Manager of Project Management and Operational Excellence

Title:
Manager of Project Management and Operational Excellence
Job Type:
RegularCompany:
Health Research, Inc. (HRI) Roswell Park DivisionDepartment:
Center for ImmunotherapyTime Type:
Full timeWeekly Hours:
40
FTE:
1Shift:
First Shift (United States of America)

Summary:
The GMP Engineering and Cell Manufacturing Facility is seeking a Manager of Project Management and Operational Excellence to help build the processes, systems, and management infrastructure required to support the continued growth of GEM.
GEM is a rapidly expanding academic manufacturing organization supporting internal and external cell therapy, viral vector, plasmid, analytical, process development, and translational programs. As the number and complexity of customer programs increase, GEM requires a more consistent approach to project execution, cross functional coordination, performance management, capacity planning, and continuous improvement.

The Manager will lead complex projects across GEM, establish scalable project and operational processes, develop dashboards and key performance indicators, and improve visibility into timelines, resources, risks, financial performance, and customer deliverables. The position will also support GEM project managers and work closely with GEM leadership, functional managers, business development, Finance, Quality, Legal, Supply Chain, Facilities, and other institutional partners.

This position is intended to strengthen the operating systems that connect GEM's technical capabilities and enable the organization to scale efficiently while maintaining quality, accountability, financial discipline, and exceptional customer service.

The pay range for this position is $117,252 - $142,646 annually, this includes a comprehensive benefit package.

The listed pay range reflects the range of potential compensation for this role. The actual offer may vary based on qualifications, skills, and experience.

Qualifications:
Required Education and Experience:

1. Master's degree in business, healthcare administration or a related field and the equivalent of six (6) years of full-time experience in healthcare or business operations, including four (4) years engaged in project management activities; or
2. Bachelor's degree in business, healthcare administration or a related field and the equivalent of eight (8) years of full-time experience in healthcare or business operations, including four (4) years engaged in project management activities; or

NOTE: Degrees must be conferred by an accredited school, college, or university, or by an institution recognized by Roswell Park Comprehensive Cancer Center and/or Health Research Incorporated as adhering to acceptable educational standards.

Preferred Qualifications:

• Demonstrated experience leading complex, cross-functional projects and programs involving multiple departments, stakeholders, and competing priorities.
• Experience establishing and improving project management frameworks, including project governance, standardized processes, portfolio management, resource planning, risk management, and performance reporting.
• Hands-on experience with operational excellence and continuous improvement methodologies, including Lean, Six Sigma, value stream mapping (VSM), SIPOC, process flow mapping, root cause analysis, and process optimization.
• Demonstrated ability to assess existing business processes, identify operational gaps, design future-state workflows, and implement scalable systems and standardized procedures.
• Experience developing and implementing key performance indicators (KPIs), management dashboards, and reporting systems to monitor operational performance, project execution, resource utilization, financial performance, and organizational priorities.
• Experience with capacity planning, resource allocation, budget tracking, financial reporting, and forecasting across multiple projects or programs.
• Experience implementing or improving enterprise systems, project management platforms, business intelligence tools, or workflow automation solutions, such as Microsoft Project, Smartsheet, Power BI, Dynamics 365, ERP, CRM, or comparable systems.
• Demonstrated experience leading organizational change initiatives, facilitating cross-functional collaboration, and driving adoption of new processes, systems, and operating practices.
• Experience establishing clear roles, responsibilities, accountability structures, and communication processes across multidisciplinary teams.
• Experience mentoring, coaching, or providing functional leadership to project managers, project coordinators, or other professional staff.
• Strong analytical, organizational, communication, facilitation, and structured problem-solving skills, with demonstrated ability to engage senior leadership and translate strategic objectives into actionable operational plans.
• Project Management Professional (PMP), Lean Six Sigma, or comparable professional certification or training preferred.
• Experience in biotechnology, pharmaceutical manufacturing, healthcare, life sciences, contract manufacturing, or another complex, regulated, or project-driven organization preferred.

Grant Funding

This is a grant-funded position. Compliance with funding requirements such as time and effort reporting, grant deliverables, and contract deliverables is required.