BristolMyers Squibb

Senior Manager, PDS BI&T Architecture & Components

BristolMyers Squibb$134K — $163K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's or Master's degree in Computer Science, Engineering, AI, Data Science, or a related field.
  • 6+ years of software engineering experience with deep full-stack delivery.
  • Strong Python skills, specifically with async patterns.
  • Production experience with async web frameworks like FastAPI, and understanding of event-driven architectures.
  • Strong knowledge of modern web frontends (React) and micro-frontend composition.
  • Experience designing distributed, multi-service systems and building internal platforms.
  • Experience with agentic orchestration frameworks and cloud LLM provider integration.

Responsibilities

  • Architect distributed, multi-service platforms that integrate autonomous services.
  • Design an internal SaaS/PaaS with shared SDKs and reusable components.
  • Build orchestration workflows utilizing LLM reasoning and enterprise security.
  • Create reusable libraries and patterns supporting various business domains.
  • Develop FastAPI applications with real-time streaming capabilities.
  • Design APIs for service communications and orchestration.
  • Implement error handling and enterprise security for containerized services.

Benefits

  • Work in a highly technical, collaborative environment with multidisciplinary teams.
  • Hands-on role focusing on significant architecture and design challenges.
  • Opportunities for innovation in AI and analytics solutions.
  • Contribute to shaping the future of digital product delivery within a global organization.
Full Job Description

Senior individual-contributor role on the Architecture and Components team; works alongside a multidisciplinary group (UI, UX, AI Engineering, Full Stack, Architecture) within a globally distributed organization. This role does not manage people.

Organizational Context

As BMS Product Development & Supply (PDS) accelerates delivery of digital products and digital workers through Fusion Teams and scales adoption via Intelligence Hub, the organization requires clear ownership of architecture, reusable components, and technical decision-rights.

The Analytics & AI Enablement (A&AIE) Architecture & Components Team is a highly technical team responsible for defining how digital solutions are built, ensuring they are scalable, operable, and future-ready through PDS Aim Points, with ambitions to revolutionize PDS use of AI by 2030 60 1035. Rather than delivering individual use cases, this team establishes and stewards the shared architectural foundations and components 60including those used for the foundational data pipelines, analytical models, and business-facing reports and dashboards 60that enable broad, consistent execution across PDS.

Position Summary

This senior individual-contributor role will architect and build the shared, full-stack platform that powers analytics, digital products, and digital workers across PDS. The role focuses on distributed, multi-service systems that combine an orchestration layer, autonomous agents, shared services, and a federated frontend into a single internal platform-as-a-service 60treated as reusable foundations rather than one-off use cases.

You will work end to end, from async backend services and APIs through to modern web frontends, and you will design platforms that go beyond conversational interfaces to deliver autonomous analytical workflows, standardized tool-calling, and composable UI experiences. This is a deeply hands-on, principal-level technical authority role; you set the bar through architecture, reference implementations, and engineering excellence.

Key Responsibilities

Platform & Multi-Service System Architecture

  • Architect distributed, multi-service platforms that orchestrate work across autonomous services and agents, with conditional routing, parallel execution, and error recovery.
  • Design the platform as an internal SaaS/PaaS: shared SDKs, service contracts, and reusable components that solution teams consume rather than rebuild.
  • Build graph-based orchestration workflows combining LLM reasoning, business logic, real-time data integration, and enterprise security patterns.
  • Create reusable node/component libraries and extensible platform patterns supporting multiple business domains.

Backend Development & API Design

  • Build production FastAPI (or similar) applications with async I/O patterns for persistence and external services.
  • Implement Server-Sent Events (SSE) and WebSocket protocols for real-time streaming responses.
  • Design APIs and event-driven architectures for orchestration and service-to-service communication.
  • Develop robust error handling, graceful degradation, and enterprise security integration (SSO, access control), deploying containerized services via CI/CD.

Frontend & Unified Experience

  • Build modern web frontends (e.g., React) and design micro-frontend / Module Federation composition so independently built modules form one coherent experience.
  • Develop and steward a shared component library and design system used across the platform.
  • Design AI-enhanced UI patterns for streaming responses, chat, and analytical/canvas visualization.

MCP Development & Dual-Intent Delivery

  • Make MCP development and hosting a first-class platform capability, ensuring every solution is dual-intent: delivered both as a full-stack web experience and through Claude Desktop.
  • Design, build, and host production MCP servers that expose platform services and tools so the same underlying capabilities power both the web UI and Claude Desktop, with no divergence between the two surfaces.
  • Define golden-path patterns, templates, and shared MCP servers (tools, resources, prompts, transport, and authentication) that solution teams reuse to ship dual-intent solutions quickly.
  • Establish MCP hosting, versioning, security, and operational standards for seamless, enterprise-grade integration with Claude Desktop.

LLM Integration, Orchestration & Tool Calling

  • Integrate cloud LLM providers (AWS Bedrock or comparable) into platform services.
  • Design prompt management with versioning, templating, and dynamic compilation.
  • Implement conversation/state persistence (e.g., Redis checkpointing) for multi-turn workflows.
  • Build standardized tool-calling that connects agents and external clients to data sources and services, with the Model Context Protocol as the primary integration surface.

Reusability, Observability & Optimization

  • Treat internal developers as customers: provide golden-path templates, clear contracts, and documentation that accelerate delivery.
  • Define standards for versioning, contracts, and backward compatibility across the component ecosystem.
  • Integrate observability and tracing; build monitoring for performance, latency, cost, and quality, and optimize resource and token usage across production workflows.

