Revolution Medicines

Senior Research Associate, DMPK

Revolution Medicines • $106K — $126K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's or master's degree in pharmaceutical sciences or related field; 5+ years experience (bachelor's) or 3+ years (master's).
  • Hands-on experience with LC-MS/MS operation and maintenance.
  • Experience in LC-MS/MS method development and bioanalytical analysis.
  • Familiarity with biological sample preparation and extraction for LC-MS/MS.
  • Proficiency in HPLC/UPLC method development.
  • Strong organizational skills and ability to manage multiple tasks.

Responsibilities

  • Develop LC-MS/MS methods and analyze biological samples for studies.
  • Prepare various tissues for bioanalysis, including tumors.
  • Conduct data analysis and prepare experimental reports.
  • Perform in vitro ADME/DMPK assays using various biological matrices.
  • Support lab operations, ensuring safety and maintaining LC-MS/MS equipment.

Benefits

  • Competitive cash compensation.
  • Robust equity awards.
  • Strong benefits package.
  • Significant learning and development opportunities.
Full Job Description
The Opportunity:

As a key member of our dynamic DMPK lab team within DMPK under the non-clinical development and clinical pharmacology (NDCP) department, you will have responsibilities including, but not limited to:
  • Develop LC-MS/MS methods and analyze in vivo and in vitro samples to support ADME, pharmacokinetic, efficacy, and toxicokinetic studies, etc.
  • Handle a variety of tissues, including tumors, from tissue homogenization through sample preparation for bioanalysis.
  • Perform data analysis, prepare experimental result reports, and upload data to electronic notebooks.
  • Conduct in vitro ADME/DMPK assays in biological matrices, including hepatocytes, microsomes, blood, and plasma, ect.
  • Support laboratory operations, including lab safety, LC-MS/MS instrument maintenance and troubleshooting.

Required Skills, Experience and Education:
  • Bachelor's or master's degree in pharmaceutical sciences or a related scientific discipline, with 5+ years of industry experience for bachelor's degree holders or 3+ years for master's degree holders.
  • Hands-on experience in operating and maintaining LC-MS/MS systems.
  • Hands-on experience in LC-MS/MS method development and bioanalytical analysis.
  • Knowledge of biological sample preparation and extraction techniques for downstream LC-MS/MS analysis.
  • Hands-on experience in HPLC/UPLC method development.
  • Ability to customize and follow established assay protocols.
  • Ability to manage multiple laboratory and project tasks efficiently.
  • Ability to work effectively in a flexible, team-oriented environment.
  • Highly organized and detail-oriented, with excellent recordkeeping skills and the ability to adapt to a dynamic, fast-paced environment.

Preferred Skills:
  • Previous hands-on experience in SCIEX QTRAP mass spectrometers.
  • Previous hands-on experiences on bioanalytical method development in compliance with regulatory requirements.
  • Working experience in DMPK lab.

#LI-CT1 #LI-ONSITE

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Base Pay Salary Range

$106,000-$126,000 USD

We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.

Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.

If you believe you've been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.

About Revolution Medicines

Revolution Medicines is a clinical-stage precision oncology company focused on developing targeted therapies to inhibit elusive frontier targets within notorious growth and survival pathways, with particular emphasis on RAS and mTOR signaling pathways. The company's proprietary platform enables the discovery and development of small molecules that bind covalently to proteins. Revolution Medicines was founded in 2014 and is headquartered in South San Francisco, California.
Learn more about Revolution Medicines
Size
201 employees
Market Cap
$2.1 billion
Industry
Net Income
-$108.1 million
Revenue
$42.9 million
NASDAQ

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