Expertise in mammalian cell culture and aseptic techniques
Experience with human iPSC reprogramming and differentiation
Strong organizational and project management skills
Excellent written and verbal communication abilities
Experience mentoring junior scientists or research staff
Responsibilities
Maintain and expand human iPSC cultures
Reprogram patient cells to generate new iPSC lines
Perform routine cell culture procedures
Differentiate iPSCs into hematopoietic stem cell types
Prepare media, reagents, and cell culture materials
Monitor cell morphology, viability, and culture quality
Assist with laboratory management and compliance
Benefits
Collaborative and innovative laboratory environment
Opportunities for mentoring and leadership
Access to cutting-edge technologies
Engagement in grant applications and scientific communications
Professional development in stem cell biology and related fields
Full Job Description
Job Description
The Associate Scientist is experienced in the conduct of research involving the understanding of human diseases and improvement of human health. May assist in the operation of the clinical laboratory. Engages in clinical investigation or other research, production, technical writing, and related activities, and may mentor less senior scientist and Associate Researcher staff.
Responsibilities
Maintaining and expanding human iPSC cultures.
Reprogramming patient cells to generate new iPSC lines.
Perform routine cell culture procedures, including passaging, freezing, thawing, and cell counting.
Perform differentiation of iPSCs into hematopoietic stem cell types
Prepare media, reagents, and cell culture materials.
Perform general molecular and cellular biology experiments according to established protocols.
Monitor cell morphology, viability, and culture quality.
Maintain accurate experimental records and documentation.
Follow strict sterile and aseptic working procedures.
Assist with laboratory purchasing, organization, reagent preparation, and routine maintenance.
Developing and optimizing differentiation protocols, cellular assays, and quality control strategies to generate reproducible, scalable, and biologically relevant stem cell-derived models.
Contributing to grant applications, technical reports, manuscripts, presentations, SOP development, and scientific communications.
Mentoring research associates, trainees, and junior scientists while fostering a collaborative and innovative laboratory environment.
May supervisor junior level research staff
Assisting with laboratory management, including implementation of new technologies, oversight of laboratory resources, and ensuring compliance with biosafety and quality standards.
Remaining current with advances in stem cell biology, developmental biology, and organoid technologies, and implement emerging methodologies.
Qualifications
Ph.D. in Biological Science or related field
Three years experience.
Preferred Skills
Must possess basic Microsoft Office skills.
Demonstrated expertise in mammalian cell culture, aseptic technique, and advanced molecular and cellular biology methodologies.
Demonstrated experience with human iPSC reprogramming, culture, characterization, genome editing, and directed differentiation.
Experience designing, executing, troubleshooting, and optimizing complex scientific experiments independently.
Strong organizational and project management skills with the ability to lead multiple projects simultaneously.
Excellent written and verbal communication skills, including preparation of manuscripts, technical reports, and scientific presentations.
Experience mentoring junior scientists or research staff.
Experience with molecular and cellular biology techniques such as qPCR, flow cytometry, RNA analysis, plasmid construction.
Strong organizational, communication, and problem-solving skills.
Ability to work independently while contributing effectively within a collaborative research environment.
Strong scientific publication record appropriate to career stage.
Experience with handling mice.
About Mount Sinai Hospital
Mount Sinai Hospital is a hospital network based in New York City. It was founded in 1852 and is one of the oldest and largest teaching hospitals in the United States. The hospital has been ranked among the top hospitals in the country by U.S. News & World Report and is known for its excellence in patient care, research, and education. Mount Sinai Hospital is affiliated with the Icahn School of Medicine at Mount Sinai and has a staff of over 7,000 physicians, nurses, and other healthcare professionals.