McKesson

Sr. Director, Infrastructure Operations

McKesson$151K — $201K *
Information Technology
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in IT, Computer Science, Business, or similar; advanced degree or certifications preferred.
  • 12+ years of experience in enterprise infrastructure operations with leadership roles.
  • Strong understanding of IT financial management, including budgeting and cost optimization.
  • Deep knowledge of enterprise infrastructure technologies with experience in compute, storage, backup, and cloud platforms.
  • Solid understanding of monitoring, patching, capacity management, and ITIL best practices.

Responsibilities

  • Own and manage day-to-day infrastructure operations for compute, storage, backup, and cloud services.
  • Ensure high availability and reliability for infrastructure platforms supporting critical business systems.
  • Define SLAs, SLOs, and KPIs, and implement proactive monitoring across all platforms.
  • Oversee performance and governance of Managed Service Providers (MSPs) to meet service quality standards.
  • Ensure compliance with cybersecurity policies and regulatory standards, leading vulnerability remediation efforts.
  • Manage operational budgets and drive cost optimization initiatives across all infrastructure services.
  • Build and lead a high-performing operations team while fostering a culture of accountability.

Benefits

  • Hybrid work environment.
  • Support for professional certifications and development.
  • Opportunities for leadership development and team building.
  • Emphasis on a culture of continuous improvement and accountability.
Full Job Description

Position Summary (Purpose of job):

The Senior Director,Enterprise Infrastructure Operationsis accountable for the stability, performance, security, and cost-effectiveness of all enterprise infrastructure services across on-premises and cloud environments. This role ensures operational excellence forcompute, storage, backup, and cloud-hosted workloads, while leading managed service providers (MSPs) and internal teams to deliver reliable, secure, and compliant services at scale.

This leader ownsInfrastructure Operations, ensuring services are resilient, measurable, and continuously improved to meet business and clinical needs.

Key Responsibilities:

1.Own End-to-End Infrastructure Operations:

  • Accountable for day-to-day operations ofcompute, storage, backup, and cloud infrastructure services.

  • Ensure high availability, performance, and reliability of all infrastructure platforms supporting business-critical systems.

  • Establish and enforce operational standards, procedures, and runbooks.

  • Lead incident, problem, and change management practices with a focus on minimizing business disruption.

2.Drive Operational Excellence & Service Reliability:

  • Define and manage SLAs, SLOs, and KPIs for infrastructure services.

  • Implement proactive monitoring, alerting, and capacity management across all platforms.

  • Lead root cause analysis andensurepermanent resolution of recurring issues.

  • Continuously improve operational maturity, automation, and service quality.

3.MSP &PartnerOperational Governance:

  • Own the performance and accountability of Managed Service Providers (MSPs).

  • Establish clear operating models, KPIs, and governance cadences with service providers.

  • Ensure adherence to SLAs, contractual obligations, and service quality expectations.

  • Partner with Vendor Management Office/ Sourcing &Procurementon renewals, performance management, and cost optimization.

4.Infrastructure Security, Risk & Compliance:

  • Ensure infrastructure operations comply with cybersecurity policies, audit requirements, and regulatory standards.

  • Lead remediation of vulnerabilities, patching compliance, and audit findings.

  • Partner with Security and Risk teams to strengthen operational resilience and reduce exposure.

  • Maintain audit readiness across all infrastructure domains.

5.Cloud & Hybrid Workload Operations:

  • Oversee operational management of workloads across hybrid and multi-cloud environments.

  • Ensure consistent operational practices across on-prem and cloud platforms.

  • Optimize cloud operations forperformance,and scalability.

  • Partner withCloud Platforms and InfrastructureEngineeringteamson transition to operations for newly deployed services.

6.Financial & Capacity Management:

  • Own infrastructure operational budgets, includingpartnersconsumption-based services.

  • Drive cost optimization initiatives acrosscompute, storage, backup, and cloud.

  • Provide transparency into cost drivers, forecasting, and allocation.

  • Align capacity planning with business demand and growth.

7.Documentation, Observability & Reporting:

  • Ensure accurate and up-to-date documentation of infrastructure services, configurations, and dependencies.

  • Deliver operational dashboards and executive reporting on performance, risks, and trends.

  • Provide actionable insights on capacity, utilization, and service health.

8.Leadership & Organizational Development:

  • Build and lead a high-performing operations organization, including internal teams and external partners.

  • Define clear roles and accountability between internal staff and MSPs.

  • Develop leadership capability within the team, particularly in operational discipline and service management.

  • Foster a culture of accountability, continuous improvement, and customer focus.

Minimum Requirements:

Education/Training

  • Bachelors degree in Information Technology, Computer Science, Business Administration, or related field; advanced degree or professional certifications in related areas preferred.

Critical Skills:

  • 12+ years of experience in enterprise infrastructure operations, including leadership roles overseeing large-scale, hybrid (on-prem and cloud) environments.

  • Strong understanding of IT financial management, including budgeting, forecasting,andcost optimization.

  • Broad knowledge of enterprise infrastructure technologies, with depth incompute, storage, backup, and cloud platforms, and the ability to govern complex environments.

