MD, PhD, PharmD, or MS in a relevant scientific discipline
10+ years of experience in clinical science or research
5+ years of experience specifically in oncology
Proven track record in designing and managing clinical trials
Strong analytical skills with expertise in statistical analysis
Excellent communication skills for diverse audiences
Experience in a fast-paced work environment
Responsibilities
Contribute scientifically to clinical programs for effective study design and execution
Lead scientific oversight in early- and late-stage oncology trials
Collaborate with cross-functional teams to ensure quality in clinical program execution
Develop and review essential clinical documents like protocols and study reports
Interpret clinical, safety, and biomarker data to guide study strategies
Provide scientific input for regulatory submissions and health authority interactions
Cultivate a collaborative and rigorous scientific culture within the team
Benefits
Collaborative work environment
Opportunities for professional growth and development
Engagement in impactful clinical programs
Access to cutting-edge research and technologies
Supportive leadership and cross-functional partnerships
Full Job Description
Summary
Tango has an exciting opportunity to join the team as our Director, Clinical Sciences. This is a hands-on role with scientific contributions to one or more clinical development programs. The successful candidate will actively engage in the design, execution, analysis, and interpretation of clinical studies. You will ensure scientific rigor throughout study conduct, lead data review and analysis, and partner cross-functionally to advance clinical development programs. This role reports to the Executive Director, Clinical Sciences. Your Role:
Scientific contribution to one or more clinical programs to ensure the successful design, execution, and interpretation of clinical studies
Provide scientific leadership throughout the design, execution, analysis, and interpretation of early- and late-stage oncology clinical trials
Partner closely with Clinical Development physicians, Clinical Operations, Biostatistics, Clinical Pharmacology, Pharmacovigilance, Regulatory Affairs, Translational Medicine, and Medical Writing to ensure high-quality execution of clinical programs
Contribute to the development and review of key clinical documents, including protocols, investigator brochures, informed consent forms, clinical study reports, clinical development plans, and regulatory briefing materials
Interpret emerging clinical, safety, PK/PD, and biomarker data to inform study conduct, dose selection, expansion opportunities, and overall development strategy
Contribute scientific expertise to regulatory submissions and health authority interactions
Foster a collaborative, accountable, and scientifically rigorous culture within the Clinical Science function
Perform additional duties and responsibilities as required
What You Bring:
MD, PhD, PharmD, MS within a relevant scientific discipline
At least 10 years of experience in clinical science, or research
At least 5 years of experience in oncology
Demonstrated experience in designing and managing clinical trials, including knowledge of regulatory guidelines and GCP
Strong analytical skills with proficiency in statistical analysis and interpretation of clinical data
Excellent written and oral communication skills, with the ability to convey complex scientific concepts to diverse audiences
Experience working in a fast-paced environment
Salary range
$190,400-$285,600 USD
About Tango Therapeutics
Tango Therapeutics is a biotechnology company that develops targeted cancer therapies. The company's approach is based on a deep understanding of the genetic drivers of cancer, and it uses this knowledge to develop drugs that can selectively target cancer cells. Tango Therapeutics was founded in 2017 and is headquartered in Cambridge, Massachusetts. The company has partnerships with a number of other biotech and pharmaceutical companies, and it has received funding from a variety of sources, including venture capital firms and government agencies.
