Moderna, Inc.

Senior Bioinformatics Engineer II

Moderna, Inc.$145K — $234K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in Computer Science, Engineering, or a related field with 10+ years of relevant work experience
  • Strong programming skills in Python and Linux
  • Excellent problem-solving and analytical skills
  • Ability to work independently and collaboratively
  • Experience with bioinformatics workflow frameworks (e.g., NextFlow, Luigi, Snakemake), version control systems (Git), Cloud services (AWS), and containers (Docker)
  • Experience with Computer System Validation processes
  • Familiarity with GxP environments and regulatory compliance requirements

Responsibilities

  • Monitor bioinformatics pipelines and software systems for standards compliance and recommend corrective actions.
  • Support development and implementation of quality assessment methods and procedures.
  • Collaborate with teams to design and enhance automated testing capabilities.
  • Maintain scientific software platforms for reliable performance.
  • Troubleshoot and resolve software and operational issues.
  • Support computer system validation by drafting and executing qualification documentation.
  • Provide on-call support for urgent operational issues.

Benefits

  • Competitive healthcare and voluntary benefit programs
  • Access to fitness, mindfulness, and mental health support
  • Family planning benefits including fertility and adoption support
  • Generous paid time off including vacation and global recharge days
  • Savings and investment planning resources
  • Location-specific perks and extras
Full Job Description
The Role

In this role, you will help ensure the reliability, quality, and compliance of critical bioinformatics pipelines that support Moderna's scientific and operational objectives. Working at the intersection of bioinformatics, software engineering, validation, and operational support, you will monitor system performance, identify deviations from established standards, and drive continuous improvements across the software ecosystem.

You will play a key role in maintaining continuous software operations, supporting validation activities, enhancing automation capabilities, and collaborating with multidisciplinary teams to strengthen the robustness of scientific software platforms. This position also offers exposure to advanced digital technologies and opportunities to work alongside teams leveraging automation, data-driven processes, and emerging Generative AI-enabled solutions to improve operational efficiency.

Here's What You'll Do
  • Monitor bioinformatics pipelines and scientific software systems to identify deviations from established standards and recommend corrective actions.
  • Support the development, refinement, and implementation of standards, methods, and procedures used to assess software quality and operational readiness.
  • Collaborate closely with bioinformatics and software engineering teams to design, develop, and enhance automated testing capabilities that support continuous operation of bioinformatics pipelines.
  • Monitor and maintain scientific software platforms to ensure reliable and uninterrupted performance.
  • Troubleshoot, investigate, resolve, or appropriately annotate software and operational issues to support efficient incident management.
  • Support computer system validation activities through the drafting, execution, and maintenance of qualification scripts, protocols, and associated validation documentation.
  • Work independently and in partnership with development teams to identify software defects, resolve bugs, and implement system improvements.
  • Provide on-call support to address urgent operational issues and minimize downtime.
  • Develop, maintain, and continuously improve documentation related to software troubleshooting, issue investigation, issue resolution, and operational procedures.
  • Improve and automate error reporting applications to increase visibility, efficiency, and system reliability.
  • Continuously expand technical knowledge of scientific software platforms, bioinformatics technologies, and supporting infrastructure.
  • Contribute to a culture of operational excellence, continuous improvement, compliance, and high-quality software delivery.


The key Moderna Mindsets you'll need to succeed in the role:
  • "We obsess over learning. We don't have to be the smartest we have to learn the fastest."
  • "We digitize everywhere possible using the power of code to maximize our impact on patients."


Here's What You'll Need (Minimum Qualifications)
  • Bachelor's degree in Computer Science, Engineering, or a related field and 10+ years of relevant work experience
  • Strong programming skills, particularly in Python and Linux
  • Excellent problem-solving and analytical skills
  • Ability to work independently and as part of a team
  • Experience using a bioinformatics workflow framework (e.g. NextFlow, Luigi, Snakemake, NextFlow preferred), version control systems (Git preferred), Cloud (AWS preferred) and containers (Docker preferred)
  • Experience with Computer System Validation processes.
  • Experience in a GxP environments and knowledge of regulatory compliance requirements


Here's What You'll Bring to the Table (Preferred Qualifications)
  • Experience with bioinformatics software and an understanding of neoantigen therapies
  • Proven experience in software quality assurance and quality control
  • Effective time management, organization, and planning skills
  • Flexibility; adaptability to frequent change
  • Results oriented; ability to manage performance.
  • Effective communication, both written and verbal
  • Personal and shared accountability
  • A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.


Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That's why our benefits and well-being resources are designed to support you-at work, at home, and everywhere in between.
  • Competitive healthcare, plus voluntary benefit programs to support your unique needs
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
  • Family planning benefits, including fertility, adoption, and surrogacy support
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
  • Savings and investments to help you plan for the future
  • Location-specific perks and extras

The salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual's position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

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