Pennsylvania Medicine

Senior Principal Enterprise Architect

Pennsylvania Medicine$130K — $180K *
Healthcare
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's Degree in Computer Science, Computer Engineering, Information Systems, or related field.
  • 15+ years of IT experience, including 10+ years in Enterprise Architecture in healthcare or regulated environments required.
  • 5+ years in EA roles with experience in developing operating models and governance frameworks at enterprise scale.
  • TOGAF Certification preferred for enterprise architecture proficiency.
  • Demonstrated leadership in cross-domain architecture within clinical, research, academic, and operational contexts.

Responsibilities

  • Develop and maintain the enterprise architecture operating model and governance frameworks.
  • Create multi-year enterprise architecture blueprints aligned with the strategic plan.
  • Translate business strategies into actionable architectural directions.
  • Define and enforce the EA taxonomy and artifact standards for consistency.
  • Co-lead the Architecture Review Board and its governance charters and decision frameworks.
  • Lead assessment and selection of enterprise EA repository and tools.
  • Drive the enterprise AI architecture strategy and responsible governance frameworks.

Benefits

  • Comprehensive compensation and benefits program.
  • Exceptional prepaid tuition assistance program.
  • Focus on employee health and wellness initiatives.
  • Opportunities for engagement and commitment to a vital mission.
Full Job Description
Entity: Corporate Services Department: Enterprise Technology Architecture and Strategy Location: Hybrid, 3535 Market St, Philadelphia, PA 19104 Summary:
  • Senior Principal Enterprise Architect - Enterprise Strategy & Transformation serves as a foundational enterprise architecture leader responsible for establishing, scaling, and maturing the Enterprise Architecture (EA) function across Penn Medicine's clinical, research, academic, and administrative domains. This senior individual contributor role operates at leadership level, providing enterprise-wide architectural leadership, governance, and strategic direction to DTS, clinical, research, academy, and operational leadership. The role is cross-domain, designed to engage any strategic initiative assigned to the EA portfolio by the Vice President. The incumbent is accountable for developing multi-year enterprise architecture blueprints, defining and evolving the EA operating model and governance frameworks, co-leading the Architecture Review Board, and advancing enterprise AI strategy. This role also leads the assessment and selection of the enterprise EA repository and tooling, and mentors Principal, Domain, and Solution Architects across the organization. The role does not own delivery, operations, or engineering execution. It provides architectural direction, governance, and enterprise coherence, and must flex to support any priority initiative assigned by the Vice President, Enterprise Architecture, Research & Strategy.
Responsibilities:
  • Develops and maintains the enterprise architecture operating model, including governance frameworks, standards libraries, decision rights, roles and responsibilities, and engagement models that enable consistent, enterprise-wide architectural coherence.
  • Develops multi-year enterprise architecture blueprints aligned to Penn Medicine's strategic plan, encompassing clinical, research, academic, and administrative technology domains, and presenting findings and recommendations to C-suite and executive leadership.
  • Translates enterprise and business strategy into actionable architecture direction, working with executive and operational leadership to define the Business Capability Model, identify capability gaps, and align technology investments to strategic priorities across Penn Medicine's integrated missions.
  • Defines, evolves, and enforces the enterprise architecture taxonomy, metamodel, and artifact standards, ensuring consistency and usability of EA artifacts across domains and stakeholder audiences.
  • Co-leads the Architecture Review Board (ARB), establishing ARB charter, review criteria, escalation pathways, and decision frameworks that govern architectural decisions across the enterprise portfolio.
  • Leads the assessment, requirements definition, vendor evaluation, and selection of the enterprise EA repository and tooling platform, including defining the taxonomy, metamodel, and usage standards for EA artifact management.
  • Defines and drives the enterprise AI and generative AI architectural strategy, including reference architectures for embedded AI, large language models (LLMs), retrieval-augmented generation (RAG), and responsible AI governance frameworks.
  • Develops and maintains the Business Capability Model, enterprise application portfolio inventory, and technology investment rationalization frameworks that inform strategic planning and capital prioritization decisions.
  • Governs enterprise technical debt identification, prioritization, and remediation roadmaps, partnering with delivery and operations leaders to ensure systematic reduction of architectural risk across the technology portfolio.
  • Mentors and upskills Principal, Domain, and Solution Architects across the organization, advancing architectural thinking, standards adoption, and governance participation at all levels of the architecture practice.
  • Partners with the DTS leadership, and clinical, operational, and research leadership to advise on strategic architecture decisions, technology investment trade-offs, and long-range platform direction.
  • Produces executive architecture briefings, strategy documents, and board-level presentations that communicate enterprise architecture direction, portfolio health, and strategic technology recommendations in terms accessible to non-technical leadership.
  • Flexes to lead or support any strategic initiative, program, or architecture assessment assigned to the EA backlog by the Vice President, Enterprise Architecture, Research & Strategy, providing domain-agnostic architectural leadership as organizational priorities evolve.
  • Monitor current and emerging technology trends across the healthcare, research and enterprise technology landscape. Evaluates strategic and architectural implications and communicates findings to executive leadership to inform long term technology investment decision.
  • Leads technology scenario planning to anticipate future business, regulatory, and technology changes; incorporates flexibility and resilience into enterprise architecture roadmaps to reduce lock in and improve adaptability.
  • Performs duties in accordance with Penn Medicine and entity values, policies, and procedures.
  • Other duties as assigned to support the unit, department, entity, and health system organization.
Credentials:
  • Enterprise Architecture TOGAF Certification is preferred.
Education or Equivalent Experience:
  • Bachelor's Degree is required. Education Specialization: Computer Science, Computer Engineering, Information Systems, or related field.
  • 15+ years of experience in Information Technology, Computer Science, Information Systems, or a related field, with 10+ years in Enterprise Architecture and demonstrated experience in enterprise-scale healthcare, academic medical center, or highly regulated industry environments is required.
  • 5+ years Enterprise Architecture experience, with demonstrated delivery of EA operating models, governance frameworks, ARB leadership, and multi-year architecture blueprints at enterprise scale is required.
We believe that the best care for our patients starts with the best care for our employees. Our employee benefits programs help our employees get healthy and stay healthy. We offer a comprehensive compensation and benefits program that includes one of the finest prepaid tuition assistance programs in the region. Penn Medicine employees are actively engaged and committed to our mission. Together we will continue to make medical advances that help people live longer, healthier lives. Live Your Life's Work

