AstraZeneca

Global Clinical Head (Pulmonologist)- Executive Director

AstraZeneca$331K — $497K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • MD degree or equivalent with board-certification in pulmonology
  • 10+ years of pharma experience in clinical drug development
  • Expertise in clinical research specifically in COPD and bronchiectasis
  • Experience in leading large, complex studies including global Phase 3 trials
  • Proven ability in developing program strategies and managing timelines
  • Experience in global regulatory submissions and interactions with major health authorities
  • Demonstrated leadership and mentoring abilities in a matrix environment
  • Ability to effectively communicate across multiple organizational levels
  • Familiarity with AI tools for clinical development activities

Responsibilities

  • Lead overall clinical strategy for one or more products in the Infectious Disease pipeline
  • Develop medical/scientific strategies for clinical components of regulatory documents
  • Accountable for clinical content delivery in collaboration with the Clinical Project Team
  • Represent the Clinical Team on the Global Project Team discussing product strategies
  • Organize and conduct Advisory Boards with international Key Opinion Leaders
  • Cultivate cross-functional collaborations to enhance project outcomes
  • Mentor and lead teams of clinicians and scientists effectively

Benefits

  • 401(k) retirement plan
  • Paid vacation and holidays
  • Paid leave options
  • Health benefits including medical, dental, and vision coverage
  • Opportunity for short-term incentive bonus
  • Participation in equity-based long-term incentive programs
Full Job Description
As Global Clinical Head (Executive Director) you will have a unique opportunity to further elevate the Infectious Disease Unit in one of the world's most respected biopharmaceutical companies. The role holds a significant development opportunity for the successful candidate whilst contributing to the positive journey that AstraZeneca is on.

Accountabilities:

The Global Clinical Head (GCH) will have overall clinical leadership of one or more global products in the Infectious Disease pipeline specifically related to the prevention of infections in patients with chronic respiratory diseases. The GCH is also responsible for medical/scientific strategies for the clinical components of the Target Product Profile (TPP), Clinical Development Plan (CDP), and regulatory documents (e.g., briefing documents, CTD/BLA, core labelling texts). Within the Clinical Project Team, the GCH has accountability for the clinical, scientific, and value content and delivery of the medical components for the program to time and quality. The GCH will be the team's voice and representative on the Global Project Team that oversees the overall strategy of Infectious Disease Unit's products.

Essential Skills/Experience:
• Graduate of a recognized school of medicine with an MD degree or equivalent with board-certification in pulmonology
• Demonstrated clinical research expertise in Pulmonology (especially in COPD and bronchiectasis)
• Pharma industry experience in clinical drug development for at least 10 years
• Experience in early and late stage program development and trial conduct
• Developed/delivered in parallel multiple complex and/or large studies (e.g., including but not limited to global, pivotal Phase 3 efficacy studies)
• Demonstrated ability to lead the development of a program strategy (e.g., Clinical Development Plans) and be accountable for project plans, timelines, progress, and outcomes
• Writing and delivery of global regulatory submissions (e.g., NDA/BLA submissions, benefit/risk assessment) and interacting with major Health Authorities (e.g., FDA, EMA, PMDA, CDE)
• Demonstrated ability leading and motivating teams in a matrix environment
• Demonstrated ability to lead, coach, and mentor physicians and other clinical scientists
• Significant hands-on clinical drug development experience and scientific credibility
• Demonstrated ability to cultivate excellent cross-functional collaborations
• Demonstrated ability to effectively communicate at multiple levels of the organization
• Must demonstrate high integrity
• Organize and deliver Advisory Boards with international Key Opinion Leaders (KOLs)
• Demonstrated AI/digital mindset and experience applying AI-enabled and generative AI tools to support clinical development activities (e.g., data analysis, medical writing, clinical trial operational efficiency)

Desirable Skills/Experience:
• Infectious disease and/or vaccine expertise
• Named Investigator on a number of clinical trials
• Significant and consistent peer-reviewed publication track record

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base salary for this position ranges from USD 331,873.60 - 497,810.40. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted
19-Aug-2026

Closing Date
03-Sep-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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