Exelixis

AI and Agentic Engineer II

Exelixis$152K — $215K *
Information Technology
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's or Master's degree in a relevant field, plus 3-5 years of related experience.
  • 2-4 years of hands-on experience in AI applications or automation.
  • Intermediate to advanced proficiency in Python and/or JavaScript/TypeScript.
  • Intermediate proficiency with agent frameworks and APIs.
  • Intermediate understanding of security best practices and data governance.
  • Intermediate experience with cloud AI platforms like AWS.
  • Effective written and verbal communication skills.

Responsibilities

  • Design and implement production-grade agentic applications and workflows.
  • Transform prototypes into robust, production-ready services with detailed specifications.
  • Integrate various tools and data sources into agentic applications.
  • Establish CI/CD pipelines, observability, and automated testing for AI workloads.
  • Produce architectural documentation and support operability of AI solutions.
  • Lead technical reviews, threat modeling, and deployment readiness assessments.
  • Advocate for secure-by-design and responsible AI principles and practices.

Benefits

  • Comprehensive employee benefits including medical, dental, and vision coverage.
  • Generous 401k plan with company contributions.
  • Discretionary annual bonus program and stock purchase options.
  • 15 vacation days, 17 paid holidays, and 10 sick days annually.
  • Flexible spending accounts for healthcare or dependent care.
Full Job Description
SUMMARY/JOB PURPOSE

The Engineer II - AI and Agentic is responsible for designing, building, and deploying production-grade agentic applications that automate multi-step IT and business workflows across Exelixis. This role delivers spec-driven, testable, and secure AI solutions, contributes to platform patterns and reusable components, while advancing the engineering standards.

ESSENTIAL DUTIES/RESPONSIBILITIES
  • Design and deliver end-to-end agentic applications and multi-agent workflows that automate IT and business processes.
  • Convert prototypes into hardened, production-ready services with clear specifications, modular design, robust error handling, and comprehensive test coverage.
  • Integrate LLMs, prompts, tools, APIs, and enterprise data sources (e.g., Bedrock, Databricks Mosaic AI, MCP servers) into reliable use cases.
  • Implement CI/CD pipelines, automated evaluation harnesses, observability, and artifact versioning for AI/agent workloads.
  • Author architecture notes, runbooks, SOPs, and technical documentation to support adoption, operability, and maintainability.
  • Lead prompt/spec reviews, code reviews, threat modeling exercises, and release-readiness gates.
  • Apply and evangelize secure-by-design and responsible AI principles, including data governance, privacy, and safe prompting aligned to organizational policy
  • Contribute reusable components, patterns, and internal libraries to the platform
  • Partner with product managers, security, and platform teams to translate business needs into scalable technical solutions
  • Performs other duties as assigned
  • Complies with all policies and standards


SUPERVISORY RESPONSIBILITIES
  • No supervisory responsibilities


EDUCATION/EXPERIENCE/KNOWLEDGE/SKILLS & ABILITIES

Education
  • Bachelor's degree in Computer Science, Artificial Intelligence, Data Science, Software Engineering, or a related field and 5 years of related experience; or
  • Master's degree in Computer Science, Artificial Intelligence, Data Science, Software Engineering, or a related field and 3 year or related experience; or
  • Equivalent combination of education and experience.


Experience
  • 2 - 4 years of relevant experience in AI application, data science, automation, or related technical work, including hands-on experience building or contributing to LLM-enabled applications, agentic workflows, API integrations,


Knowledge, Skills and Abilities

Required:
  • Intermediate to Advanced proficiency in Python and/or JavaScript/TypeScript, including modular design, testing, and packaging.
  • Intermediate proficiency with agent frameworks and agentic patterns: tool use, planning/execution loops, guardrails, evaluation, and prompt/version management.
  • Intermediate proficiency building and consuming REST APIs, and integrating enterprise systems with OAuth/JWT, secrets management, and secure data handling.
  • Intermediate proficiency with CI/CD, automated testing (unit/integration), linting, and observability for AI applications.
  • Intermediate understanding of security best practices, architecture design principles, and responsible AI/data governance.
  • Intermediate communication skills, written and verbal, and demonstrated ability to collaborate with cross-functional stakeholders and mentor junior engineers.
  • Intermediate experience with cloud AI platforms - preferably AWS Cloud, AWS Bedrock, and Databricks Mosaic AI - and vector stores or retrieval-augmented generation (RAG) patterns.
  • Intermediate knowledge of AI-native engineering using Claude Code, Codex, GitHub Copilot, or equivalent coding agents.


Preferred:
  • Experience delivering evaluation frameworks, red-teaming, or LLM observability tooling.


Travel Requirements
  • No travel is required for this position.


#LI-EZ1

Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this position is $152,000 - $215,000 annually. The base pay range may take into account the candidate's geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate's geographic region, job-related knowledge, skills, experience and internal equity, among other factors.

In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

WORKING CONDITIONS:

Our office is a modern space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.

DISCLAIMER:
The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

About Exelixis

Exelixis is a biotechnology company that develops and commercializes innovative medicines for the treatment of cancer. The company's flagship product, CABOMETYX® (cabozantinib), is an inhibitor of multiple tyrosine kinases, including MET, AXL, and VEGFR, which are involved in the growth and spread of cancer cells. CABOMETYX is approved in the United States for the treatment of advanced renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC), and is also approved in the European Union and other countries for the treatment of advanced RCC. Exelixis is headquartered in Alameda, California, and has additional offices in South San Francisco, California, and Basel, Switzerland. Learn more at www.exelixis.com.
Learn more about Exelixis
Size
954 employees
Market Cap
$5 billion
Industry
Net Income
$111.7 million
5 Year Trend
+49.6%
Revenue
$987.5 million
NASDAQ

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