BristolMyers Squibb

Senior Principal Scientist, Cancer Immunology, Discovery Biology, Oncology Thematic Research Center

BristolMyers Squibb$174K — $210K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. or equivalent advanced degree in Life Sciences with at least 6 years of industry experience or a Bachelor's/Master's with equivalent leadership experience.
  • 8+ years of academic and/or industry experience if holding a Master's degree.
  • 10+ years of relevant experience if holding a Bachelor's degree.
  • 2+ years of leadership experience in related fields.
  • Experience developing novel immune therapeutic approaches, specifically involving T cell redirected therapies.

Responsibilities

  • Lead multidisciplinary teams in T cell engager and cancer immunology discovery from concept to IND.
  • Mentor junior scientists while overseeing in vitro experimentation.
  • Deploy advanced techniques for identifying and selecting drug candidates.
  • Collaborate with different functional area leads to define program priorities and mitigate risks.
  • Interfacing with external partners to advance research assets.
  • Present scientific concepts to diverse audiences, including governance meetings.
  • Utilize strong communication skills for effective collaboration.

Benefits

  • Comprehensive health coverage including medical, pharmacy, dental, and vision care.
  • Well-being support programs and an Employee Assistance Program (EAP).
  • Financial well-being protections such as 401(k), life insurance, and identity theft benefits.
  • Unlimited flexible paid time off for U.S. Exempt Employees with manager approval.
  • Additional paid volunteer days and flexible summer hours depending on eligibility.
Full Job Description

Position Summary:

We are seeking an innovative immunologist and leader to help shape our strategy and advance our portfolio of pioneering T cell engager and cancer immunology therapies to treat cancers. As a successful candidate you will be part of a multi-disciplinary, groundbreaking team within Discovery Biology at the Oncology Thematic Research Center in Seattle, WA, driving projects from concept to clinic, leveraging proprietary technologies and collaborating with top experts in the field.  You will work with leadership to define strategy, provide mentorship to junior scientists, and drive multi-functional teams to bring both internal and external assets to patients.  Our team thrives on creativity, rigorous science, and a shared commitment to transforming cancer care.

Position Responsibilities:

In the role as a Senior Principal Scientist within Discovery Biology, the ideal candidate will:

  • Lead matrixed TCE / cancer immunology discovery teams from target concept to IND and lead/mentor a biology team supporting in vitro experimentation. 

  • Deploy existing and new techniques for function-based identification and selection of lead drug candidates

  • Leverage experience and insights to shape overall strategy and inform the next wave of therapeutic innovation.

  • Collaborate with functional area leads e.g. pharmacology, DMPK, bioinformatics to drive programs forward, including helping to define program priorities and risks.

  • Collaborate with multi-disciplinary teams from external partners to help drive assets forward.

  • Present complex concepts to a range of audiences including governance and full team project meetings.

  • Utilize excellent communication and interpersonal skills.

  • Communicate via email, meetings, and reports.

Experience =

Basic Qualifications:

  • Bachelor’s Degree

    • 10+ years of academic and / or industry experience

Or

  • Master’s Degree

    • 8+ years of academic and / or industry experience

Or

  • Ph.D. or equivalent advanced degree in the Life Sciences  

    • 6+ years of academic and / or industry experience

  • 2+ years of leadership experience

Preferred Qualifications

  • Ph.D. or equivalent advanced degree in the Life Sciences  

    • 6+ years of industry experience

    • 2+ years of leadership experience

  • Experience developing novel immune therapeutic approaches for cancer including T cell redirected therapies.

  • Experience leading teams charged with profiling and developing complex biologics to drive enhanced immune function in the tumor microenvironment, with a strong preference for experience in discovery of T cell engagers. 

  • Experience in both high throughput screening, and biologically complex, cell based assays to drive mechanistic insight and prioritization of therapeutic leads.  Experience in interpreting in vivo functional assays. 

  • Experience leading and collaborating across matrixed discovery programs from concept to IND including with immune cell engagers. 

  • Experience contributing to an IND.

  • Strong leadership, interpersonal, and communication skills.

  • Ability to efficiently manage and prioritize multiple projects, coordinating in-house research with collaborative work.

  • Ability to summarize and interpret complex scientific data in a clear, concise, and accurate manner.

  • Experience leading, coaching and mentoring a team of lab-based in vitro biologists.

  • Excellent oral and written communication skills. 

  • Ability to communicate well with peers, supervisors, and governance committees.

  • Strong problem-solving skills and understanding of complex scientific principles and demonstrated experience leveraging AI to refine strategic and tactical planning.

#LI-Onsite

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

Seattle - WA: $174,020 - $210,872

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. 

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.
 

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

  • Health Coverage: Medical, pharmacy, dental, and vision care.

  • Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

  • Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

​Work-life benefits include:

Paid Time Off

  • US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

  • Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

About BristolMyers Squibb

BristolMyers Squibb Careers

Join the vibrant team at BristolMyers Squibb, a leader in global biopharmaceutical innovation, where your career growth is as important as the life-changing solutions we develop. At BristolMyers Squibb, we are committed to fostering a diverse and inclusive workplace that encourages professional growth and development. Work You’ll Do Embark on a career with BristolMyers Squibb and be part of a company that’s dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. With us, you’ll contribute to a culture that embraces scientific innovation, responsible leadership, and community outreach. Explore job opportunities in various fields from research to marketing, and join a team that values leadership and diversity. Our commitment to career growth means we support your journey with extensive training programs, leadership development opportunities, and a global, diverse network of professionals. Innovative Work At BristolMyers Squibb, innovation is at the core of everything we do. From pioneering research in oncology to breakthroughs in immunology, our professionals have the opportunity to make significant contributions to the field and impact lives globally. Our collaborative environment encourages team members to challenge the status quo and bring forward ideas that pave the way for groundbreaking solutions. Be Part of a Great Team Working at BristolMyers Squibb means being part of a team that supports your aspirations and shares your values. Our culture thrives on teamwork, respect, and diversity, creating a workplace where everyone can achieve their potential. Enjoy the benefits of being part of a company that values work-life balance, provides competitive benefits, and fosters an environment where skills and leadership are developed through hands-on experience and comprehensive mentorship programs. Future-Proof Your Career With a multitude of job opportunities ranging from internships to full-time positions, BristolMyers Squibb is not just hiring; we’re building futures. We equip our employees with the tools needed for success, including advanced training in diverse skill sets, leadership programs, and opportunities for professional networking and growth. Stay Connected Join Our Team Search open positions that match your skills and interests. We are looking for passionate, curious, and innovative team players who are ready to make a difference. Explore our career portal for all current job listings and be sure to submit your resume. Keep Up to Date Stay informed with the latest company news, career tips, and industry insights from BristolMyers Squibb. Our careers blog is a resource for potential and current employees looking to maximize their career potential. Job Alert Emails Customize your subscription to receive job alerts and insider information tailored to your preferences. Discover the exciting and rewarding career opportunities that await at BristolMyers Squibb. At BristolMyers Squibb, your career is just the beginning – it’s a pathway to personal and professional fulfillment. Join us and make a global impact.
Learn more about BristolMyers Squibb
Size
32,200 employees
Market Cap
$156.3 billion
Industry
Net Income
-$9 billion
Founded
1887
5 Year Trend
+19%
Revenue
$42.5 billion
NASDAQ

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