Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Legal Director, Strategic Deals
$206K - $309K *
Engineer impactful strategic partnerships and lead complex negotiations while building a high-performing legal team. Collaborate cross-functionally to drive commercial support for product initiatives...
1 month ago
$173K - $198K *
Lead the evolution of data architecture, driving real-time capabilities and AI integration. Collaborate with executives and teams to enhance data quality, governance, and scalability while mentoring a...
Yesterday
$150K - $190K *
Elevate our field marketing strategy by leading regional initiatives that drive demand for our software. Collaborate with sales teams to create impactful events and programs, while building and managi...
1 week ago
$60K - $125K *
Empower customer success by managing relationships and driving growth through strategic account management, ensuring satisfaction and advancing CloudWave as a trusted IT advisor in healthcare solution...
2 days ago
Director Transmission Engineering
$200K - $250K *
Join a dynamic team as a senior leader to enhance transmission engineering services, oversee project delivery, and strengthen client relationships while driving innovation and growth in the energy sec...
1 week ago
Director, US Oncology Marketing Portfolio Strategy (Customer Engagement)
$190K - $300K *
Manage and optimize the digital marketing strategy for oncology products, enhancing customer engagement through innovative digital assets. Lead cross-functional teams to execute comprehensive marketin...
1 week ago
Senior Manager - APR DRG Concept Development Analyst
$100K - $125K *
Transform healthcare analytics by leading the development of APR-DRG audit criteria. Collaborate with cross-functional teams to enhance payment integrity through data-driven insights and innovative so...
6 days ago
Strategic Accounts Program Manager - Remote
$110K - $130K *
Shape the future of data center projects by managing strategic client relationships, overseeing multi-million-dollar initiatives, and ensuring operational excellence throughout the project lifecycle...
3 weeks ago
Senior Project Manager Product
$110K - $130K *
Shape the future of product development by leading cross-functional teams to deliver innovative solutions from concept to launch, ensuring alignment with business goals and quality standards...
1 week ago
$80K - $95K *
Drive your career forward by overseeing essential accounting activities, ensuring compliance with GAAP and government contracting regulations. Leverage your expertise in financial reporting, general l...
Reposted 3 days ago
$130K - $150K *
Engage with healthcare leaders to drive sales growth and enhance customer relationships. This role focuses on managing the SurgiSmart IQ business, developing new opportunities, and executing strategic...
5 days ago
$90K - $110K *
Empower your career by bridging technical solutions and customer needs in the drive-thru technology space. Collaborate with Sales and Product teams to design and deliver innovative solutions that enha...
2 weeks ago
Growth Account Executive - East
$79K - $109K *
Transform your career by driving new business in the SMB segment. Collaborate with cross-functional teams to articulate cloud security solutions and exceed sales quotas within a dynamic growth environ...
3 weeks ago
$150K - $180K *
Grow your career by driving strategic sales in a dynamic cybersecurity landscape, collaborating with leaders and partners to expand market presence and achieve impressive business growth. Engage with...
Reposted yesterday
Creative Operations Senior Manager (Traffic) - Remote
$90K - $110K *
Join a team that's redefining creative operations! Lead resource management, optimize workflows, and foster collaboration across teams to deliver exceptional creative solutions for clients in a dynami...
1 week ago
$100K - $120K *
Join a team that's redefining content marketing strategies while driving brand authority and customer engagement. Lead innovative projects and manage impactful content across multiple channels to elev...
4 weeks ago
$209K - $273K *
Grow your career with a technical leadership role tackling complex challenges while mentoring others and collaborating on impactful projects across multiple engineering teams, elevating standards and...
3 weeks ago
Sales Director, Aerospace & Defense
$150K - $180K *
Accelerate progress at the forefront of the Aerospace & Defense sector by leading sales initiatives across the Americas and EMEA. Drive growth, build strong teams, and develop strategies to expand mar...
Reposted 3 weeks ago
Internal Communications Manager
$88K - $147K *
Inspire and elevate employee engagement through strategic internal communications. Collaborate with leaders to craft and deliver impactful messaging that drives understanding of company goals and fost...
Reposted 2 weeks ago
Director, Business Development, Sales
$200K - $225K *
Drive growth by identifying and closing enterprise accounts through strategic outreach and relationship building. Manage complex sales cycles and ensure seamless transitions for long-term customer suc...
1 week ago
$100K - $125K *
Lead creative strategy and direction, collaborating with teams to develop impactful brand campaigns. Drive insights from research, enhance client relationships, and contribute to new business initiati...
3 days ago
$102K - $120K *
Lead the charge in driving product strategy and execution for AI applications, ensuring high-quality delivery and alignment with business outcomes. Collaborate with cross-functional teams to optimize...
3 weeks ago
$140K - $229K *
Champion the evolution of an IAM platform by driving product vision, collaborating with cross-functional teams, and ensuring compliance with industry standards while delivering secure, scalable soluti...
3 weeks ago
Senior Complex Claims Consultant / Claims Counsel
$110K - $135K *
Lead the charge in managing high-severity, complex insurance claims, focusing on EPL and Professional Liability. Serve as a subject matter expert, ensuring compliance and strategic resolution while ad...
2 weeks ago
Director, Analytics Engineering
$139K - $285K *
Drive the analytics engineering team to create AI-ready data solutions, ensuring trusted access to data across the organization. Lead strategic initiatives, build self-service capabilities, and foster...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.