Tango Therapeutics

Senior Vice President, Market Access

Tango Therapeutics$337K — $500K+*
Pharmaceuticals & Biotech
15+ years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree required; advanced degree (MBA, PharmD, MPH, or related discipline) preferred.
  • 20+ years of biopharmaceutical experience, particularly in market access and pricing.
  • Proven executive experience through critical corporate transitions (clinical to commercial).
  • Track record of successful U.S. market access launches for oral oncology or rare disease therapies.
  • Strong financial acumen with expertise in gross-to-net strategies and contract management.

Responsibilities

  • Architect and scale a fully integrated market access organization for oncology product launches.
  • Lead and mentor a high-performing leadership team across key market access functions.
  • Serve as the strategic anchor for market access at the C-suite level.
  • Champion the enterprise-wide value proposition through Health Economics and Outcomes Research (HEOR).
  • Oversee global access strategies, ensuring alignment across U.S. and Ex-U.S. markets.
  • Develop pricing and contracting strategies to optimize product value across commercial segments.
  • Design a distribution network that balances control with community access for specialty therapies.

Benefits

  • Hybrid work model with flexibility.
  • Opportunities for leadership development and executive mentorship.
  • Access to a collaborative and innovative work environment.
  • Support for work-life balance initiatives.
Full Job Description
Summary

The Senior Vice President (SVP) of Market Access is a critical enterprise leader responsible for architecting and executing the overarching market access, patient services, pricing, and distribution vision for Tango Therapeutics. As the company transitions from a research-stage biotech into a fully integrated commercial organization, this executive will define the access roadmap for our pipeline of precision synthetic lethality oral medicines.

Reporting directly to the Chief Commercialization Officer and serving as a key pillar of the Commercial Leadership Team, the SVP will build a world-class market access infrastructure from the ground up. This leader will ensure that the clinical promise of our assets is met with frictionless patient access, optimized commercial value, and sustainable market positioning on a global scale.

Your Role:

Enterprise leadership & Organizational Design
  • Architect the Access Function: Design, build, and scale a best-in-class, fully integrated market access organization capable of supporting multiple oral oncology product launches
  • Executive Mentorship: Lead, empower, and mentor a high-performing leadership team encompassing critical functions across global value and access, health economics and outcomes research (HEOR), strategic operations, patient services, trade operations, and payer strategy
  • Cross-Functional Vision: Serve as the strategic anchor for market access within the C-suite and across the enterprise, ensuring that value demonstration, pricing elasticity, and payer insights are embedded into early-stage asset development and overarching commercial strategy

Strategic Priorities:

Global Value & Health Economics
  • Value Proposition Strategy: Champion the enterprise-wide value proposition, directing the strategic generation of Health Economics and Outcomes Research (HEOR) to support compelling, evidence-based narratives for health technology assessments and global payers
  • Global Access Alignment: Oversee the integration of U.S. and Ex-U.S. access strategies, ensuring a cohesive global approach to value demonstration and market entry

Pricing, Payer Strategy & Policy
  • Innovative Pricing Paradigms: Formulate sophisticated launch pricing, gross-to-net (GTN) strategies, and contracting frameworks that maximize product value and ensure favorable positioning across Commercial, Medicare Part D, and Medicaid segments
  • Policy Anticipation & Advocacy: Act as the organization's foremost authority on the evolving healthcare policy landscape (e.g., Medicare Part D redesigns, PBM legislation), proactively steering corporate strategy to mitigate risks and capitalize on market shifts
  • Government Pricing Optimization: Deep understanding of government programs and calculations. Proven ability to forecast the structural impacts of federal pricing programs, ensuring access strategies align with long-term portfolio revenue goals

Channel Architecture & Patient Experience
  • Strategic Distribution Network: Architect an optimal, scalable specialty pharmacy (SP) and distribution network tailored exclusively for high-value oral oncology therapeutics, balancing network control with broad community oncology access
  • Best-in-Class Patient Support: Define the vision for Tango's Patient Services and hub infrastructure, driving strategies that eliminate access friction, optimize time-to-therapy, and deliver superior patient experience


What You Bring:

Education & Experience
  • Bachelor's degree required; advanced degree (MBA, PharmD, MPH, or related discipline) strongly preferred
  • 20+ years of progressive biopharmaceutical experience, with a significant tenure in executive-level market access, pricing, and commercial strategy roles
  • Demonstrated enterprise leadership experience, successfully transitioning companies through critical inflection points (e.g., clinical-stage to commercial-stage)
  • A proven track record of architecting and leading successful U.S. market access launches for novel oral oncology or rare disease therapies

Core Competencies
  • Strategic Acumen: Deep understanding of complex oral oncology treatment paradigms, pharmacy benefit designs, and the financial mechanics of specialty distribution and PBM negotiations
  • Visionary Leadership: Exceptional ability to recruit, develop, and inspire a diverse team of senior functional leaders
  • Executive Presence: Highly developed communication and negotiation skills, with the ability to influence corporate boards, C-level peers, and top-tier external payer and channel partners
  • Financial & Analytical Mastery: Advanced capability in modeling complex gross-to-net scenarios, managing high-stakes contract strategies, and aligning access operations with overarching corporate financial goals


#LI-Hybrid

Salary range

$337,600-$506,400 USD

About Tango Therapeutics

Tango Therapeutics is a biotechnology company that develops targeted cancer therapies. The company's approach is based on a deep understanding of the genetic drivers of cancer, and it uses this knowledge to develop drugs that can selectively target cancer cells. Tango Therapeutics was founded in 2017 and is headquartered in Cambridge, Massachusetts. The company has partnerships with a number of other biotech and pharmaceutical companies, and it has received funding from a variety of sources, including venture capital firms and government agencies.
Learn more about Tango Therapeutics
Size
51 employees
Market Cap
$617.3 million
Industry
Founded
2017
NASDAQ

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