Position Summary The Buck Institute's Clinical Research Core is looking for an organized, motivated clinical research leader to run the in-person visits for THRIVE and serve as the operational heart of our on-site clinic.
THRIVE is the clinical validation arm of PROSPR, an ARPA-H-funded program working to design the first FDA registration trial for a gerotherapeutic. THRIVE is developing the aging-relevant outcome measures such a trial would rely on, seeing how they perform with real participants, and testing them in a YMCA-guided lifestyle intervention.
Key ResponsibilitiesTHRIVE Study Leadership (~50%)
- Lead day-to-day execution of THRIVE in line with the protocol, GCP, ICH guidelines, and Buck Clinical Research SOPs.
- Translate the protocol into participant flow and scheduling across the clinic and community sites, adapting quickly when one change affects staff, rooms, and equipment at once.
- Lead a team of two senior and two junior research associates who collect data at community locations 2-3 days per week.
- Partner with the Recruitment Specialist to keep enrollment on pace; track milestones and flag risks to study leadership.
- Own IRB compliance (continuing reviews, amendments, documentation), data quality and query resolution, biospecimen tracking, and protection of participant PHI and sponsor confidential information.
- Run THRIVE team meetings, implement protocol amendments, and manage relationships with consortium partners, collaborators, and vendors while keeping stakeholders informed.
Clinic Management (~50%)
- Be the clinic's quarterback: stay on top of visits, staff coverage, and emerging issues across all studies, and resolve bottlenecks, coverage gaps, role confusion, and conflicts before they affect participants or data.
- Oversee procedure quality by observing procedures and reviewing source documentation.
- Oversee safety reporting and escalation for adverse events, serious adverse events, adverse events of special interest, and protocol deviations, including corrective and preventive actions.
- Lead, mentor, and train Clinical Research Associates; balance workloads, provide feedback, and maintain the SOP library and training records.
- Serve as first point of contact for staff, collaborators, and participants, and coordinate with study medical staff, study leaders, and project managers.
- Manage clinical equipment, supplies, biospecimen inventory and LIMS, clinical space, and vendors for lab analysis and other services.
- Support new-study intake with operational reviews and budget inputs, and coordinate participant payments with finance.
- Pitch in on study visits, sample processing, and data entry as needed; help improve clinic practice; and promote cultural respect and multilingual recruitment.
QUALIFICATIONS
Education & ExperienceOne of the following in clinical research or project management in a biomedical or clinical research setting:
- High school diploma/technical degree and 8+ years of experience
- Bachelor's degree and 4+ years of experience i
- Master's or PhD degree and 2+ years of experience
Skills- Clinical skills/background sufficient to train, mentor, and oversee quality for study staff performing clinical procedures
- Supervisory or team leadership experience
- Experience preparing or submitting IRB protocols, amendments, or continuing reviews
- Strong organization across concurrent studies and priorities, with reliable follow-through, initiative, and proactive problem-solving
- Excellent written, verbal, and interpersonal communication; comfortable working independently, as part of a team, and with all levels of management
- Attention to deadlines and budgetary guidelines
Nice to have- Professional certification such as PMP, ACRP-CP, SOCRA CCRP, or equivalent
- Experience with project management software (e.g., Wrike, MS Project) and EDC systems (e.g., REDCap)
- Phlebotomy certification/experience
- Clinical research experience in a non-profit/academic setting
Compensation & Job Details- Full-time, 40 hours per week, onsite. You'll be available in person or on call during clinic visit hours (7:30 am - 2:00 pm)
- Salary: $90,000 - $100,000 / year commensurate with experience
- Benefits include health insurance, paid parental leave, PTO, and a 401(k) with 5% employer match
How to applyClick APPLY to submit your resume and a cover letter telling us why you're a great fit for this role.