About Pennsylvania Medicine

The University of Pennsylvania is a private Ivy League research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest-regarded universities by numerous organizations and scholars. While the university dates its founding to 1740, it was created by Benjamin Franklin and leading Philadelphia citizens in 1749 . The University has four undergraduate schools as well as twelve graduate and professional schools. Schools enrolling undergraduates include the College of Arts and Sciences, the School of Engineering and Applied Science, the Wharton School, and the School of Nursing. Among its highly ranked graduate schools are its law school, whose first professor wrote the first draft of the United States Constitution, its medical school, the first in North America, and Wharton, the first collegiate business school. Penn's endowment is US$20.7 billion, putting it amongst the wealthiest academic institutions in the world, and its 2019 research budget was $1.02 billion. Penn was one of nine colonial colleges chartered before the U.S. Declaration of Independence when Benjamin Franklin, the university's founder and first president, advocated for an educational institution that trained leaders in academia, commerce, and public service. The campus, in the University City neighborhood of Philadelphia, is centered around College Hall, and notable landmarks are Houston Hall, the first modern "student union", and Franklin Field, the first double-decker college football stadium. Penn also is the home of the Morris Arboretum, the official arboretum of the Commonwealth of Pennsylvania, which is located 15 miles northwest of the campus, in the Chestnut Hill section of Philadelphia. The university's athletics program, the Quakers, fields varsity teams in 33 sports as a member of the NCAA Division I Ivy League conference.
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