Vaxcyte

Senior IT Systems Analyst, G&A

Vaxcyte$164K — $191K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in computer science or related field, with 7+ years' experience in enterprise applications, particularly HR systems.
  • Hands-on experience with API integrations and data transformation techniques.
  • Strong data analysis capabilities with the ability to perform data validation and reconciliation.
  • Deep understanding of SDLC practices and IT controls, especially relating to SOX compliance and audits.
  • Proven skills in business process mapping and translating complex needs into functional requirements.

Responsibilities

  • Serve as the primary IT contact for G&A stakeholders to gather and document business needs.
  • Document and translate current-state and future-state processes into functional requirements.
  • Support compliance controls including SOX audits and access reviews for G&A systems.
  • Drive SDLC best practices for technology delivery to ensure quality and consistency.
  • Facilitate alignment between HR, IT, and G&A teams on project scope and outcomes.

Benefits

  • Comprehensive health and wellness benefits.
  • Flexible working environment with hybrid work options.
  • Opportunities for professional development and growth.
  • Equity component in compensation package.
Full Job Description
Summary:

Sr. IT Systems Analyst, G&A is responsible for leading the architecture, design, and evolution of G&A platforms, with a strong focus on scalable process design and cross-system integration. This role partners with HR, IT and other G&A teams to implement and support end-to-end business processes, establish architectural standards, and contribute to technology decisions that enable efficiency and growth. The analyst ensures platform reliability, data integrity, and seamless operations while delivering strategic enhancements and managing system releases in alignment with organizational priorities. This is a hands-on role that reports to the Associate Director of Enterprise IT Systems at Vaxcyte's San Carlos, California headquarters.
Essential Functions:
  • Serve as an IT point of contact for G&A stakeholders; gather, analyze, and document business needs for processes and systems.
  • Document current-state and future-state processes; translate business needs into functional requirements, and system specifications.
  • Support governance and compliance controls (e.g., SOX ITGC where applicable), including access reviews, role/permission audits, segregation of duties considerations, and evidence documentation.
  • Support recurring reporting cycles and audit requests by ensuring data quality, traceability, and timely delivery of requested information.
  • Drive SDLC standards and best practices for technology delivery (intake, requirements, design, testing, release, and documentation) to improve consistency, quality, and auditability.
  • Facilitate communication between HR, IT, other G&A teams and implementation partners to align on scope, priorities, timelines, and outcomes.
  • Support implementation of new features and releases, including test planning, test script creation, UAT coordination, regression testing, rollout planning, and post-go-live stabilization.
  • Develop and maintain support materials, training content, job aids, and end-user documentation to drive adoption and consistent process execution.
  • Ensure G&A systems are operated in accordance with IT policies and procedures, privacy/security expectations, and applicable regulatory requirements.
  • Manage governance for change management across the responsible G&A ecosystem (e.g., change intake and prioritization, change calendar, risk/impact assessment, approvals/CAB as applicable, communications, and release readiness).
  • Develop and maintain documentation (requirements, process flows, training, end-user guides) and deliver enablement as needed.
Requirements:
  • Bachelor's degree in computer science, information systems, or related field. Minimum 7 years of experience supporting enterprise applications, including HR systems (Workday), contingent workforce management solutions, and other G&A systems. Other combinations of education and/or experience may be considered.
  • Hands-on experience with integrations (e.g., API-based integrations, SFTP/file-based interfaces, data mapping/transformations, monitoring, error handling, and reconciliation).
  • Strong data analysis skills: ability to validate data, reconcile results, and perform basic queries.
  • Strong understanding of SDLC practices and IT controls (ITGC), including security and compliance expectations; experience supporting SOX controls and audit evidence collection.
  • Strong analytical, troubleshooting, and problem-solving skills.
  • Business process mapping experience (current-state/future-state), including documenting end-to-end processes and identifying control points.
  • Ability to translate complex business needs into clear functional requirements and technical-ready specifications.
  • Excellent communication and stakeholder management skills; able to translate between business and technical teams and produce clear documentation.
  • Comfort working in a fast-paced, evolving environment with cross-functional teams.
  • Highly motivated, results-focused, and able to manage multiple priorities with a sense of urgency.
  • Experience working with GxP validated systems, supporting CSA/validation documentation, change control, deviation/CAPA support, and inspection/audit readiness is a plus.
  • Life Sciences industry experience is a plus.

Reports to: Associate Director, IT Enterprise Systems

Location: San Carlos, CA; Ability to be onsite 2 to 3 days a week.

Compensation:

The compensation package will be competitive and includes comprehensive benefits and an equity component.

Salary Range: $164,000 - $191,000 (SF Bay Area). Salary ranges for non-California locations may vary.

About Vaxcyte

Vaxcyte is a clinical-stage biotechnology company developing a new generation of vaccines to address some of the most important and deadly infectious diseases worldwide. The company's cell-free protein synthesis platform, comprising the XpressCFTM platform, is capable of rapidly generating protein antigens that can be used in vaccines to protect against bacterial and viral pathogens. Vaxcyte's lead vaccine candidate, VAX-24, is a preclinical, 24-valent pneumococcal conjugate vaccine (PCV) being developed for the prevention of pneumococcal disease. The company is also developing VAX-XP, a PCV with expanded serotype coverage, as well as vaccines for Group A Streptococcus, Group B Streptococcus, and Lyme disease.
Learn more about Vaxcyte
Size
89 employees
Market Cap
$3.6 billion
Industry
Founded
2013
NASDAQ

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