Bachelor's in Statistics, Mathematics, Computer Science, or a related field.
5+ years of related experience, with at least 3 years in Clinical Trial analysis.
At least 3 years of R programming experience, including package development.
Proficient in R programming, including building and maintaining packages.
Experience in analysis dataset and TLF generation.
Responsibilities
Lead and oversee statistical programming deliverables, ensuring data integrity and regulatory compliance.
Manage a team of statistical programmers, focusing on their technical and professional development.
Act as primary programming lead for regulatory submissions, ensuring all deliverables meet global standards.
Maintain programming infrastructure, including R package development and validation.
Develop R Shiny dashboards for data review and study monitoring.
Promote best practices in statistical programming development and validation.
Collaborate cross-functionally with Biostats, Data Management, and Clinical Science.
Benefits
Annual performance incentive bonus
Long-term equity awards
Comprehensive health benefits (medical, dental, vision)
401(k) with company match
Generous paid time off and company holidays
Additional wellness and work-life benefits
Full Job Description
This is an exciting opportunity to participate in advancing Natera's oncology product portfolio of cutting-edge diagnostic tests. As Manager of Statistical Programming, you will leverage your strong R programming skills and clinical trials background to contribute to the analysis and reporting of clinical trials supporting multiple regulatory submissions. Primary Responsibilities:
Lead and oversee statistical programming deliverables, including ADS (Analysis Datasets) and TLF (Table, Listings and Figures), ensuring data integrity and regulatory compliance with ICH, GCP, and FDA 21 CFR Part 11.
May manage a team of statistical programmers, taking responsibility for their technical and professional development, while contributing hands-on to programming work.
Act as primary programming lead for regulatory submissions (e.g., 510(k), CTA/CDx, and PMA), ensuring all deliverables meet rigorous global standards.
Maintain programming infrastructure, including R package development, validation, and maintenance in a controlled environment.
Develop R Shiny dashboards that support data review, study monitoring, and exploration of analysis results.
Promote statistical programming development and validation best practices.
Work cross-functionally with Biostats, Data Management, Clinical Science, and other functions as necessary.
Qualifications:
Bachelor's in Statistics, Mathematics, Computer Science, or a related field.
5+ years of related experience, with at least 3 years of experience in Clinical Trial analysis.
At least 3 years of R programming experience, including package development.
Knowledge, Skills, and Abilities:
Proficient in R programming, including building and maintaining packages.
Experience in analysis dataset and TLF generation.
Prior experience in NGS, genetics, and/or oncology diagnostics preferred.
Experience maintaining statistical computing environments a plus.
Compensation & Total Rewards
This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
This position is also eligible for additional compensation and benefits through Natera's robust Total Rewards program, including:
Annual performance incentive bonus
Long-term equity awards
Comprehensive health benefits (medical, dental, vision)
401(k) with company match
Generous paid time off and company holidays
Additional wellness and work-life benefits
Compensation Range
$145,200-$181,500 USD
About Natera
Natera is a biotechnology company that focuses on genetic testing and diagnostics. The company's products are designed to help diagnose and treat genetic diseases, cancer, and other conditions. Natera's pipeline includes products for reproductive health, oncology, and organ transplantation. The company was founded in 2003 and is headquartered in San Carlos, California.
