Incyte

Director, Antibody Discovery

Incyte$140K — $180K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. in biochemistry, molecular biology, cell biology, or related field with relevant antibody discovery experience.
  • Hands-on expertise in antibody discovery utilizing hybridoma, single cell B cloning, or display technologies.
  • Experience with immunization methods to enhance responses to difficult antigens is preferred.
  • Familiarity with antibody optimization and characterization processes.
  • Strong background in molecular biology and bioinformatics is essential.
  • Proven ability to collaborate effectively within diverse teams.
  • Demonstrated experience in leading and managing scientific groups.

Responsibilities

  • Lead antibody discovery efforts using immunization and display technologies.
  • Direct and manage external collaborations for biotherapeutic compound discovery and optimization.
  • Establish and oversee new technology platforms for antibody discovery.
  • Collaborate with immunologists and pharmacologists on target validation and discovery programs.
  • Utilize CROs and internal resources to enhance discovery processes through collaboration.
  • Manage a scientific team focused on antibody discovery and technology development.
  • Set and manage ambitious timelines across multiple discovery projects.
  • Act as an in-house specialist for Due Diligence processes.
  • Implement next-generation sequencing (NGS) platforms for antibody discovery.

Benefits

  • Opportunity to lead cutting-edge antibody discovery projects.
  • Access to advanced technology platforms for biotherapeutic research.
  • Collaboration with leading experts in immunology and pharmacology.
  • Supportive environment for scientific innovation and discovery.
  • Role in shaping the future of antibody therapeutics through managerial and operational responsibilities.
Full Job Description
Overview

Job Summary (Primary function)
The Director, Antibody Discovery implements, develops, and operates the antibody discovery platforms. The position directs the discovery of therapeutic and tool antibody campaigns, operate as project or technology leader on Biotherapeutic Research campaigns, and participate as a key resource on managing and supporting external collaborations.

Essential Functions of the Job (Key responsibilities)
• Lead antibody discovery using immunization and/or display technologies.
• Direct external collaborations for the discovery and optimization of biotherapeutic compounds
• Support the establishment and management of new technology platforms for antibody discovery.
• Collaborate with immunologists and pharmacologists to drive target validation and discovery programs.
• Utilize Contract Research Organizations (CROs) and internal resources for optimizing discovery processes, ensuring inclusivity and collaboration across diverse teams.
• Manage a team of scientists supporting Ab discovery and technology development.
• Establish and manage ambitious timelines for multiple discovery projects.
• Participate as an in-house specialist in Due Diligences.
• Responsible for NGS platform implementation for Ab. Discovery.

Qualifications (Minimal acceptable level of education, work experience, and competency)
• Advanced degree (Ph.D.) in biochemistry, molecular biology, cell biology, or related field, plus relevant experience in antibody discovery.
• Extensive knowledge and hands-on experience in antibody discovery using hybridoma, single cell B cloning and/or display technologies for the discovery of antibodies and antibody fragments.
• Experience with immunization approaches for enhancing immune responses to challenging antigens is desired.
• Experience in antibody optimization/characterization is preferred.
• Extensive knowledge of molecular biology and bioinformatics.
• Demonstrate ability to work in a highly collaborative team environment.
• Experience leading a diverse scientific team.
• Experience managing a scientific group

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

About Incyte

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of proprietary therapeutics. The company was founded in 1991 and is headquartered in Wilmington, Delaware. Incyte's main focus is on oncology, inflammation, and autoimmunity. The company's flagship product, Jakafi, is a JAK1/JAK2 inhibitor used to treat myelofibrosis and polycythemia vera. Incyte has a number of other products in development, including itacitinib, a JAK1 inhibitor for the treatment of graft-versus-host disease, and pemigatinib, a FGFR inhibitor for the treatment of cholangiocarcinoma.
Learn more about Incyte
Size
2,094 employees
Market Cap
$17.6 billion
Industry
Net Income
-$295.7 million
Founded
1991
5 Year Trend
+22%
Revenue
$2.6 billion
NASDAQ

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