BigHat Biosciences

Research Associate II, Production

BigHat Biosciences$88K — $100K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • BS in Biology or Chemistry with 2+ years of industry experience
  • Experience in laboratory method development and optimization
  • Hands-on experience with automated liquid handlers
  • Familiarity with molecular biology techniques and lab practices
  • Strong interpersonal and communication skills
  • Excellent documentation and record-keeping abilities

Responsibilities

  • Perform high-throughput processing on the BigHat platform
  • Contribute to scaling up production-grade data generation
  • Support in-house reagent manufacturing efforts
  • Execute experiments to optimize platform performance
  • Maintain detailed records of experiments and communicate results
  • Collaborate on standard operating procedures for sample processing
  • Identify and implement process improvements in laboratory systems
  • Operate automated liquid handlers and analytical instruments

Benefits

  • Full-time employment
  • Involvement in cutting-edge antibody production technology
  • Opportunity to contribute to innovative research
  • Collaboration in a dynamic team environment
  • Potential for career growth within a fast-paced start-up
Full Job Description
Research Associate II, Production

Department: Lab Science

Employment Type: Full Time

Location: San Mateo, CA

Description

The role: BigHat Biosciences is seeking a self-motivated individual for a Research Associate II, Production role to power our high-throughput, automated platform for antibody production and deep molecular characterization.

Key Responsibilities
  • Perform automated and manual high-throughput processing on the BigHat platform, including DNA preparation, protein expression, and protein characterization.
  • Contribute to the scaling up of BigHat's platform and production-grade data generation.
  • Support BigHat's Platform Reagents & Assay Support (PRAS) function by contributing to in-house reagent manufacturing efforts.
  • Execute experiments to optimize the performance efficiency of BigHat's platform.
  • Keep a detailed record of all experiments using BigHat's documentation tools, and clearly communicate results and challenges.
  • Collaborate on the creation of laboratory standard operating procedures (SOPs) for sample processing.
  • Collaborate closely with BigHat team members to identify, design, and implement critical process and operational improvements to production workflows and laboratory systems.
  • Operate automated liquid handlers and analytical instruments to ensure all lab and platform operations run efficiently.


Skills Knowledge and Expertise
  • BS in Biology or Chemistry, with 2+ year(s) of industry experience
  • Experience in process execution, laboratory method development, optimization, and troubleshooting.
  • Ability and willingness to work specific workday schedules as needed, for example 7AM to 3PM or 10AM to 6PM.
  • Hands-on experience with, or interest in, automated liquid handlers (e.g. Hamilton, OpenTrons, Tecan, Agilent systems). Experience with LIMS is a nice-to-have.
  • Experience with molecular biology techniques and general lab practices.
  • Efficient time management and ability to work on several projects simultaneously, in a dynamic start-up environment.
  • Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
  • Excellent record keeping abilities to document experimental work and analytical data.
  • Nice-to-haves include previous experience working with barcoding systems, inventory tracking, and experience with Google Workspace tools (Docs, Sheets, Slides, etc.)


Total Rewards

The salary estimated for this position is $88,000 - $100,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

About BigHat Biosciences

BigHat Biosciences is a biotechnology company that develops protein therapeutics using machine learning. The company's platform enables the rapid design and optimization of protein therapeutics, and is used to develop treatments for a variety of diseases, including cancer and autoimmune disorders. BigHat's technology is designed to be scalable, efficient, and cost-effective, and is used by pharmaceutical companies and academic researchers.
Learn more about BigHat Biosciences
Size
20 employees
Industry
Founded
2015

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