About the roleWe're hiring a
Lab Manager to keep our lab running and to run science in it. This is a hybrid role: roughly half lab operations (safety, inventory, purchasing, equipment, SOPs) and half hands-on research (automated high-throughput screening, cell-based assays and protocol development).
You'll own the lab's day-to-day health - EH&S, ordering, vendor and facilities issues - while also serving as the go-to person for our liquid-handling automation and running screens that feed the Drug-Gene Atlas. It's a great fit for someone who loves the bench but is equally energized by making a lab work well for everyone in it.
What you'll doLab operations- Serve as the lab's EH&S lead: maintain safety programs, chemical and biohazard waste, training records, and inspections, and onboard new lab members.
- Manage inventory and purchasing in Quartzy, including project tagging, stock levels for reagents, consumables, and compounds, and vendor relationships.
- Review and approve lab bills in Bill.com within your approval scope, and help track lab spend against budget.
- Coordinate equipment maintenance, service contracts, and repairs; submit and follow up on facilities work orders.
- Write, maintain, and enforce lab policies and SOPs; keep the lab organized, clean, and audit-ready.
- Report on lab status, issues, and improvement ideas to leadership.
Research and automation- Run and troubleshoot automated workflows on liquid-handling systems (e.g., Hamilton STARlet) for high-throughput compound screening in 384-well format.
- Transfer manual protocols - cell culture, genomics, cell-based assays - onto automated platforms, optimizing for reproducibility, throughput, and data quality.
- Design and run validation experiments for new or updated automated protocols.
- Support screens and disease-modeling work, including iPSC-derived cell types (e.g., neurons, astrocytes) and fibroblasts, from plating through sample prep for sequencing.
- Document protocols, validation results, and technical guides; train scientists and new hires on instruments and methods.
- Evaluate and recommend new automation tools and lab technologies.
QualificationsRequired- BS or MS in biology, molecular biology, biotechnology, or a related field.
- 3+ years of hands-on lab experience in biotech or academic research, including cell culture and molecular or cell-based assays (e.g., qPCR, NGS library prep, imaging or functional assays).
- Experience running and troubleshooting automated liquid handlers (Hamilton, Tecan, Agilent, or similar).
- Lab operations experience: ordering and inventory, safety compliance, equipment upkeep, and SOP writing.
- Highly organized, detail-oriented, and comfortable switching between operations and bench work in a fast-paced startup.
- Clear written and verbal communication; proactive about raising issues.
Preferred- Familiarity with high-throughput screening, iPSC-derived cells, or transcriptomics workflows (e.g., DRUG-seq, RNA-seq).
- Formal EH&S responsibility or training (biosafety, chemical hygiene, hazardous waste).
- Familiarity with Quartzy, Benchling, and Bill.com.
- Experience designing validation studies and working with large datasets.
Pay range: $100,000-$105,000 annually
