Neurocrine Biosciences, Inc.

Scientific Director, Bioconjugation Development

Neurocrine Biosciences, Inc.$185K — $253K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • BS/BA in chemistry, biochemistry, biology, or similar field with 12+ years of experience, or MS/MA with 10+ years, or a PhD with 8+ years
  • Expertise in bioconjugate development strategies and late-stage bioconjugate development
  • Extensive manufacturing and commercialization experience in bioconjugates
  • Comprehensive knowledge of regulatory requirements for bioconjugate therapeutics
  • Proven cross-functional leadership across discovery, CMC, quality, and regulatory functions

Responsibilities

  • Lead strategic initiatives in bioconjugation development across the portfolio
  • Establish the long-term scientific vision for ADC, APC, and AOC development
  • Design and execute departmental policies for bioconjugates
  • Maintain oversight of functional deliverables and risk management strategies
  • Drive cross-functional initiatives impacting discovery, manufacturing, and regulatory functions
  • Manage strategic relationships with external manufacturing partners
  • Lead innovation in bioconjugation technologies and platforms

Benefits

  • Retirement savings plan with company match
  • Paid vacation, holiday, and personal days
  • Paid medical, caregiver, and parental leave
  • Health benefits including medical, dental, and vision coverage
  • Eligibility for annual bonuses and equity incentive programs
Full Job Description
About the Role:
Set the long-term scientific vision for bioconjugation development, shaping portfolio strategy for next-generation antibody-drug conjugates (ADCs), antibody-peptide conjugates (APCs), antibody-oligonucleotide conjugates (AOCs), and related targeted delivery platforms. This leadership role drives innovation in conjugation technologies, linker-payload design, manufacturability, and product development, while strengthening external scientific engagement and ensuring deep product understanding, CMC excellence, and regulatory credibility remain central to organizational decision-making. By guiding functional development and aligning bioconjugation strategy with business priorities, you will have broad impact on both current programs and future platform development.

Your Contributions (include, but are not limited to):
  • Lead teams driving strategic bioconjugation development initiatives across the portfolio
  • Establish long-term scientific vision for ADC, APC, AOC, and emerging bioconjugate modalities, influencing enterprise strategy
  • Lead design and execution of departmental strategies and policies for bioconjugate process development
  • Maintain strategic oversight of functional deliverables
  • Drive cross-functional initiatives with department-wide impact across discovery, manufacturing, quality, and regulatory functions
  • Develop and oversee enterprise-level risk management strategies for bioconjugate products, platforms, and manufacturing processes
  • Manage external manufacturing partnerships strategically
  • Lead innovation initiatives across bioconjugation technologies, linker chemistries, payloads, and targeted delivery platforms
  • Guide strategic direction of multiple development programs from candidate selection through commercialization
  • Influence enterprise-level decision making
  • Develop functional capabilities and leadership talent in bioconjugation development
  • Perform other duties as assigned


Requirements:
  • BS/BA in chemistry, biochemistry, biology, or similar scientific discipline and 12+ years of relevant experience OR
  • MS/MA in chemistry, biochemistry, biology, or similar scientific discipline and 10+ years of relevant experience OR
  • PhD in chemistry, biochemistry, biology, or similar scientific discipline or equivalent and 8+ years of relevant experience
  • Expert in bioconjugate development strategies including site-specific conjugation technologies, DAR control, and late stage/commercial bioconjugate development
  • Extensive experience with bioconjugate manufacturing, technology transfer, and commercialization
  • Comprehensive regulatory knowledge for bioconjugate therapeutics
  • Advanced cross-functional leadership across discovery, CMC, quality, regulatory, and external partner organizations
  • Guides enterprise-level bioconjugation development initiatives and platform strategies
  • Demonstrates strategic execution excellence in advancing complex programs
  • Drives the strategic direction of the functional area
  • Broad scientific mastery guiding organizational leadership
  • Widely recognized scientific authority in bioconjugation, conjugation chemistry, or related disciplines
  • Deep understanding of business strategy and corporate objectives
  • Communicates scientific direction across the organization
  • Translates strategy into actionable plans
  • Leads multiple teams effectively
  • Mentors mid-level leaders
  • Exceptional communication and influence skills
  • Develops long-term organizational vision
  • Strong executive-level project leadership
  • Shapes organizational practices strategically
  • Influences external stakeholders


#LI-LS1

The annual base salary we reasonably expect to pay is $185,600.00-$253,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

About Neurocrine Biosciences, Inc.

Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company dedicated to discovering, developing and delivering life-changing treatments for people with serious, challenging and under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, with three pivotal and five early-stage clinical programs in multiple therapeutic areas. (*in collaboration with AbbVie)
Learn more about Neurocrine Biosciences, Inc.
Size
900 employees
Market Cap
$11.6 billion
Industry
Net Income
$407.3 million
5 Year Trend
+137.5%
Revenue
$1 billion
NASDAQ

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