Senior Software Engineer (5+ years)

Foresite Labs • $185K — $221K *

San Francisco, CA 94112In-Person

Information Technology

5 - 7 years of experience

More than 3 months ago

Job Overview by Ladders

Qualifications

5+ years in software engineering with experience in greenfield projects
Proficiency in TypeScript and at least one backend language (Python, Go, Java)
Familiarity with key AWS (or GCP/Azure) services and infrastructure as code tools
Experience with Unix environments, Docker, and CI/CD tools
Hands-on knowledge of LLM systems and frameworks like LangChain
Ability to navigate ambiguous situations with a proactive mindset
Strong communication skills for technical and non-technical audiences

Responsibilities

Design and build production software systems and services from scratch
Deliver end-to-end features across frontend and backend technologies
Create intuitive user interfaces for complex workflows
Utilize AI-native development tools to streamline coding processes
Conduct code and design reviews, while mentoring peers
Collaborate with interdisciplinary teams to translate goals into technical solutions

Benefits

Opportunity to impact therapeutic discoveries and AI-driven innovation
Autonomy in architecting and owning solutions in a streamlined environment
Learning opportunities at the intersection of software, cloud, and biology
Comprehensive healthcare, competitive salary, and flexible PTO
Hybrid/remote work options available from SF or Boston

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Full Job Description

What You'll Do

Build from scratch. Design, implement, and own production-grade software systems, services, data pipelines, internal tools, often starting from scratch and evolving them through MVP, scale-up, and sustained operation.
Ship features end-to-end. Work across the stack, with meaningful ownership of frontend applications built in React and Tailwind CSS as well as backend services and APIs, to deliver product value quickly and iterate with feedback.
Create polished user experiences. Translate ambiguous user and business needs into intuitive, performant interfaces that make complex scientific and operational workflows easier to use.
Use modern AI-native development workflows and agentic coding tools, such as Claude Code or Codex, to accelerate prototyping, implementation, refactoring, and debugging
Uphold high engineering standards. Lead code and design reviews, establish testing and monitoring best practices, and collaborate with and mentor peers in clean, maintainable software.
Collaborate broadly. Pair with machine learning engineers and scientists, computational biologists, and portfolio company founders to translate scientific or business goals into robust technical solutions.

What You'll Bring

5+ years of professional software engineering experience, including shipping greenfield systems you personally bootstrapped and supported in production.
Fluency in TypeScript and at least one modern backend language (Python, Go, Java, etc.), with strong experience building production full-stack applications.
Working knowledge of AWS (or GCP/Azure) core services and patterns-VPC, IAM, ECS/EKS/Lambda, RDS, S3-and experience expressing infrastructure as code with Terraform, CDK, or Pulumi a plus.
Comfort navigating Unix environments, containers (Docker), and CI/CD pipelines (GitHub Actions, GitLab, or similar).
Hands-on experience with LLM systems and agentic application frameworks, including familiarity with tools such as LangChain and Pydantic AI, and an understanding of how to build production-oriented workflows involving tool use, structured data, multi-step reasoning, iterative loops, testing, and orchestration.
Mindset for early-stage execution: bias for action, ownership of ambiguous problem spaces, and ability to wear multiple hats without extensive support structures.
Excellent written and verbal communication skills; you explain complex ideas clearly to technical and non-technical partners.

Why Foresite Labs

Impact. Your code will accelerate discovery and bring novel therapeutics closer to patients and will help AI driven scientific innovation.
Autonomy. Small, senior teams give you room to architect and own end-to-end solutions without heavy bureaucracy.
Learning. Work at the intersection of software, cloud infrastructure, and biology alongside experts in each domain.
Flexibility & Benefits. Competitive salary and equity, comprehensive healthcare, generous PTO, and hybrid/remote options aligned to our SF or Boston hubs.
Ready to build? Apply today and help us create the software foundation that powers the next generation of companies advancing biotech and scientific innovation.

Location: San Francisco, CA

Salary range: $185,000 - $221,400

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About Foresite Labs

Foresite Labs is a venture capital firm that invests in early-stage healthcare and life sciences companies. The firm was founded in 2019 by Jim Tananbaum, a healthcare entrepreneur and investor. Foresite Labs is a subsidiary of Foresite Capital, a leading healthcare investment firm. The firm's portfolio includes companies in the areas of biotechnology, medical devices, digital health, and healthcare services. Foresite Labs provides funding, strategic guidance, and operational support to its portfolio companies. The firm is based in San Francisco, California.

Learn more about Foresite Labs

Size

1 employees

Industry

Pharmaceuticals & Biotech

Founded

2019

* Ladders Estimates

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