POSITION SUMMARY:
This position is responsible for designing and executing complex experiments and analyzing the resulting data in support of reagent and assay development projects. This is a laboratory-based position to develop methods of purification and biochemical characterization of protein-based reagents.
DUTIES AND RESPONSIBILITIES:
• Independently designs and executes complex experiments and implements plans.
• Analyzes data using spreadsheets and graphing software, including statistical analyses. Prepares clear and concise presentations without supervisor input, including thoughtful summaries and recommendations for next steps. Presents to peer and supervisor review groups.
• Serves as subject matter expert and provides guidance/expertise to team members on experiments/laboratory procedures.
• Coordinates/manages the work of junior team members.
• Leads and participates in general lab maintenance initiatives including but not limited to maintaining laboratory supplies and equipment, maintaining electronic inventory list database, physical inventory, processing/aliquoting/vialing/labeling materials, and preparing and maintaining reagent inventories.
• May be selected to monitor and report on the infrastructure of a particular lab or functional area.
• Specific duties may vary depending upon departmental requirements.
EXPERIENCE AND QUALIFICATIONS:
• Bachelor's degree in life sciences, or related area is required
o Master's degree is preferred
o Additional experience may be substituted for graduate degree
• A minimum of twelve years hands-on laboratory work experience is required.
KNOWLEDGE, SKILLS AND ABILITIES:
• Strong knowledge of scientific fundamentals with a protein biochemistry background.
• Strong knowledge of recombinant protein technology.
• Demonstrated aptitude for learning of and adhering to standard laboratory techniques and safety precautions.
• Working knowledge of protein chemistry, protein and/or peptide isolation and purification and conjugation methods.
• Desirable skills/tools may include but are not limited to:
o Vector design and construction for protein expression;
o Cell culture;
o Protein expression;
o Protein purification through column chromatography, including good working knowledge of FPLC and HPLC instruments;
o Analytical characterization of purified proteins by methods such as PAGE, Western, IEF, UV/Vis, etc.
• Ability to work both independently and as an effective team member.
• Ability to lead and guide other team members.
• Solid communication (written and verbal) skills regardless of the format (e.g., documents, public speaking situations, presentations, etc.).
• Excellent organizational, planning, and time management skills with the ability to manage multiple and often changing priorities and issues of varying complexity, while meeting time-sensitive deadlines and deliverables.
• Attention to detail with demonstrated commitment to excellence and performance.
• Demonstrated propensity to be creative, collaborative, proactive, and self-motivated in the execution and completion of assigned tasks.
• Ability to execute experiments, and to identify issues and propose/execute troubleshooting.
• Strong analytical skills with the demonstrated ability to gather and evaluate complex data and information and develop a recommendation and plan of action.
• Proficient in MS Excel.
PHYSICAL DEMANDS:
• While performing the duties of this job, the individual is frequently required to sit and stand for long periods. The individual is occasionally required to walk; use hands and fingers to operate, handle, or feel objects, tools, or controls; reach with hands and arms.
• Up to 75% of the day may be spent at a lab bench.
• There are aspects of the positions duties that require a person in this role to work at heights above four (4) feet on occasion and move/lift up to 25 pounds.
WORK ENVIRONMENT:
• Laboratory environment working with chemical reagents and performing some Biosafety Level 2 work
o May involve handling of BSL-2 materials and organisms including human blood and/or blood products.
COMPENSATION SUMMARY
The annual base salary for this position ranges from $88,100. to $134,400. This salary range represents a general guideline as MSD considers other factors when presenting an offer of employment, such as scope and responsibilities of the position, external market factors, and the candidate's knowledge, skills, abilities, education and experience. Employees may qualify for a discretionary or non-discretionary bonus in addition to their base salary. These annual bonuses are intended to recognize individual performance and enable employees to benefit from the Company's overall success.
BENEFITS SUMMARY
At MSD, we offer a comprehensive benefits package to support our employees' well-being and financial security. In addition to competitive salaries, our benefits include medical, dental, and vision coverage, along with prescription benefits. We provide a 401(k) plan with company matching, flexible spending accounts, and company-paid short- and long-term disability insurance as well as group life and accidental death and dismemberment insurance. Our offerings also encompass paid vacation, paid sick leave, paid holidays, and paid parental leave, along with an employee assistance program. Additional voluntary perks include a fitness club membership contribution, pet insurance, identity theft protection, home and auto insurance discounts, and optional supplemental life insurance.
