The Opportunity
The Department of Structural Biology at Genentech is seeking a cryoEM/cryoET expert to join its cryogenic electron microscopy (cryoEM) team as a System Specialist II and support its mission to enable drug discovery and fundamental research.
Drive structure-based drug discoveryby processing data to deliver high-resolution cryoEM maps for collaborative research teams.
Collaborate closely with interdisciplinary project teamsacross Roche and Genentech to solve complex protein target structures and annotate/analyze in situ tomograms.
Empower and train facility usersacross all workflow stages—from initial sample preparation to advanced data processing.
Operate and maintain cutting-edge instrumentation, including Titan Krios and Glacios microscopes equipped with SelectrisX Falcon4i detectors.
Pioneer continuous improvementby testing, adapting, and adopting emerging protocols, software tools, and technologies for cryoEM/cryoET.
Thrive in a supportive, state-of-the-art research environmentwith centralized high-performance computing, dedicated cell culture spaces, and robust data storage.
Who You Are
Qualified by education:You hold a Bachelor’s degree with 5+ years, a Master’s degree with 3+ years, or a PhD with 0–2 years of relevant experience in biochemistry, biophysics, or structural biology.
CryoET Capable: Hands-on experience with on-grid cell culture, FIB milling, tilt series data collection and related workflows for cryoET
Proficient in cryoEM image processing:You bring a track record of obtaining high-resolution 3D maps and/or tomograms from cryoEM single-particle and/or tilt series data.
Adaptable and eager to grow:You are enthusiastic about expanding your skill set across grid preparation, automated data collection, and facility operations.
Collaborative and organized:You thrive in team environments, bring strong communication skills, and maintain exceptional attention to detail.
Passionate about impact:You are excited to apply structural biology techniques to enable groundbreaking drug discovery and improve patient lives.
Together, we’ll advance along the whole patient journey with the aspiration to prevent, stop and cure diseases.
Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of California is $91,900 - $170,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