  • Proven experience managing hybrid and cloud operations (preferably Microsoft Azure), including workload operations, cost control, and performance management.

  • Solid understanding of infrastructure operations disciplines: monitoring, patching, capacity management, incident/problem/change management.

  • Working knowledge of legacy platforms (e.g.IBMi(OS/400) / AS/400 environments) to ensure operational continuity and risk management.

  • Strong understanding of infrastructure security, risk, and compliance frameworks (e.g., SOX, SOC1&2), including audit readiness and vulnerability remediation.

  • Demonstrated experience in MSP/vendor management, including defining SLAs, driving performance, and holding partners accountable for outcomes.

  • Strong leadership skills with experience building and leading operations-focused teams, including managing internal staff and external providers.

  • Proven ability to drive operational excellence and service reliability in complex, large-scale environments.

  • Excellent stakeholder management and communication skills, with the ability to engage effectively at executive and operational levels.

  • Experience leading in highly complex, matrixed organizations, driving alignment across infrastructure, security, and application teams.

  • Strong knowledge of ITIL / IT Service Management practices (incident, problem, change, service level management).

  • Relevant certifications (cloud, ITIL, infrastructure technologies) are anasset;emphasis on operational leadership over technical specialization.

Working Conditions:

Environment (Office)

  • Traditional office environment.

  • Hybrid work type.

Physical Requirements (Lifting, standing, etc.)

  • Largepercentof time performingcomputer-basedwork is required.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please

Our Base Pay Range for this position

$151,200 - $201,600

About McKesson

McKesson Corporation provides medicines, pharmaceutical supplies, information and care management products and services across the healthcare industry. The Company operates in two segments. The McKesson Distribution Solutions segment delivers ethical drugs, medical-surgical supplies and equipment and health and beauty care products throughout North America. This segment also provides specialty pharmaceutical solutions for biotech and pharmaceutical manufacturers, sells financial, operational and clinical solutions for pharmacies (retail, hospital, long-term care) and provides consulting, outsourcing and other services. The McKesson Technology Solutions segment delivers enterprise-wide clinical, patient care, financial, supply chain, strategic management and software solutions. In July 2011, the Company acquired Portico Systems from Safeguard Scientifics, Inc. On March 25, 2012, it acquired the independent banner and franchise businesses of Katz Group Canada Inc. McKesson Distribution Solutions delivers pharmaceuticals to retail pharmacies and institutional providers like hospitals and health systems. They operate pharmaceutical distribution centers across the country, serving customers in all 50 states. They also deliver a comprehensive offering of health care products, technology, equipment and related services to the alternate site market, including physician offices, surgery centers, long-term care facilities and home care businesses across the country. McKesson is currently the largest pharmaceutical distributor in North America. McKesson also operates McKesson Canada and has an equity holding in Nadro, a leading distributor in Mexico.

McKesson Careers

Join McKesson, a leading global healthcare company, and be part of a team that is redefining the future of healthcare. With a variety of job opportunities available, McKesson is the perfect place to advance your career, whether you're a seasoned professional or just starting out. Work You’ll Do At McKesson, we are committed to improving care in every setting—one product, one partner, one patient at a time. We’re seeking talented professionals to join our team and contribute to a culture of innovation, diversity, and leadership. Our employees are driven by a deep sense of purpose and a desire for continuous growth and improvement. Empower Your Future in Healthcare With positions ranging from internships to leadership roles, McKesson offers unparalleled employment opportunities to develop your skills and advance your career. Our commitment to diversity training ensures that all team members have the opportunity to thrive. Join a team where your skills will be honed, your professional growth will be supported, and where you can genuinely see the difference you make in the lives of patients around the world. Innovative Work Environment McKesson is at the forefront of healthcare innovation. Our team is constantly exploring new ways to improve patient outcomes and streamline care processes. This commitment to innovation is what sets us apart and what makes McKesson an exciting place to work. Career Development and Benefits McKesson believes in nurturing the potential of its employees through robust career development programs and comprehensive benefits designed to support your life and well-being. From leadership training to health and wellness benefits, we ensure our team members are equipped to meet their professional and personal goals. Explore Job Opportunities Whether you’re looking for an internship to kickstart your career, or a senior position to utilize your extensive experience, McKesson offers a range of opportunities. Explore our open positions and find where you can make a difference at McKesson. Stay Connected Join Our Team Search for open positions that match your skills and interests. We are looking for passionate, curious, and solution-driven team players who are ready to take the next step in their careers. Keep Up to Date Stay ahead with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Networking and Professional Growth At McKesson, networking and professional growth are part of our everyday environment. We encourage our employees to connect, share, and learn from each other to foster personal and professional development. Job Alert Emails Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await you at McKesson. Join McKesson today and be part of a team that is dedicated to shaping the future of healthcare.
Learn more about McKesson
Size
58,000 employees
Market Cap
$53.7 billion
Industry
Net Income
-$4.1 billion
Founded
1833
5 Year Trend
+5.9%
Revenue
$237.6 billion
NASDAQ

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