Job title: mRNA Analytical Development Senior Scientist
About the jobIn order to strengthen the Biochemical and Biophysical group in R&D Analytical Sciences Department, Sanofi Pasteur is looking for a skilled and highly motivated individual to develop novel methods and improve characterization of mRNA vaccines in development by working closely with the bioprocess development group.
Analytical Sciences Department has the overall responsibility to develop, qualify and validate robust analytical methods to support release and characterization testing of mRNA Drug Substances and Drug Products candidates in development.
Main Responsibilities:- Develop advanced technology for biochemical, biophysical, and bioassay assay development in support of mRNA vaccine process and product development, product release, stability, and comparability study.
- Work with analytical leads supporting CMC activities.
- Write and review method documentation and characterization reports in support of regulatory filings.
- Ensure timely completion of assignments and deliverables. Independently design and execute complex experiments. Author method development and investigation reports.
- Manage assay testing at CROs if required, support investigation, deviation, and change control.
- Participate internal non-GMP and GMP lab set up and product release and stability testing.
- Supervise and train junior scientists.
- Compliant to Sanofi Quality standards and HSE policy. Participate in continuous improvement of laboratory safety and quality compliance.
About youBasic Qualifications- PhD or Master's Degree in Biochemistry, Biology, Cell Biology, Analytical Chemistry, Biotechnology or related sciences.
- Ph.D. with a minimum of 3 years of experience in the pharmaceutical or biotechnology industry, or a Master's degree with a minimum of 6 years of experience in the pharmaceutical or biotechnology industry.
- Previous CMC analytical development experience.
- Expertise in LC (RP, IEX, SEC, HILIC) and one or more of the following techniques but not limited to CGE, spectroscopy, particle analysis.
- Ability to perform complex method development and propose appropriate method improvement suitable for CMC space.
Preferred- Knowledge of nucleic acid/oligonucleotides chemistry and standard analytical methods of these molecules.
- LC-MS experience.
- Hands on experience in quality control laboratory environment is a plus.
Why choose us?- Bring the miracles of science to life alongside a supportive, future-focused team.
- Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
- Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
- Help improve the lives of millions of people globally by making drug development quicker and more effective.
- Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.
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Pursue progress, discover extraordinaryBetter is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people.
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US and Puerto Rico Residents Only
The salary range for this position is:
$100.500,00 - $145.166,66
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
