Summit Therapeutics plc

Director, Program Management

Summit Therapeutics plc$190K — $237K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree with 12 years of relevant experience; MS/MBA with 10 years; PhD/PharmD/DVM/MD with 6+ years.
  • 10-12+ years of pharmaceutical/biotech industry experience in program management.
  • Extensive experience in pharmaceutical drug development, particularly solid tumor oncology.
  • Proven track record of leading complex, global programs and influencing senior executives.
  • Strong communication and presentation skills; proficient in program management tools.

Responsibilities

  • Drive execution across multiple development programs to meet objectives.
  • Collaborate with executive leadership on strategy and program alignment.
  • Define major milestones and decision points across programs.
  • Lead scenario planning and decision frameworks for executive support.
  • Ensure cross-functional alignment across Development, Regulatory, and Manufacturing.
  • Present program status and insights clearly to C-suite and senior leaders.
  • Identify program risks and continuous improvement opportunities.

Benefits

  • Opportunity to lead strategic and operational initiatives in a growing company.
  • Mentorship and development opportunities for aspiring program managers.
  • Engagement with executive leadership and high-level decision-making processes.
  • Access to high-impact projects in the pharmaceutical industry.
  • Dynamic and fast-paced work environment with potential for significant contribution.
Full Job Description
Overview

The Director of Program Management provides strategic and operational leadership across multiple development programs, driving alignment between Research, Development, Business Strategy, Manufacturing, and execution. This role plays a critical part in advancing collaboration programs across the portfolio and enabling long-term value creation from development through regulatory approval.

The Director serves as the primary point of contact for key programs to executive leadership, ensures disciplined program governance, and strengthens the Program Management function as the organization scales. This position reports to the VP, Program Management and may have people leadership responsibility.

Role and Responsibilities

Strategic Program Leadership
  • Responsible for overall execution of multiple programs to deliver on program objectives and maximize value.
  • Partner with executive leadership on program, strategy,
  • Define and oversee major milestones, decision points, objectives, and inflection points across programs
  • Lead scenario planning, trade-off analyses, and decision frameworks to support executive decision-making
  • Ensure alignment across Development, Regulatory, Manufacturing, and Corporate Strategy


Cross-Functional & Executive Leadership
  • Lead and integrate complex cross-functional workstreams across Research, Development, Regulatory, and Manufacturing
  • Facilitate effective decision-making and accountability across global teams and external partners, in collaboration with Alliance Management.
  • Present clear insights, recommendations, and program status to C-suite and senior leadership
  • Mentor and develop Program Managers and strengthen organizational capability

Program Execution & Governance
  • Oversee end-to-end program execution, including activation of new indications post-Go decision
  • Ensure consistent application of program management standards, dashboards, and governance models
  • Chair timely, efficient, and action-oriented team meetings to coordinate operations and communications.
  • Review and validate integrated program plans, timelines, and metrics for accuracy and strategic alignment
  • Represent Program Management on senior governance forums and key internal or external teams


Timelines & Scenario Planning
  • Oversee integrated program timelines aligned with enterprise goals
  • Partner with functional leaders on budgets and forecast planning
  • Ensure data integrity and transparency in executive reporting


Risk, Opportunity & Continuous Improvement
  • Identify and manage program risks and mitigation strategies
  • Communicate risks, opportunities, and trade-off s clearly to executive leadership
  • Drive continuous improvement of program management processes, tools, and operating models
  • Lead strategic initiatives to mature the Program Management function as the company grows
  • All other duties as assigned

Experience, Education and Specialized Knowledge
  • Bachelor's degree and minimum 12 years of relevant project management/scientific experience within the pharmaceutical industry; OR a MS or MBA and minimal 10 years of relevant experience; OR a PhD in a scientific field or a PharmD, DVM or MD degree with 6+ years of relevant experience
  • 10-12+ years of pharmaceutical or biotech industry experience with progressive responsibility in program or portfolio management
  • Extensive pharmaceutical drug development experience required;
  • Prior solid tumor oncology experience, including late-stage development and registrational trials, required
  • Demonstrated success leading complex, global, cross-functional programs and influencing senior executives
  • Experience with managing alliances and external partners strongly preferred
  • Proven ability to balance strategic leadership with operational execution
  • Exceptional communication, facilitation, and presentation skills
  • Strong proficiency in program management and planning tools (e.g., MS Office, Project, Smartsheet)
  • Willing to travel for key meetings.


This is the pay for this position

Pay Transparency

$190,000-$237,000 USD

Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit's Talent Acquisition team at [email protected] to obtain prior written authorization before referring any candidates to Summit.

About Summit Therapeutics plc

Summit Therapeutics is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to treat rare diseases with high unmet medical need. The company's lead product candidate, Ridinilazole, is a precision antibiotic that has the potential to treat Clostridium difficile infection (CDI) with a superior clinical profile compared to existing CDI treatments. Summit Therapeutics is also developing a pipeline of additional product candidates targeting genetic diseases and other indications.
Learn more about Summit Therapeutics plc
Size
105 employees
Market Cap
$842.6 million
Industry
Founded
2003
5 Year Trend
+9910%
Revenue
$1 million
NASDAQ

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