Career CategoryResearch
Job DescriptionScientist What you will doLet's do this. Let's change the world.
Amgen is seeking a Scientist to join the Pathology Laboratory within the Translational Safety & Risk Sciences (TSRS) Department in South San Francisco, California. The Scientist will develop and apply tissue-based assays, including multiplex assays and digital image analysis, to support target expression studies, preclinical model development, pharmacodynamics, efficacy, and biomarker discovery.
Responsibilities:- Develop, optimize, validate, and standardize histopathology assays using FFPE samples, including single-plex and multiplex immunohistochemistry (IHC) and in situ hybridization (ISH) in colorimetric and immunofluorescent formats.
- Use imaging modalities and digital pathology tools to generate, analyze, and interpret tissue-based data for target qualification, pharmacodynamic and efficacy assessments, and biomarker development.
- Collaborate with pathologists, research investigators, and translational teams to deliver high-quality data supporting mechanism-of-action studies, in vivo model development, and toxicity assessments across therapeutic areas.
- Maintain clear, complete documentation and communicate results through laboratory information systems, databases, and team presentations.
Basic Qualifications:Doctorate degree
OR
Master's degree and 2+ years of relevant research and industry experience
OR
Bachelor's degree and 4 years of relevant research and industry experience
Preferred Qualifications:- PhD or master's degree in cell biology, molecular biology, or related discipline.
- Two or more years of molecular pathology experience, preferably in an industry setting.
- Demonstrated expertise in pathology-based methods, including IHC, multiplex IHC, ISH and immunofluorescence imaging.
- Experience with digital pathology and image analysis, preferably using HALO and/or Visiopharm.
- Experience with automated staining platforms, such as Ventana, Leica Bond, or IntelliPATH, is preferred.
- Ability to manage multiple projects and priorities simultaneously.
- Excellent written and verbal communication skills.
Qualifications- Experience analyzing pathology imaging data, including H&E, IHC, multiplex immunofluorescence, and/or spatial transcriptomics.
- Familiarity with whole-slide imaging and digital pathology platforms, such as HALO or Visiopharm, is preferred.
- Understanding of machine-learning methods for image segmentation, classification, detection, and representation learning.
- Strong communication, organizational, and collaboration skills in multidisciplinary scientific environments.
What you can expect of usAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.careers.amgen.comIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadlineExternal/Internal postings: Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Internal only posting (or Pre-ID candidate): Amgen anticipates accepting applications however, we may continue accepting applications beyond this date if we do not receive a sufficient number of candidates.
SponsorshipSponsorship for this role is not guaranteed.
Salary Range129,404.00USD -175,076.00 USD
