Advanced degree in Cell Biology, Molecular Biology, Bioengineering, Biotechnology, or related discipline (MS preferred)
Extensive R&D experience in cell culture, cell line development, or bioprocess engineering
Industry experience in biologics, cell therapy, or related manufacturing environments
Strong aseptic technique and sterile handling skills
Solid understanding of mammalian cell culture fundamentals
Familiarity with laboratory safety and biosafety practices
Basic knowledge of bioreactor operations and microscopy
Responsibilities
Retrieve, thaw, and initiate mammalian cell lines from cryogenic storage
Monitor culture health, morphology, viability, and contamination status
Expand cultures through multiple vessel scales to generate inoculum
Install and prepare single-use cultureware systems for bioreactor setup
Perform system pressurization testing and leak checks
Harvest cultures for long-term storage and prepare freezing suspensions
Maintain accurate batch records and laboratory documentation
Benefits
Collaborative work environment with cross-functional teams
Opportunity to drive process excellence and optimize production performance
Engagement in cutting-edge research and development
Focus on quality and operational excellence in production
Support for ongoing professional development and training
Full Job Description
Overview
is seeking an accomplished scientific leader to oversee antibody and resin production in support of the VICAM® column production value stream. In this critical role, you will collaborate closely with Research & Development, Engineering, and Manufacturing teams to ensure the reliable, on-time production of antibodies and resins that meet quality, capacity, and operational requirements. The successful candidate will drive process excellence, optimize production performance, and ensure a consistent supply of key materials to support customer demand and the ongoing success of the column production line.
Responsibilities
Cell Culture Operations
Retrieve, thaw, and initiate mammalian cell lines from cryogenic storage
Monitor culture health, morphology, viability, and contamination status
Perform routine passaging and expansion of cell cultures
Maintain safety-stock cultures and frozen cell banks
Perform sterile manipulations within biosafety cabinets
Seed Train Expansion
Expand cultures through multiple vessel scales to generate inoculum
Evaluate expansion readiness based on growth phase and culture condition
Perform aseptic transfers, media additions, and feeding activities
Maintain proper labeling and tracking of cultures
Bioreactor Setup & Operation
Install and prepare single-use cultureware systems
Perform system pressurization testing and leak checks
Execute fill, flush, and priming procedures
Perform bioreactor inoculation activities
Monitor process parameters including temperature, pH, dissolved oxygen, and gas supply
Collect in-process samples for routine analysis
Cryopreservation & Cell Banking
Harvest cultures for long-term storage
Prepare freezing suspensions using appropriate cryoprotectants
Aliquot into cryovials and perform controlled freezing steps
Maintain cryogenic storage inventory and records
Documentation & Compliance
Maintain accurate batch records and laboratory documentation
Record culture observations, process steps, and test results
Follow established SOPs and aseptic handling procedures
Adhere to safety and biosafety requirements
Qualifications
Education & Qualifications
Advanced degree in a relevant field - Bachelor Degree in Cell Biology, Molecular Biology, Bioengineering, Biotechnology, or related discipline required, MS preferred.
Extensive research and development experience in cell culture, cell line development, or bioprocess engineering.
Industry experience in biologics, cell therapy, or related manufacturing environments.
Waters Corporation is a publicly traded Analytical Laboratory instrument and software company headquartered in Milford, Massachusetts. The company designs, manufactures, sells and services high performance liquid chromatography, ultra performance liquid chromatography, and mass spectrometry technology systems and support products primarily in the United States, Europe, Japan, and Asia. The company's products are used by pharmaceutical, life science, biochemical, industrial, academic and government organizations working in research and development, quality assurance and other laboratory applications. Waters Corporation's products are sold worldwide through a direct sales force and independent distributors.
