Job Type
Full-time
Description
The Senior Scientist, Bioproduction & Bioprocessing is responsible for leading the development, optimization, and execution of mammalian cell-based protein production workflows to support organizational research, development, and manufacturing needs. This role provides subject-matter expertise in cell line development, transient expression, and upstream bioprocessing, and ensures high-quality delivery of materials through collaboration with cross-functional teams. The Senior Scientist contributes to scientific innovation, process improvement, and customer support activities.
- Lead and execute workflows for stable pool and stable cell line generation, including transfection, clone screening, productivity assessment, and documentation.
- Perform stable pool and transient experiments using CHOZN, CHOK1-sv, CHOK, HEK293, and other protein production-relevant cell lines.
- Develop, optimize, and scale transient protein expression processes for antibodies and recombinant proteins.
- Conduct upstream protein expression studies, including small-scale evaluations and preparation for scale-up.
- Design, perform, and troubleshoot laboratory experiments in accordance with established protocols, quality standards, and regulatory expectations.
- Analyze experimental data, prepare technical summaries, and present results to internal and external stakeholders.
- Collaborate with downstream purification, analytical development, and project management teams to ensure alignment and timely delivery of materials.
- Provide scientific support to customer-facing teams, including remote and onsite troubleshooting with Field Application Scientists.
- Identify opportunities to enhance bioproduction workflows, including media/feed optimization, vector improvements, and process parameter refinement.
- Evaluate and implement new technologies, automation tools, and high-throughput approaches to increase efficiency and scalability.
- Lead exploratory studies to assess emerging bioprocessing methods and integrate validated improvements into standard workflows.
- Contribute to internal innovation initiatives, including development of new production strategies, platform enhancements, and scientific capability expansion.
- Provide technical insight to support long-term bioproduction strategy and organizational growth.
- Maintain accurate, complete, and compliant laboratory records.
- Ensure adherence to organizational, regulatory, and safety standards.
Requirements
- PhD in biological sciences or related field with 10+ years of relevant industry experience (or Master's degree with 13+ years of experience) in bioproduction, bioprocessing, or cell line development
- Demonstrated expertise in stable cell line development and clone selection.
- Extensive hands-on experience with transient expression of antibodies or recombinant proteins.
- Strong foundation in mammalian cell culture and upstream protein expression.
- Experience with high-throughput screening, automation, or advanced analytical tools.
- Background in cell engineering, vector design, media/feed optimization, or bioprocess development.
- Prior experience in structured, milestone-driven industry or core laboratory environments.
- Good communication skills and ability to work collaboratively with internal team members and customers
- Ability to travel up to 20%
MaxCyte offers a base salary, annual bonus, and equity. MaxCyte also offers a comprehensive benefits package including health, dental, vision, life, and disability insurance and generous time off.
