Global Medical Affairs Lead, GI Oncology

Location: Gaithersburg, Maryland, United States
Working model: Hybrid, with an expected onsite presence three days per week
Travel: Approximately 30%, including domestic and international travel
Relocation support: May be available

We are seeking a Global Medical Affairs Lead, GI Oncology, to provide strategic medical leadership for our expanding hepatobiliary portfolio, including hepatocellular carcinoma and biliary tract cancer.

This is an opportunity to shape the medical strategy for a complex and evolving portfolio, prepare global markets for critical launches and contribute to the development of emerging treatment approaches, including next-generation molecules and novel modalities.

As the accountable medical leader assigns GI oncology indications and assets, you will shape and deliver the Global Medical Strategy, connecting Medical Affairs, R&D and Commercial teams to advance the portfolio and prepare markets for launch.

• Develop and execute Global Medical Plans, setting priorities and adapting strategy based on scientific developments, external insights and performance.
• Lead medical launch readiness and ensure global strategies are translated into relevant regional and country plans.
• Influence clinical development, evidence generation and lifecycle planning by representing Medical Affairs on key cross-functional teams.
• Identify evidence gaps and lead integrated evidence plans across clinical, real-world, diagnostic and digital sources.
• Shape Medical Affairs studies and lead global publication and scientific communication strategies.
• Develop a clear scientific narrative across publications, medical education, congresses and external engagement.
• Build strategic relationships with external experts, professional societies, health systems and other scientific organizations.
• Lead complex global matrix teams, build stakeholder alignment and strengthen Medical Affairs capabilities through coaching and mentorship.

• Advanced medical or scientific degree, such as an MD, PhD, PharmD or equivalent.
• +3 years of Medical Affairs experience within the pharmaceutical or biotechnology industry, typically gained at country, regional or global level.
• +3 years of demonstrated experience in oncology.
• +3 years of experience developing or leading Medical Plans, evidence-generation strategies, publications or scientific communication programs.
• +3 years of experience supporting an oncology launch or preparing a market for launch
• Demonstrated success working in a complex, cross-functional matrix involving Medical Affairs, R&D and Commercial stakeholders.
• Proven ability to influence senior stakeholders and translate scientific evidence into strategic recommendations.
• Experience engaging external experts and scientific communities.
• Strong scientific communication, stakeholder-management and leadership skills.

• Experience in gastrointestinal oncology, hepatocellular carcinoma, biliary tract cancer or another hepatobiliary malignancy.
• Experience in immuno-oncology or immunotherapy.
• Experience with new mechanisms of action, emerging treatment modalities, companion diagnostics or complex biomarker strategies.
• Exposure to novel modalities such as cell therapy or bispecific molecules.
• Experience leading matrix teams across complex or multi-indication portfolios.

Our Gaithersburg site brings together an international scientific community united by a passion for advancing science and improving patients’ lives. The collaborative environment encourages knowledge sharing, entrepreneurial thinking and cross-functional partnership.

Located near leading universities, research institutions and the Washington, DC area, Gaithersburg offers access to a vibrant scientific ecosystem as well as a diverse and welcoming community.

The annual base pay for this position ranges from $ 206,827.20 - $310,240.80 USD. The base pay offered may vary depending on individualized factors, including market location and the successful candidate’s job-related knowledge, skills and experience.

In addition, this position offers a short-term incentive bonus opportunity and eligibility to participate in AstraZeneca’s equity-based long-term incentive program, subject to the terms of the applicable plans.

Benefits include a qualified retirement program, paid vacation and holidays, paid leaves, and health benefits including medical, prescription drug, dental and vision coverage. Additional information regarding participation in these plans will be provided if an applicant receives an offer of employment.

Bring your Medical Affairs expertise, oncology experience and strategic leadership to a role where you can shape an emerging portfolio, influence the development and launch of innovative medicines, and help transform outcomes for people affected by gastrointestinal cancers.

Apply today and help us redefine the future of cancer care.

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