Director, Machine Learning, Virtual Cell Initiative

Arc Institute

$150K — $200K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Computational Biology, Bioinformatics, Machine Learning, or related field.
  • Minimum of 5 years' experience in machine learning, familiar with frameworks like Pytorch, TensorFlow, JAX.
  • Proven experience in leading research teams in multi-disciplinary settings.
  • Strong interest or experience in biology, with skills for effective communication with biologists and ML engineers.
  • Excellent communication abilities, both written and verbal, demonstrated by a strong record of presentations and publications.

Responsibilities

  • Lead and build a team of 6 ML research scientists and engineers, including students.
  • Engage in active collaboration with wet lab scientists to enhance a diverse single cell training data set.
  • Work with research groups to integrate various omics data beyond scRNA-seq and Perturb-seq.
  • Stay updated on cutting-edge ML research and innovate new architectures.
  • Aim to create a high utility virtual cell model for global use by biologists.
  • Foster a collaborative and inclusive team culture, sharing expertise and mentoring.
  • Attract top talent to support the virtual cell initiative goals.

Benefits

  • Opportunity to lead a multidisciplinary team.
  • Access to vast datasets for innovative modeling.
  • Collaboration with leading experts in AI and biology.
  • Emphasis on a culture of inclusion and continuous learning.
  • Chance to publish and impact scientific progress globally.
Full Job Description
About the position

We are searching for an innovative scientific leader experienced in building predictive models based on single-cell genomic data. The chosen candidate will spearhead the development and application of advanced machine learning models tailored for perturbative gene expression modeling, in the context of Arc's virtual cell initiative.

About you
  • You are passionate about machine learning, ideally with experience or strong interest in biology and single-cell genomics.
  • You want to develop highly innovative and accurate biology-inspired multimodal machine learning models.
  • You are excited about collaborating with a multidisciplinary team of computational and experimental biologists at Arc.
  • You are a strong communicator, capable of translating complex technical concepts at the intersection of machine learning and biology.
  • You are a continuous learner.
  • You are interested in recruiting and managing your own group of scientists and engineers as well as mentoring and training for other scientists.

In this position you will
  • Lead/build a team of 6 ML research scientists and engineers augmented with undergrad/masters/PhD students to contribute to the development of a state-of-the-art foundation model and agentic framework for understanding how cells respond to perturbations.
  • Work in an active learning loop with Arc's wet lab scientists to shape the world's largest and most diverse set of single cell training data across many cell contexts.
  • Collaborate closely with other research groups to integrate genomics, functional track,and omics data more broadly beyond scRNA-seq data and Perturb-seq
  • Stay up to date on the latest in frontier ML research and pioneer new architectures and approaches.
  • The ultimate goal is to build a high utility virtual cell model for use by biologists worldwide. We publish our breakthroughs to widely accelerate scientific progress and partner with some of the biggest names in AI.
  • Commit to a collaborative and inclusive team environment, sharing expertise and mentoring others.
  • Attract the very best talent in the world to support VCI initiative goals

Requirements
  • PhD in Computational Biology, Bioinformatics, Machine Learning, or a related field.
  • Minimum of 5 years of experience working in/with machine learning, well versed in frameworks such as Pytorch, TensorFlow, JAX, etc.
  • Proven experience leading research teams in a fast paced, multi-disciplinary environment.
  • Experience with or strong interest in biology with ability to communicate and collaborate successfully with biologists and pure ML engineers.
  • Excellent communication skills, both written and verbal, with a strong track record of presentations and publications.

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