Sr. Technical Program Manager, AI Security

The Role:

Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. We’re looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.

Here’s What You’ll Do

• Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting

• Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process

• Build processes, templates, and structure, orleverageexisting ones as appropriate

• Manage vendors, schedule, scope, and cost

• Measure program success (or lack thereof) and risks using data and facts

• Provide balanced risk remediation strategies and recommendations and drive risk mitigation

• Develop andmaintainclose stakeholder relationships and build influence to drive theappropriate outcomesacross Moderna

• Provide clear,accurate, consistent, andtimelycommunications

• Advance good infrastructure and security practices and culture

• Partner Collaboration - work with Cybersecurity, Builder Tools & Platforms, Infrastructure, Identity & Endpoint Engineering, GRC, AI Engineering, Data, Enablement/L&D, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner

• Manage multiple initiativesto oversee the architecture and lifecycle of enterprise AI systems, including agent identity, tool authorization, and secure development practices; to drive governance frameworks that define permitted AI use, contextual standards, and regulatory alignment 6 including GxP where applicable; and to ensure end-to-end observability and monitoring of AI agents in production.

• Own the operating model for AI enablement programs, including pilots, cohorts, and phased rollouts, and partner with Enablement/L&D teams to shape rolebased learning paths for AI builders

• Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, andmaintainantiracist policies and processes

Here’s What You’ll Need (Minimum Qualifications)

• Experience: 8+ years in Technical Program Management, Engineering Program Management, or similar roles in AI/ML-heavy environments

• Technical Depth: Strong understanding of AI/ML systems, including model training pipelines, LLMs,MLOps, data pipelines, and cloud infrastructure

• Strong understanding of AI/ML development workflows, AIassisted engineering tools, or modern software development platforms

• Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills

• Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations

• Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion

• Experience improving developer productivity and building internal tools/platforms.

• Ability to define metrics, analyze tradeoffs, and drive decisions with data.

• Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback

• Proven ability tooperatein highly matrixed environments and influence without direct authority.

• Excellent written and verbal communication skills, including executivelevel storytelling

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Background in software engineering, data science, or machine learning

• Experience with LLM platforms, prompt engineering workflows, or AI copilots

• Experience with AI development platforms, copilots, developer tooling, orMLOpsconcepts

• Experience with responsible AI, model governance, or compliance frameworks

• Experience driving structured, process-driven AI transformation initiatives.

• Familiarity with tools such as Kubernetes, Airflow,MLFlow, or similarMLOpsstacks

• Familiarity with governed enablement models (e.g., citizen development, platform standards, golden paths)

• Knowledge of security and compliance standards relevant to AI and AI-assisted engineering.

• Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders

• Embrace a culture of continuous service improvement and service excellence

• A desire to make an impact as part of a high-growth, transformational company

• Experience with GxP environments and regulatory requirements