Cross-Functional Collaboration

  • Partner with cloud, AI, data, and UX engineers on the team to integrate full-stack work with infrastructure, agentic capabilities, and interaction design.
  • Partner with Enterprise engineering and governance teams to align standards, controls, and shared services.
  • Provide technical mentorship on solution patterns, system design, and platform best practices, and contribute to architecture reviews and documentation.

Desired Experience | Required

  • Bachelor's or Master's degree in Computer Science, Engineering, AI, Data Science, or a related field.
  • 6+ years of software engineering experience with deep full-stack delivery, including production experience building LLM-powered or agentic applications.
  • Strong Python, including async patterns (asyncio, async/await) and Python-based automation.
  • Production experience with async web frameworks (FastAPI or similar), REST, and event-driven / streaming architectures (WebSocket/SSE, queues, streams).
  • Strong working knowledge of modern web frontends (React) and micro-frontend / Module Federation composition; deep frontend and design-system expertise a strong plus.
  • Experience designing distributed, multi-service systems with well-defined contracts between components, and building an internal platform, SaaS/PaaS, or shared developer platform.
  • Experience with agentic orchestration frameworks (LangGraph preferred; LangChain, CrewAI, Autogen, or similar) and integration with cloud LLM providers (AWS Bedrock, Azure OpenAI, Anthropic, or OpenAI), including onboarding and standardizing these frameworks for solution teams.
  • Strong platform and cloud depth: Docker and Kubernetes / Amazon EKS, infrastructure-as-code (CloudFormation), Git and CI/CD, service mesh, policy-as-code (OPA/Gatekeeper), and production observability (e.g., Prometheus, Grafana, Loki) on AWS (Azure and/or GCP a plus).
  • Experience owning platform governance, security, and self-service onboarding for a shared platform 60IAM/SSO, group-based authorization, and policy-as-code 60acting as a technical gatekeeper for the teams that consume it.

Critical Platform & Agentic Systems Experience

  • Built autonomous, multi-step systems performing analytical tasks beyond simple chatbots.
  • Designed distributed platforms with service orchestration, conditional logic, and state management.
  • Developed and hosted production MCP servers with demonstrated adoption across capabilities.
  • Delivered dual-intent solutions where the same services power both a web experience and an LLM/desktop client via MCP.
  • Implemented standardized tool-calling for external system integration.
  • Designed shared SDKs/contracts and managed API/contract evolution across many consumers.
  • Prompt engineering at scale (templating, versioning, optimization) and understanding of agentic design patterns (ReAct, Plan-and-Execute, tool-use agents).
  • Strong problem-solving, communication, and ability to set technical direction and influence in globally distributed teams.

Ideal Candidates Would Also Have

  • Prior experience in global life sciences, pharma, or supply chain 60especially in Product Development & Supply (PDS).
  • Experience in regulated environments (GxP, GDPR, PII) and embedding compliance into platform design.
  • Experience scaling an internal platform across multiple product/domain teams and managing the resulting contract and dependency surface.
  • Experience working internationally with globally dispersed teams.

Other Quali

About BristolMyers Squibb

BristolMyers Squibb Careers

Join the vibrant team at BristolMyers Squibb, a leader in global biopharmaceutical innovation, where your career growth is as important as the life-changing solutions we develop. At BristolMyers Squibb, we are committed to fostering a diverse and inclusive workplace that encourages professional growth and development. Work You’ll Do Embark on a career with BristolMyers Squibb and be part of a company that’s dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. With us, you’ll contribute to a culture that embraces scientific innovation, responsible leadership, and community outreach. Explore job opportunities in various fields from research to marketing, and join a team that values leadership and diversity. Our commitment to career growth means we support your journey with extensive training programs, leadership development opportunities, and a global, diverse network of professionals. Innovative Work At BristolMyers Squibb, innovation is at the core of everything we do. From pioneering research in oncology to breakthroughs in immunology, our professionals have the opportunity to make significant contributions to the field and impact lives globally. Our collaborative environment encourages team members to challenge the status quo and bring forward ideas that pave the way for groundbreaking solutions. Be Part of a Great Team Working at BristolMyers Squibb means being part of a team that supports your aspirations and shares your values. Our culture thrives on teamwork, respect, and diversity, creating a workplace where everyone can achieve their potential. Enjoy the benefits of being part of a company that values work-life balance, provides competitive benefits, and fosters an environment where skills and leadership are developed through hands-on experience and comprehensive mentorship programs. Future-Proof Your Career With a multitude of job opportunities ranging from internships to full-time positions, BristolMyers Squibb is not just hiring; we’re building futures. We equip our employees with the tools needed for success, including advanced training in diverse skill sets, leadership programs, and opportunities for professional networking and growth. Stay Connected Join Our Team Search open positions that match your skills and interests. We are looking for passionate, curious, and innovative team players who are ready to make a difference. Explore our career portal for all current job listings and be sure to submit your resume. Keep Up to Date Stay informed with the latest company news, career tips, and industry insights from BristolMyers Squibb. Our careers blog is a resource for potential and current employees looking to maximize their career potential. Job Alert Emails Customize your subscription to receive job alerts and insider information tailored to your preferences. Discover the exciting and rewarding career opportunities that await at BristolMyers Squibb. At BristolMyers Squibb, your career is just the beginning – it’s a pathway to personal and professional fulfillment. Join us and make a global impact.
Learn more about BristolMyers Squibb
Size
32,200 employees
Market Cap
$156.3 billion
Industry
Net Income
-$9 billion
Founded
1887
5 Year Trend
+19%
Revenue
$42.5 billion
NASDAQ

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