Vertex Pharmaceuticals Incorporated
• $164K — $246K *Qualifications
Responsibilities
Benefits
Job Description
Job Title
Principal Business Analyst, Cell & Gene Therapy Commercial Technology
Role Summary
Vertex is seeking a Principal Business Analyst, Cell & Gene Therapy Commercial Technology to join the Data, Technology and Engineering (DTE)team and play a key role in shaping and supporting technology solutions for our Cell & Gene Therapy commercial organization. This individual will partner closely with commercial stakeholders and technology teams to define business needs, improve processes, and enable scalable digital capabilities that support scaling operations, order management, analytics, and end to end patient journey across multiple platforms and technologies.
The ideal candidate will bring strong business analysis expertise, deep stakeholder management skills, experience delivering AI and automationand supporting commercial functions within biotechnology, pharmaceuticals, or other regulated industries. This role requires a blend of strategic thinking, process optimization, and hands-on delivery support to ensure technology solutions align with business priorities and compliance expectations.
Work Model: Hybrid or on-site
Key Responsibilities
Partner with Commercial, Cell & Gene Therapy, and Technology stakeholders to understand business strategies, priorities, and operational challenges
Lead requirements gathering, business process analysis, and solution design for complex commercial technology initiatives
Translate business needs into detailed functional requirements, user stories, process maps, business rules, and solution recommendations
Support technology initiatives across key commercial domains such as patient services, order management, field enablement, commercial analytics, and data integration
- Partner with business and technical teams to help define and deliver AI and automation usecases aligned to business priorities
Analyze current-state and future-state business processes to identify opportunities for standardization, automation, and optimization
Facilitate cross-functional workshops and working sessions to align stakeholders on priorities, requirements, and solution outcomes
Collaborate with product managers, architects, developers, data teams, and vendors to ensure solutions meet business objectives and enterprise standards
Drive business readiness activities including testing support, user acceptance testing, training coordination, adoption planning, and change management
Ensure solutions align with relevant compliance, privacy, legal, promotional review, and regulated industry requirements
Develop and maintain high-quality documentation including business requirements, process flows, use cases, impact assessments, and traceability artifacts
Use data, metrics, and stakeholder feedback to evaluate solution effectiveness and support continuous improvement
Contribute to business analysis best practices across the commercial technology organization
Required Qualifications
Bachelors degree in Business, Information Systems, Life Sciences, Engineering, or a related field
Significant experience in business analysis, product delivery, process improvement, or related roles within biotechnology, pharmaceuticals, healthcare, or another regulated industry
Experience supporting commercial business functions and technology platforms, preferably in life sciences
Demonstrated ability to lead complex, cross-functional initiatives involving multiple business and technical stakeholders
Strong experience eliciting, documenting, validating, and managing business and functional requirements
Proven ability to analyze and improve business processes and translate them into technology-enabled solutions
- Experience supporting or contributing to automation, advanced analytics, AI-enabled, or digital transformation initiatives
Experience working across the system or product delivery lifecycle, including planning, requirements, testing, implementation, and post-go-live support
Excellent communication, facilitation, presentation, and stakeholder management skills
Strong analytical, problem-solving, and organizational abilities
Understanding of compliance and documentation expectations in regulated business environments
Technical Skills Required
Business and functional requirements documentation
Process mapping and business workflow analysis
User story creation and backlog refinement
Gap analysis and solution assessment
Data analysis, reporting, and dashboard requirements support
Stakeholder workshop facilitation
User acceptance testing support and test scenario development
Change management and training support
Familiarity with CRM and commercial technology ecosystems
- Understanding of AI-enabled business solutions, workflow automation, and process digitization concepts
Knowledge of Agile, Waterfall, or hybrid project delivery methodologies
Proficiency with tools such as Jira, Confluence, Visio, Microsoft Excel, PowerPoint, Word, and other collaboration platforms
Understanding of enterprise data flows, integrations, and commercial reporting environments
Preferred Skills
Experience supporting Cell & Gene Therapy commercial business models and technology capabilities, including Salesforce and AI
Knowledge of pharmaceutical or biotech commercial operations, including field engagement, market access, patient support, and launch planning
Experience with platforms such as CRM systems, data visualization tools, customer engagement platforms, and commercial analytics solutions
- Experience with AI use case definition, intelligent automation, workflow tools, or emerging digital technologies in support of business operations
Familiarity with patient services, specialty distribution, HUB operations, and reimbursement-related workflows
Experience with digital transformation, automation, and master data or system integration initiatives
Understanding of privacy, promotional, legal, and compliance considerations in commercial technology
Relevant certifications such as CBAP, PMI-PBA, Agile, Scrum, or Lean Six Sigma
Advanced degree in Business, Information Systems, Life Sciences, or a related discipline
#LI-hybrid #LI-JS1
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$164,400 - $246,600Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1.Hybrid: work remotely up to two days per week; or select
2.On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Our team will look into this right away.
