is excited to deepen their expertise at the intersection of machine learning and health informatics.

When & where:
This can be a remote position in the US or on-site position at our Tarrytown, NY, Armonk, NY or Warren, NJ offices.

Discover your role:
  • Design and develop applied AI/ML solutions for health informatics use cases, from problem framing and data exploration through model development and evaluation.
  • Translate business and clinical informatics challenges into well-scoped AI/ML problem statements with clear success criteria.
  • Build and maintain ML pipelines including data ingestion, feature engineering, model training, and evaluation, in close collaboration with production engineering.
  • Conduct experiments, benchmarking, and ablation studies to validate model performance and inform modeling decisions.
  • Partner with clinical informaticists, data engineers, and production AI/ML engineers to integrate models into informatics workflows.
  • Stay current with advances in foundation models, LLMs, retrieval-augmented generation, and their application to biomedical and health data domains.
  • Contribute to research documentation, internal technical reports, and where appropriate, external publications or conference presentations.
  • Communicate model behavior, limitations, and performance clearly to both technical and non-technical stakeholders.


This role requires:

Bachelor's degree (BS) in Computer Science, Machine Learning, Data Science, Biomedical Informatics, Statistics, or a closely related field required. Ph.D. or Master's degree strongly preferred given the research-facing nature of this role.

Minimum Years of Experience: 4-6 years of progressive experience in applied AI/ML, with demonstrated ability to independently develop and evaluate models. Ph.D. graduates with relevant research experience may be considered at the lower end of this range.

Knowledge, Skills & Abilities (Required):
  • Solid understanding of supervised, unsupervised, and self-supervised learning; deep neural networks; and modern ML frameworks (PyTorch, TensorFlow, or equivalent).
  • Strong command of Python and the scientific ML stack (scikit-learn, HuggingFace Transformers, pandas, NumPy, etc.)
  • Experience designing and evaluating NLP or multimodal models, including fine-tuning or prompt engineering with large language models.
  • Proficiency with experiment tracking, model versioning, and reproducible research practices (MLflow, W&B, DVC, or similar).
  • Familiarity with cloud-based ML infrastructure (AWS SageMaker, GCP Vertex AI, Azure ML, or equivalent).
  • Ability to drive technical work independently and communicate findings clearly across teams.

Knowledge, Skills & Abilities (Preferred):
  • Experience with health or life sciences data - EHR/EMR records, claims data, clinical notes, genomic data, or imaging.
  • Informatics domain knowledge (strong plus): familiarity with medical terminologies and ontologies (SNOMED CT, ICD-10/11, LOINC, RxNorm, OMOP CDM) and machinable health data standards.
  • Published work or open-source contributions in applied ML, NLP, or computational biomedicine.
  • Experience with MLOps pipelines, CI/CD for ML, and model observability in production environments.
  • Familiarity with federated learning, privacy-preserving ML, or working with data use agreements in regulated environments.

Salary Range (annually)
$150,500.00 - $245,500.00

About Regeneron Pharmaceuticals, Inc

Regeneron Pharmaceuticals is a biopharmaceutical company that discovers, develops, and commercializes pharmaceutical products for the treatment of serious medical conditions. The Company has therapeutic candidates in clinical trials for the potential treatment of cancer, eye diseases, and inflammatory diseases, and has preclinical programs in other diseases and disorders. The company’s product portfolio includes EYLEA, an aflibercept injection; ARCALYST, a rilonacept Injection for subcutaneous use; ZALTRAP for metastatic colorectal cancer; trap fusion proteins; and fully human monoclonal antibodies. On March 26, 2012, it was announced that Sanofi and Regeneron are in development with a new cholesterol drug which will help reduce cholesterol up to 72%. Regeneron Pharmaceuticals was founded in 1988 and is currently headquartered in New York, USA.

Regeneron Pharmaceuticals, Inc Careers

Join the innovative team at Regeneron Pharmaceuticals, Inc, a leading biotechnology company renowned for its commitment to science-driven solutions. This is an unparalleled opportunity to advance your career with a company at the forefront of medical breakthroughs and clinical research.

Work You’ll Do

At Regeneron Pharmaceuticals, Inc, you will collaborate with some of the brightest minds in the industry, engaging in work that directly contributes to the health and well-being of populations globally. Our diverse team of professionals is dedicated to pioneering developments in biotechnology through continuous innovation and rigorous research.

Explore Job Opportunities and Growth

Regeneron offers a variety of job opportunities that encourage professional growth and personal achievement. Whether you're seeking an entry-level position or a more senior role, you will find a path that aligns with your career ambitions and skills. Our supportive culture emphasizes leadership development and diversity training, ensuring every team member can thrive.

Internship Programs

Kickstart your career with a Regeneron internship. Our programs provide invaluable industry experience, mentoring from seasoned professionals, and opportunities to develop skills that are crucial in the biotech field. Interns at Regeneron gain hands-on experience, contributing to projects that matter.

Benefits and Culture

Choosing to work at Regeneron Pharmaceuticals, Inc means choosing a career that comes with competitive benefits designed to support you both professionally and personally. We offer comprehensive health benefits, retirement plans, and wellness programs. Our inclusive culture fosters an environment where every employee can flourish, driven by collaboration and mutual respect.

Innovation and Leadership

Lead the way in biotechnological innovation with Regeneron. Our leadership is constantly looking towards the future, investing in cutting-edge technology and research that pave the way for medical advancements. At Regeneron, leadership and innovation go hand in hand, creating a dynamic where breakthroughs are common.

Networking and Professional Development

Enhance your professional network and skill set through Regeneron’s extensive networking opportunities and ongoing professional development programs. We believe in nurturing our talent with advanced training sessions and regular workshops that cover the latest trends and technologies in the biotech industry.

Join Our Team

Discover the impact you can make in a career at Regeneron Pharmaceuticals, Inc. Search for open positions that match your skills and interests. We are continuously hiring and looking for passionate, curious, and innovative team players.

Stay Connected

Keep up to date with the latest at Regeneron by following our careers blog. Gain insights from the experts and learn more about the exciting world of biotech at Regeneron Pharmaceuticals, Inc.

Prepare for Your Interview

Ready to join us? Prepare your resume and refine your interview skills to become part of a company that’s dedicated to changing lives. Personalize your job search and get tailored job alerts directly to your inbox, so you never miss an opportunity to be part of our team. At Regeneron Pharmaceuticals, Inc, your career is poised for tremendous growth and innovation. Explore the opportunities today and be part of a team that’s shaping the future of biotechnology.
Learn more about Regeneron Pharmaceuticals, Inc
Size
10,368 employees
Market Cap
$78.1 billion
Industry
Net Income
$3.5 billion
Founded
1988
5 Year Trend
+27%
Revenue
$8.4 billion
NASDAQ

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