Principal Scientist, Data Science and AI - Princeton, NJ

dsm-firmenich • $180K — $260K *
Healthcare
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • PhD in a quantitative field like Computational Biology or Bioinformatics with 10+ years of relevant experience.
  • Expertise in human molecular biology leveraging multi-omics and microbiome data.
  • Experience with large-scale cohort data and real-world evidence challenges.
  • A strong track record in leading successful R&D or clinical programs resulting in product launches.
  • Proficient in Python/R and building production-grade analytical frameworks.
  • Innovative thinking regarding Large Language Models (LLMs) for knowledge extraction.
  • Understanding metadata management for longitudinal research is a plus.

Responsibilities

  • Direct the development of scalable data pipelines for large human cohort datasets.
  • Establish multi-criteria scoring systems utilizing AI/ML for ingredient prioritization.
  • Oversee the creation of robust scientific evidence packages for data outputs.
  • Serve as a strategic partner across Data Science and other research teams.
  • Champion the use of advanced AI tools to transform knowledge synthesis.
  • Mentor junior data scientists to promote systems thinking and code reusability.

Benefits

  • Variety of projects and data types fostering continuous learning.
  • Collaborative and open-minded team environment.
  • Support for unique career paths across health, nutrition, and beauty sectors.
  • Opportunity to make a significant impact on consumer health and sustainability.
Full Job Description
Principal Scientist, Data Science and AI

Location: Princeton, NJ

We are seeking an accomplished Principal Scientist to serve as a technical cornerstone for our Data Science and AI initiatives. With a deep mastery of multimodal and multiomics data, strong expertise in clinical practice and human health metrics, you will design a world-class R&D engine that systematically mines internal and external datasets to generate evidence for human nutrition and care.

Your Key Responsibilities:
  • Architectural Vision: Direct the development of scalable pipelines for the ingestion and harmonization of massive, heterogeneous human cohort datasets. Lead the design and implementation of a standardized analytical framework that integrates high-dimensional data (diet, lifestyle, host-microbiome omics, and clinical outcomes).
  • Decision Frameworks: Establish AI/ML-assisted multi-criteria scoring systems to prioritize ingredients based on novelty, biological relevance, and commercial viability.
  • Evidence Orchestration: Oversee the creation of comprehensive scientific evidence packages, ensuring that every data science output is grounded in biological plausibility and robust enough to withstand clinical scrutiny.
  • Cross-Functional Influence: Act as a key strategic partner to other Data Science groups, Life Science and other research organizations, as well as the business unit of Health Nutrition and Care. Ensure data science is integrated into the earliest stages of experimental design.
  • Innovation Catalyst: Champion the adoption of state-of-the-art AI tooling, including Generative AI and Large Language Models (LLMs), to revolutionize how the organization synthesizes knowledge and generates novel hypotheses.
  • Mentorship: Provide technical mentorship to junior data scientists, fostering a culture of systems-oriented thinking and code reusability.


We Offer:
  • A broad variety of projects, data types, and statistical approaches, ensuring you never stop learning and can apply a wide range of methods.
  • A team of diverse, open-minded colleagues who aren't afraid to think outside the box and challenge the status quo.
  • A truly global and collaborative team environment that cares about our employees' experience and growth.
  • Unique career paths across health, nutrition and beauty - explore what drives you and get the support to make it happen.
  • A chance to impact millions of consumers every day - sustainability embedded in all we do.


You Bring:
  • PhD in Computational Biology, Bioinformatics, Biostatistics, Epidemiology or a related quantitative field with 10+ years of post-doctoral experience (predominantly in an industrial R&D setting).
  • Expert-level command of human molecular biology, with a focus on leveraging processed multi-omics and microbiome data for advanced analytics.
  • Familiarity with large-scale cohort data and the challenges of working with real-world evidence
  • Proven history of leading high-impact discovery, translational science programs and/or clinical programs that resulted in successful product launches or major scientific breakthroughs.
  • Deep expertise in Python/R and with a track record of building production-grade analytical frameworks.
  • A forward-thinking approach to using Large Language Models (LLM) for scientific knowledge extraction and automated hypothesis generation.
  • Understanding of metadata management and harmonization frameworks for large-scale longitudinal research data is a plus.
  • Comfortable operating at the complex intersection of data science & AI, human biology, and global research and development. Capable of distilling high-dimensional technical complexity into a clear, persuasive narrative for non-technical stakeholders.


The salary or hourly wage scale provided reflects the pay range dsm-firmenich expects to pay the successful candidate for the position. Individual pay offered will be based on the applicant's job-related skills, experience, relevant education, or training, and primary work location. This position is also eligible for bonuses and benefits, which are not included in the pay scale provided. Salary $180,000 -$260,000.

The application process

Interested in this position? Please apply online by uploading your resume in English by April 3, 2026.

Agency statement

We're managing this search directly at dsm-firmenich. If you're applying as an individual, we'd love to hear from you. We're not accepting agency submissions or proposals involving fees or commissions for this role

About dsm-firmenich

DSM-Firmenich Careers

There has never been a more opportune time to join the global team at DSM-Firmenich—the leading innovators in the realm of sensory and nutritional solutions. This company stands as a beacon of innovation, sustainability, and growth in the industry.

Work You’ll Do

Join DSM-Firmenich’s market-leading team to assist some of the most renowned companies in mastering their journey through sensory and nutritional innovation. Transform businesses and entire sectors with the brightest minds at DSM-Firmenich, leveraging a unique position in the marketplace at the intersection of science, technology, and market needs. Lead in a distinctive role, combining deep industry expertise with digital innovation to drive significant market advancements. Engage with a global team of business and technology advisors to help clients navigate their transformation journeys in the sensory and nutrition sectors. Collaborate with a vast network of professionals—dedicated to pushing the boundaries of what's possible in taste, nutrition, and health.

Introducing the DSM-Firmenich Innovation Hub

The team is constructing a leading-edge Innovation Hub to guide some of the world’s most prominent companies through their transformation journeys, utilizing groundbreaking solutions.

Do Innovative Work

Be part of the largest group of sensory and nutritional experts in the world, delivering targeted solutions through a depth and breadth of consulting experience and innovation that’s unparalleled.

Be Part of a Great Team

Work on a wide range of projects utilizing DSM-Firmenich’s technology and harness the capabilities, global scale, and joint solution development of a team that’s committed to redefining the industry.

Future-Proof Your Career

Advance your career with limitless opportunities supported by unmatched training, development, and certification support. Go as far as your ambition can take you in an environment that fosters professional growth and leadership development.

Explore Job Opportunities

From job opportunities in innovative fields to internships that offer real-world experience, DSM-Firmenich provides a platform for growth and professional development. The company values diversity and is committed to providing comprehensive benefits and diversity training to support its team members.

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This network’s combined service capabilities and global scale help clients overcome challenges and lead transformation in their industries. Clients globally turn to DSM-Firmenich for new strategies and solutions that drive innovation and growth in the digital era.

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